5/5/2025
Last update
5/5/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.7
USERS' SCORE
Good
Based on 1 Review
8.5
Top Medical Research Studies
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
Most Useful Reviews
9
No post-surgery nausea
1 people found this helpful
Taste good and doesn't upset my post-VSG tummy! I've been taking two a day for a week post-surgery, and I haven’t experienced nausea, vomiting, or stomach pain. These were recommended by my dietitian at USC Keck in Los Angeles instead of bariatric chewable vitamins.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.7
- All Researches
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
7
Ferric carboxymaltose reduces nausea
This randomized controlled trial explored how low-dose ferric carboxymaltose (FCM) affects hemoglobin levels and nausea in postpartum East Asian women. Participants received either an intravenous FCM infusion or oral iron for four weeks.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
No post-surgery nausea
1 people found this helpful
Taste good and doesn't upset my post-VSG tummy! I've been taking two a day for a week post-surgery, and I haven’t experienced nausea, vomiting, or stomach pain. These were recommended by my dietitian at USC Keck in Los Angeles instead of bariatric chewable vitamins.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Foessleitner P, Rager L, Mikula F, Hager M, Granser S, et al. The Role of hCG and Histamine in Emesis Gravidarum and Use of a Chewing Gum Containing Vitamin C as a Treatment Option: A Double-Blinded, Randomized, Controlled Trial. J Clin Med. 2024;13. 10.3390/jcm13175099
- Koch KL, Parkman HP, Yates KP, Van Natta ML, Grover M, et al. Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity. Dig Dis Sci. 2024;69:2904. 10.1007/s10620-024-08520-8
- Jarosz AC, Noori D, Zeitoun T, Garcia-Bailo B, El-Sohemy A. Variation in the vitamin D receptor gene, plasma 25-hydroxyvitamin D, and risk of premenstrual symptoms. Genes Nutr. 2021;16:15. 10.1186/s12263-021-00696-2
- Srivastav A, Kshirsagar S, Adhav T, Ganu G, Shah A. Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy. Cureus. 2024;16:e57108. 10.7759/cureus.57108
- Schulte J, Peterson K, Thomsen T, Lentz S, Hall M, et al. Daily versus three times weekly dosing for treatment of iron deficiency nonanemia in NCAA Division 1 female athletes. PM R. 2024;16:316. 10.1002/pmrj.13172
- Nagao T, Takahashi K, Takahashi S, Yokomizo R, Samura O, et al. Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial. PLoS One. 2025;20:e0319795. 10.1371/journal.pone.0319795
- Wada-Hiraike O, Maruyama A, Mitobe Y, Iriyama T, Mori-Uchino M, et al. A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH. Adv Ther. 2025. 10.1007/s12325-025-03123-9
