Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.1
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Lozenge
Amount Per Serving
%DV
Vitamin B-12 (as Methylcobalamin)
1 mg (1,000 mcg)
41,667%
Top Medical Research Studies
9
We conducted a study to investigate the effects of mecobalamin, a form of vitamin B12, on carpal tunnel syndrome (CTS) in stroke patients. Our research involved a group of 135 stroke patients, with 67 receiving 1,500 micrograms of mecobalamin daily for two years, while the other 68 patients did not receive any treatment.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Read More
8
Methylcobalamin shows promise for carpal tunnel
We explored the potential benefits of vitamin B12, specifically methylcobalamin, in treating carpal tunnel syndrome. This vitamin is essential for maintaining the nervous system and has shown promise in easing symptoms associated with peripheral nerve disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Read More
9
We explored the clinical effects of a treatment approach involving vitamin B12 for patients with carpal tunnel syndrome. Our study included a total of 60 patients divided into two groups: one receiving needle Dao treatment and the other treated with a combination of a brace and vitamin B12, among other medications.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
Read More
Most Useful Reviews
9
No more numbness
10 people found this helpful
No more finger numbness! I was diagnosed with Carpal Tunnel Syndrome and began searching for solutions, which led me to this supplement. After about a week of taking it, I noticed the numbness in my fingertips diminishing, and a month later, it has completely disappeared. It’s worth noting that the Carpal Tunnel Syndrome was relatively mild.
Read More
9
Quick improvement
1 people found this helpful
Following a mild case of Carpal Tunnel Syndrome, I was prescribed B12 at the hospital. When the numbness recurred, life with a child prevented me from visiting the hospital, so I tried this supplement instead. To my surprise, my condition improved quite rapidly! The candy tastes like acerola and is easy to incorporate into my daily routine. I will definitely purchase it again.
Read More
6
Slightly improved
8 people found this helpful
It’s quite delicious and shows promising results. The taste is reminiscent of berries. I take about four 1000mg tablets daily. While they don’t dissolve easily under the tongue, I lightly chew them for better absorption. I noticed some improvement in the numbness in my hands due to Carpal Tunnel Syndrome.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.1
- All Researches
9
We explored the clinical effects of a treatment approach involving vitamin B12 for patients with carpal tunnel syndrome. Our study included a total of 60 patients divided into two groups: one receiving needle Dao treatment and the other treated with a combination of a brace and vitamin B12, among other medications.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
Read More
9
We explored the effects of a combination treatment involving uridine monophosphate, folic acid, and vitamin B12 on patients suffering from carpal tunnel syndrome, the most prevalent form of peripheral entrapment neuropathy. In our open-label study, 48 patients were given a daily capsule containing these three components over a two-month period.
By using the Pain DETECT questionnaire, we aimed to assess any improvements in pain levels and related symptoms. The results were encouraging, with overall pain scores dropping significantly—from an average of 17.3 to 10.3. Notably, many participants were able to either stop or reduce their use of analgesics and anti-inflammatory medications during the study.
Despite the positive findings, it's essential to highlight that the benefits observed were attributed to the combination of substances and not solely to vitamin B12. Therefore, to better understand the role of each component, particularly vitamin B12, further well-structured and larger randomized controlled trials are needed.
By using the Pain DETECT questionnaire, we aimed to assess any improvements in pain levels and related symptoms. The results were encouraging, with overall pain scores dropping significantly—from an average of 17.3 to 10.3. Notably, many participants were able to either stop or reduce their use of analgesics and anti-inflammatory medications during the study.
Despite the positive findings, it's essential to highlight that the benefits observed were attributed to the combination of substances and not solely to vitamin B12. Therefore, to better understand the role of each component, particularly vitamin B12, further well-structured and larger randomized controlled trials are needed.
