5/28/2025
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 41 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1,111%
Rose Hips Powder (Rosa canina) (Fruit)
25 mg
†
Citrus Bioflavonoid Complex
25 mg
†
Top Medical Research Studies
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More
Most Useful Reviews
9
Immunity booster
14 people found this helpful
In the season of colds, I buy these for the entire family. Taking one capsule each morning works wonders! We haven't fallen ill for three years following this routine. I highly recommend it – this will be an invaluable aid for your whole family!
Read More
9
Instant relief
9 people found this helpful
If you want to boost your immunity and forget what a cold feels like, these pills are a great choice. With a high concentration of Vitamin C, they work quickly. I noticed no hint of sickness by the next day. Highly recommended for the whole family!
Read More
9
Early cold remedy
4 people found this helpful
A blow for the common cold. I constantly order vitamin C in case of a cold. At the first sign, I take 3-5 tablets at once. It helps a lot! I appreciate the price and dosage, and I prefer this trusted brand.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Read More
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Read More
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
Read More
User Reviews
USERS' SCORE
Good
Based on 41 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Immunity booster
14 people found this helpful
In the season of colds, I buy these for the entire family. Taking one capsule each morning works wonders! We haven't fallen ill for three years following this routine. I highly recommend it – this will be an invaluable aid for your whole family!
Read More
9
Instant relief
9 people found this helpful
If you want to boost your immunity and forget what a cold feels like, these pills are a great choice. With a high concentration of Vitamin C, they work quickly. I noticed no hint of sickness by the next day. Highly recommended for the whole family!
Read More
9
Early cold remedy
4 people found this helpful
A blow for the common cold. I constantly order vitamin C in case of a cold. At the first sign, I take 3-5 tablets at once. It helps a lot! I appreciate the price and dosage, and I prefer this trusted brand.
Read More
9
Quick recovery from colds
2 people found this helpful
The vitamins are working! I’ve been taking them for the first time. As soon as cold symptoms appear, I take 1 tablet three times, and by the next day, I’m feeling great.
Read More
9
Cold-free child
2 people found this helpful
Relevant, especially today! I will be ordering again. We take vitamin C every day; colds have bypassed us. My child was at school without needing a sick note. The long usage allows breaks, which is convenient. The period of use is fine, and they function normally. Plus, it's an excellent antioxidant! Good vitamins, self-tested!
Read More
Frequently Asked Questions
8
We conducted a clinical pilot study to evaluate the effects of a combination treatment of lignin—a substance derived from pine cones—mixed with vitamin C on cold sores caused by the herpes simplex virus type 1 (HSV-1). Our study included 48 healthy participants, ranging from 4 to 61 years old, who had active lesions of HSV-1.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
Participants received a daily dose of the lignin-ascorbic acid treatment for one month. Notably, those who began the treatment within the first 48 hours after the onset of symptoms did not develop typical cold sore lesions. For others who started later, we observed a shorter duration of cold sores and less severe symptoms compared to their previous outbreaks.
Many participants reported a reduction in both the severity and frequency of their cold sore episodes during treatment. Although the results suggest some benefits of this combination treatment, it’s important to note that vitamin C was part of the blend, making it challenging to evaluate its individual effect on cold sores directly.
Thus, while the combination of lignin and vitamin C appears promising for preventing and treating HSV-1 infection, further studies isolating vitamin C's effects would be helpful to understand its specific role in managing cold sores.
9
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
8
We evaluated the effectiveness of a water-soluble complex combining bioflavonoids and ascorbic acid, which is commonly known as vitamin C, for treating cold sores caused by recurrent herpes labialis. The study involved 50 episodes of cold sores, with patients receiving different dosages of the vitamin C and bioflavonoid combination, while others were given a lactose placebo.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
The regimen was followed for three days after participants felt the initial symptoms. We noted that the combination appeared to reduce the formation of blisters and helped maintain the integrity of the vesicular membrane. The best results came when treatment started during the early warning signs of an outbreak, leading to symptom relief in an average of about 4.2 days with the lower dosage.
Importantly, throughout the study, no adverse reactions were reported by participants. Although the combination product shows promise, it was difficult to isolate the specific impact of vitamin C alone due to its synergy with bioflavonoids.
References
- Lopez BS, Yamamoto M, Utsumi K, Aratsu C, Sakagami H. A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus. In Vivo. 2009;23:1011.
- Hovi T, Hirvimies A, Stenvik M, Vuola E, Pippuri R. Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution. Antiviral Res. 1995;27:263.
- Terezhalmy GT, Bottomley WK, Pelleu GB. The use of water-soluble bioflavonoid-ascorbic acid complex in the treatment of recurrent herpes labialis. Oral Surg Oral Med Oral Pathol. 1978;45:56.
