Now Foods D-Mannose Powder

We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.

While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.

Infection-free living

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53 people found this helpful

An AMAZING product! I endured chronic bladder infections for almost five years, trying numerous antibiotics and alternative treatments. Then, someone recommended D-Mannose, and I thought "why not?" I bought it, and within hours, my symptoms vanished. I'm now free from infections, antibiotics, and yeast infection. D-Mannose is fantastic; I wish I'd known about it five years ago.

We explored a new targeted agent designed to treat atherosclerosis by focusing on macrophage-mannose receptors. This study tested the effectiveness and safety of a specially formulated nanoagent in a mouse model of atherosclerosis.

The agent showed a notable reduction in inflammation within the arterial plaques while being well-tolerated in terms of toxicity. We found it had good imaging capabilities, allowing for better visualization of macrophages linked to atherosclerosis.

Overall, this promising approach may improve both the diagnosis and treatment of cardiovascular diseases linked to atherosclerosis.

Chronic cystitis beaten

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15 people found this helpful

D-Mannose has been life-changing for me! This simple saccharide binds E. coli in the bladder, preventing outbreaks of cystitis. I take three capsules at the first signs of an attack, stopping the bacterial growth effectively. After ceasing hormonal pills—previously taken for over a year—I was relieved not to face another bout of cystitis after three months. My experience has positively transformed my life, and I hope my review encourages others to try it!

Diabetes details

Prevents UTIs effectively

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5 people found this helpful

Excellent help for UTI, I discovered D-Mannose by chance - a true answer to my prayers. As a diabetic, I used to struggle with urinary tract infections when my diabetes was poorly controlled. I developed a resistance to antibiotics, which was quite frightening. UTIs are painful! I never go without Now Food's D-Mannose powder. I generally take a maintenance dose of 1/2 to 1 teaspoon daily, but since my diabetes has improved, I often manage a week without any. I’ve become attuned to the early symptoms and promptly take a teaspoon or two at the first signs, effectively addressing the issue before it escalates. I highly recommend D-Mannose, as Now Foods offers the best price.

Lung Cancer details

1 people found this helpful

My husband uses D-Mannose every day as part of his regimen following his bladder cancer treatment and neobladder surgery. Since he began taking it, he has experienced no further urinary tract infections.

Abscess details

Eliminated sensitivity

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I bought this product based on a recommendation and it has been excellent. I had been suffering for the past six months with a blister and inflammation that antibiotics did not alleviate. This product was the only thing that helped and removed my sensitivity. I noticed a decrease in my discomfort during pregnancy as well.

Bone Pain details

D-mannose may mitigate IVDD symptoms

Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, et al. D-mannose alleviates intervertebral disc degeneration through glutamine metabolism. Mil Med Res. 2024;11:28. doi:10.1186/s40779-024-00529-4

We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.

Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.

Miracle solution

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22 people found this helpful

Years of torment resolved with Mannosa! After suffering chronic cystitis for six years, the condition became unbearable with frequent infections and severe bone pain. Traditional treatments seemed futile, but after using Mannosa, my symptoms dwindled significantly within months. I took a small dosage before bed, and if I felt discomfort, a quick drink of Mannosa alleviated it immediately. Now I rarely use it, opting for prevention when needed, and I highly recommend it for anyone who shares this affliction.

High Cholesterol details

1 people found this helpful

Thank you very much for this product! I used to suffer from postcoital cystitis and frequently relied on antibiotics. Now, thanks to D-Mannose, I've completely forgotten what cystitis feels like! I highly recommend it!

Kidney Infection details

11 people found this helpful

I recommend this to anyone who suffers from chronic cystitis or knows the insidious nature of it! I was frustrated with the endless antibiotics that worked for no more than a month. Initially, I ordered it in pill form, but the powder is more cost-effective. I take it continuously for half a day daily, and for 1.5 months, I have been cystitis-free. During acute episodes, I increased the dose and drank plenty of water. Additionally, I have chronic pyelonephritis, with sand and stones in my kidneys. Today, to my amazement, the ultrasound showed my kidneys are clear, without signs of sand or pyelonephritis. I am extremely grateful for this product and recommend taking it with cranberries.

Menopause details

SCIENTIFIC SCORE

Moderately Effective

Based on 3 Researches

D-mannose aids menopausal UTI management

Mainini G, Passaro M, Schiattarella A, Franciscis P, Donna MCD, et al. Prevention and treatment of cystitis during menopause: efficacy of a nutraceutical containing D-mannose, inulin, cranberry, bearberry, and . Prz Menopauzalny. 2020;19:130. doi:10.5114/pm.2020.99567

We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.