Read More
9
We conducted a study to investigate the effects of mecobalamin, a form of vitamin B12, on carpal tunnel syndrome (CTS) in stroke patients. Our research involved a group of 135 stroke patients, with 67 receiving 1,500 micrograms of mecobalamin daily for two years, while the other 68 patients did not receive any treatment.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Read More
8
Methylcobalamin shows promise for carpal tunnel
We explored the potential benefits of vitamin B12, specifically methylcobalamin, in treating carpal tunnel syndrome. This vitamin is essential for maintaining the nervous system and has shown promise in easing symptoms associated with peripheral nerve disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Read More
7
Vitamin B12 benefits unclear in CTS
We aimed to understand how vitamin B12 affects carpal tunnel syndrome (CTS) treatment. While vitamin B12 was included as part of a broader conservative treatment strategy, the specifics of its isolated effectiveness remain unclear.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
No more numbness
10 people found this helpful
No more finger numbness! I was diagnosed with Carpal Tunnel Syndrome and began searching for solutions, which led me to this supplement. After about a week of taking it, I noticed the numbness in my fingertips diminishing, and a month later, it has completely disappeared. It’s worth noting that the Carpal Tunnel Syndrome was relatively mild.
Read More
9
Quick improvement
1 people found this helpful
Following a mild case of Carpal Tunnel Syndrome, I was prescribed B12 at the hospital. When the numbness recurred, life with a child prevented me from visiting the hospital, so I tried this supplement instead. To my surprise, my condition improved quite rapidly! The candy tastes like acerola and is easy to incorporate into my daily routine. I will definitely purchase it again.
Read More
6
Slightly improved
8 people found this helpful
It’s quite delicious and shows promising results. The taste is reminiscent of berries. I take about four 1000mg tablets daily. While they don’t dissolve easily under the tongue, I lightly chew them for better absorption. I noticed some improvement in the numbness in my hands due to Carpal Tunnel Syndrome.
Read More
7.5
Very effective
1 people found this helpful
missusb really helps with my severe Carpal Tunnel Syndrome.
Read More
Frequently Asked Questions
9
No more numbness
10 people found this helpful
No more finger numbness! I was diagnosed with Carpal Tunnel Syndrome and began searching for solutions, which led me to this supplement. After about a week of taking it, I noticed the numbness in my fingertips diminishing, and a month later, it has completely disappeared. It’s worth noting that the Carpal Tunnel Syndrome was relatively mild.
9
Quick improvement
1 people found this helpful
Following a mild case of Carpal Tunnel Syndrome, I was prescribed B12 at the hospital. When the numbness recurred, life with a child prevented me from visiting the hospital, so I tried this supplement instead. To my surprise, my condition improved quite rapidly! The candy tastes like acerola and is easy to incorporate into my daily routine. I will definitely purchase it again.
6
Slightly improved
8 people found this helpful
It’s quite delicious and shows promising results. The taste is reminiscent of berries. I take about four 1000mg tablets daily. While they don’t dissolve easily under the tongue, I lightly chew them for better absorption. I noticed some improvement in the numbness in my hands due to Carpal Tunnel Syndrome.
7.5
Very effective
1 people found this helpful
missusb really helps with my severe Carpal Tunnel Syndrome.
7
Vitamin B12 benefits unclear in CTS
We aimed to understand how vitamin B12 affects carpal tunnel syndrome (CTS) treatment. While vitamin B12 was included as part of a broader conservative treatment strategy, the specifics of its isolated effectiveness remain unclear.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
9
We explored the clinical effects of a treatment approach involving vitamin B12 for patients with carpal tunnel syndrome. Our study included a total of 60 patients divided into two groups: one receiving needle Dao treatment and the other treated with a combination of a brace and vitamin B12, among other medications.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
8
Methylcobalamin shows promise for carpal tunnel
We explored the potential benefits of vitamin B12, specifically methylcobalamin, in treating carpal tunnel syndrome. This vitamin is essential for maintaining the nervous system and has shown promise in easing symptoms associated with peripheral nerve disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
4
We explored the effectiveness of different treatments for carpal tunnel syndrome, focusing specifically on vitamin B12's role. In our study, we looked at 61 patients with a total of 99 affected hands and compared five treatment approaches. These included the use of vitamins B6 and B12, steroid injections, hand splints, and combinations of these methods.
