Vitamin C aids foot ulcer healingVitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
We looked into how well ascorbic acid, or vitamin C, helps heal chronic foot ulcers. In a carefully designed trial, we compared the effects of vitamin C against a placebo on sixteen participants.
Over 8 weeks, those who received vitamin C showed significant healing improvements, with a median healing rate of 100%, compared to a negative healing rate in the placebo group.
Everyone in the vitamin C group avoided amputation, while almost half from the control group did not heal at all. This affordable and accessible treatment could greatly benefit those suffering from chronic foot ulcers.
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Ascorbic acid inhibits ulcer formationProtective effects of a culture supernatant of Lactobacillus acidophilus and antioxidants on ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug.
We examined the effects of ascorbic acid on ileal ulcer formation in rats treated with a specific anti-inflammatory drug.
In our study, while some antioxidants didn’t reduce ulcer formation, ascorbic acid stood out as the most effective at inhibiting ulcers and decreasing harmful substances in the ileal mucosa.
We also noted that ascorbic acid helped maintain healthier gut bacteria levels. This suggests that ascorbic acid can be a helpful ally against ulcers by combatting oxidative stress and supporting gut health.
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Ascorbic acid improves ulcer healing[Scurvy presenting with low-extremity necrotic and purpuric ulcers: Two cases].
We examined the effects of ascorbic acid on two elderly patients suffering from severe ulcers on their lower limbs, attributed to scurvy—a condition caused by a lack of vitamin C. Both individuals showed undetectable vitamin C levels, and after receiving vitamin C supplementation, we noted a significant improvement in the ulcers.
This experience underscores the need to consider scurvy as a possible diagnosis in similar ulcer cases, especially for those with dietary deficiencies. Identifying this condition early can lead to better health outcomes for affected patients.
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Prickly pear juice shows potentialChemical characterization and biological effects of Sicilian Opuntia ficus indica (L.) mill. Fruit juice: antioxidant and antiulcerogenic activity.
We examined the juice from Sicilian prickly pear fruits to see how ascorbic acid and other components affect ulcers. The study involved testing the juice's ability to prevent ulcer formation caused by ethanol in rats.
We discovered that the juice increased mucus production and restored the normal structure of the stomach lining, suggesting it may offer protective benefits. Additionally, its antioxidant properties were highlighted, which could further contribute to overall health. However, our findings don't provide substantial evidence that ascorbic acid alone is a direct cure for ulcers.
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Vitamin C aids gastric ulcer healingConcomitant Effects of Metformin and Vitamin C on Indomethacin-Induced Gastric Ulcer in Rats: Biochemical and Histopathological Approach.
We conducted a thorough investigation into the protective effects of Vitamin C on gastric ulcers, especially in combination with metformin. Our study involved thirty rats divided into different groups to observe the ulcer-inducing effects of indomethacin and the potential healing properties of various treatments.
The findings were promising: both Vitamin C and metformin demonstrated significant improvements in gastric mucosal injury, helping to alleviate the damage caused by indomethacin. We noted that the combination of Vitamin C with metformin enhanced the effectiveness of antioxidant enzymes in the stomach, such as catalase and GPx, indicating a synergistic effect.
While Vitamin C showed positive results, it's important to recognize that these effects were observed in combination with metformin, making it difficult to isolate its specific benefits. Overall, our research suggests that the combination therapy could be a beneficial option for treating gastric ulcers linked to NSAID usage.
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