At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.

Preventative measure

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Cleared up a stubborn UTI in a couple of days. I will take it regularly as a preventative since hitting menopause, as I have been getting UTIs - something I had never experienced before in my life!

Candidiasis details

57 people found this helpful

Thanks to the creator, this is a miracle powder! I have suffered from chronic cystitis for three years, constantly having acute flare-ups treated with antibiotics, which ultimately harmed my microflora and led to constant thrush. After trying D-mannose, I felt immediate relief after the first dose. I took two capsules in the morning and evening. During my first course, while I had a cold, my symptoms persisted but eventually subsided after additional treatment. Now, cystitis is hardly an issue; I only take mannose after intimate activities. I've ordered more for future needs. Those with similar issues should try this instead of relying on antibiotics!

Cold Sores details

2 people found this helpful

Massive results! I cannot believe how effective this powder is! Since I've been taking it for about a month, primarily around the time of intercourse, I haven’t had any urinary tract issues. It comes as a white powder with little taste. The dosage is one teaspoon, and it dissolves well in cold water. I read many reviews before trying it, but my fertility consultant mentioned its benefits.

Food Poisoning details

19 people found this helpful

It works! Buy D-mannose and give it a try! If you suffer from cystitis repeatedly and antibiotics do not help, and E. coli continuously resides in your urine, then try D-mannose. I only take one teaspoon a day, sometimes less, and nothing bothers me. It's a shame that in Russia we are overloaded with antibiotics.

SCIENTIFIC SCORE

Moderately Effective

Based on 5 Researches

d-mannose may alleviate psoriasis

Jiang Q, Wei B, You M, Zhou X. d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice. Int Immunopharmacol. 2023;118:110087. doi:10.1016/j.intimp.2023.110087

We explored whether d-mannose can help alleviate psoriasis, an autoimmune condition that causes significant discomfort. Our study demonstrated that both oral and topical applications of d-mannose were effective in reducing psoriasis symptoms in mice.

We discovered that it works by lowering levels of a protein called HIF-1α and the chemokine CCL20 in skin cells. This inhibition interrupts the harmful cycle between keratinocytes and Th17 immune cells. Overall, this suggests d-mannose could be a helpful treatment option for managing psoriasis.

Cystitis relief

Most Useful Review

57 people found this helpful

Thanks to the creator, for this is a MIRACLE powder. I've suffered with chronic cystitis for 3 years, experiencing monthly flare-ups. I relied on antibiotics like ciprofloxacin, which destroyed my microflora and led to constant thrush. Desperate for relief, I stumbled upon D-mannose. I ordered a small jar and felt relief after my first dose. I took two capsules morning and evening, and importantly, now, I only need D-mannose after intercourse. My symptoms have lessened significantly, and I no longer suffer from cystitis. I have since ordered larger jars as backups. Why isn’t this product prescribed in Russia? I wish everyone good health!

Sleep Apnea details

This is great! It is pharmaceutical-grade quality and very clean. It definitely benefits me; my frequent urination stops when taken every night before sleep.

Urinary Tract Infection details

SCIENTIFIC SCORE

Questionable

Based on 17 Researches

D-Mannose shows effective UTI treatment

Salvatore S, Ruffolo AF, Stabile G, Casiraghi A, Zito G, et al. A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections. Eur Urol Focus. 2023;9:654. doi:10.1016/j.euf.2022.12.013

We evaluated a D-mannose-based dietary supplement, the DAPAD complex, to see if it could effectively treat uncomplicated E. coli urinary tract infections (UTIs).

Conducted as a randomized, double-blind trial in India, our study involved 70 nonmenopausal women.

The results were promising: at day six, the DAPAD group showed much higher clinical resolution (34.3% vs. 0%) and effective bacteriological resolution (85.7% vs. 14.3%).

By day 35, symptoms were completely resolved for all in the DAPAD group, while the placebo group still had patients with moderate or severe symptoms.

Potent product

Most Useful Review

9 people found this helpful

I purchased this product for some friends who had urinary tract infections, and they thanked me for it. It worked for each of them, even in cases where antibiotics failed, indicating its potency. It effectively cleans the urinary tract and I highly recommend it.