After assessing each patient with electrodiagnostic studies before treatment and again after one and two months, we found that treatments involving hand splinting, local steroid injections, and combination therapies delivered better results when it came to sensory nerve conduction studies. Notably, vitamin B12 used alone did not show substantial benefits. In fact, the combined treatments that included steroid injections appeared to work faster and more effectively for relieving symptoms.
Overall, our findings suggest that relying solely on vitamin B12 for carpal tunnel syndrome is not sufficient. Instead, a combination approach, particularly involving steroid injections and splinting, seems to be a more effective conservative treatment option for this condition.
After assessing each patient with electrodiagnostic studies before treatment and again after one and two months, we found that treatments involving hand splinting, local steroid injections, and combination therapies delivered better results when it came to sensory nerve conduction studies. Notably, vitamin B12 used alone did not show substantial benefits. In fact, the combined treatments that included steroid injections appeared to work faster and more effectively for relieving symptoms.
Overall, our findings suggest that relying solely on vitamin B12 for carpal tunnel syndrome is not sufficient. Instead, a combination approach, particularly involving steroid injections and splinting, seems to be a more effective conservative treatment option for this condition.
9
We explored the effects of a combination treatment involving uridine monophosphate, folic acid, and vitamin B12 on patients suffering from carpal tunnel syndrome, the most prevalent form of peripheral entrapment neuropathy. In our open-label study, 48 patients were given a daily capsule containing these three components over a two-month period.
By using the Pain DETECT questionnaire, we aimed to assess any improvements in pain levels and related symptoms. The results were encouraging, with overall pain scores dropping significantly—from an average of 17.3 to 10.3. Notably, many participants were able to either stop or reduce their use of analgesics and anti-inflammatory medications during the study.
Despite the positive findings, it's essential to highlight that the benefits observed were attributed to the combination of substances and not solely to vitamin B12. Therefore, to better understand the role of each component, particularly vitamin B12, further well-structured and larger randomized controlled trials are needed.
By using the Pain DETECT questionnaire, we aimed to assess any improvements in pain levels and related symptoms. The results were encouraging, with overall pain scores dropping significantly—from an average of 17.3 to 10.3. Notably, many participants were able to either stop or reduce their use of analgesics and anti-inflammatory medications during the study.
Despite the positive findings, it's essential to highlight that the benefits observed were attributed to the combination of substances and not solely to vitamin B12. Therefore, to better understand the role of each component, particularly vitamin B12, further well-structured and larger randomized controlled trials are needed.
References
- Kokubo R, Kim K. [Carpal Tunnel Syndrome:Diagnosis and Treatment]. No Shinkei Geka. 2021;49:1306. doi:10.11477/mf.1436204516
- Zhang KY, Yang Y, Xu SW, Shou Y, Jiang HR, et al. [A case-control study on the treatment of carpal tunnel syndrome with needle Dao]. Zhongguo Gu Shang. 2018;31:497. doi:10.3969/j.issn.1003-0034.2018.06.002
- Negrão L, Nunes P. Uridine monophosphate, folic acid and vitamin B12 in patients with symptomatic peripheral entrapment neuropathies. Pain Manag. 2016;6:25. doi:10.2217/pmt.15.60
- Tanaka H. [Old or new medicine? Vitamin B12 and peripheral nerve neuropathy]. Brain Nerve. 2013;65:1077.
- Zhang CY, Wang YX. [Observation on therapeutic effects of acupuncture combined with TDP irradiation and chinese herbal steaming and washing therapy for treatment of carpal tunnel syndrome in early stage]. Zhongguo Zhen Jiu. 2009;29:708.
- Di Geronimo G, Caccese AF, Caruso L, Soldati A, Passaretti U. Treatment of carpal tunnel syndrome with alpha-lipoic acid. Eur Rev Med Pharmacol Sci. 2009;13:133.
- Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K. Amelioration by mecobalamin of subclinical carpal tunnel syndrome involving unaffected limbs in stroke patients. J Neurol Sci. 2005;231:13.
- Wu SF, Chan RC, Hsu TC. [Electrodiagnostic evaluation of conservative treatment in carpal tunnel syndrome]. Zhonghua Yi Xue Za Zhi (Taipei). 1991;48:125.
