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SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
USERS' SCORE
Good
Based on 8 Reviews
8
Supplement Facts
Serving Size: 1/4 Level Teaspoon (1.1 g)
Amount Per Serving
%DV
Vitamin C (Ascorbic Acid)
1.1 g (1,100 mg)
1222%
Top Medical Research Studies
8
Vitamin C reduces gastric ulcers
Vitamin C modulates adrenaline-augmented gastric injury via cardiac troponin/creatine kinase pathway in Wistar rats.
Study demonstrates certain benefits
We observed the potential benefits of vitamin C in managing gastric ulcers under conditions of myocardial injury, which was induced using adrenaline in our study. Thirty Wistar rats were carefully divided into five groups, ensuring a control group for comparison.
The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.
Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.
Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
Read More
8
Vitamin C aids gastric ulcer healing
Concomitant Effects of Metformin and Vitamin C on Indomethacin-Induced Gastric Ulcer in Rats: Biochemical and Histopathological Approach.
Combination effects limit isolation
We conducted a thorough investigation into the protective effects of Vitamin C on gastric ulcers, especially in combination with metformin. Our study involved thirty rats divided into different groups to observe the ulcer-inducing effects of indomethacin and the potential healing properties of various treatments.
The findings were promising: both Vitamin C and metformin demonstrated significant improvements in gastric mucosal injury, helping to alleviate the damage caused by indomethacin. We noted that the combination of Vitamin C with metformin enhanced the effectiveness of antioxidant enzymes in the stomach, such as catalase and GPx, indicating a synergistic effect.
While Vitamin C showed positive results, it's important to recognize that these effects were observed in combination with metformin, making it difficult to isolate its specific benefits. Overall, our research suggests that the combination therapy could be a beneficial option for treating gastric ulcers linked to NSAID usage.
The findings were promising: both Vitamin C and metformin demonstrated significant improvements in gastric mucosal injury, helping to alleviate the damage caused by indomethacin. We noted that the combination of Vitamin C with metformin enhanced the effectiveness of antioxidant enzymes in the stomach, such as catalase and GPx, indicating a synergistic effect.
While Vitamin C showed positive results, it's important to recognize that these effects were observed in combination with metformin, making it difficult to isolate its specific benefits. Overall, our research suggests that the combination therapy could be a beneficial option for treating gastric ulcers linked to NSAID usage.
Read More
8
Vitamin C's potential for ulcer healing
Vitamin C supplementation for diabetes management: A comprehensive narrative review.
Moderate evidence on vitamin C
We critically reviewed the effects of vitamin C supplementation on diabetic ulcers, particularly in patients who might benefit from this therapy. Current evidence suggests that vitamin C could play a role in supporting skin healing, which is vital for those suffering from diabetes-related complications like foot ulcers.
Through various studies, we noted that vitamin C might positively influence the healing process of ulcers. This was especially promising for individuals with diabetic foot ulcers, where effective management is crucial. While the evidence indicates potential benefits, it’s important to state that many of these studies have limitations, and we often see mixed results.
As we move forward, robust research focusing exclusively on vitamin C's effectiveness in treating ulcers is essential. Investigating different dosages and effects in diverse populations can help clarify its role and reliability as a supplementary treatment.
Through various studies, we noted that vitamin C might positively influence the healing process of ulcers. This was especially promising for individuals with diabetic foot ulcers, where effective management is crucial. While the evidence indicates potential benefits, it’s important to state that many of these studies have limitations, and we often see mixed results.
As we move forward, robust research focusing exclusively on vitamin C's effectiveness in treating ulcers is essential. Investigating different dosages and effects in diverse populations can help clarify its role and reliability as a supplementary treatment.
Read More
Most Useful Reviews
7.5
Cost-effective megadoses
This NOW Vitamin C is cost-effective and suitable for megadoses of over 10g daily. I've been doing megadoses for about 10 years, and it's crucial for managing my gastric and duodenal ulcers.
Read More
3.8
Buffered recommended
Caution! It’s sour! I tried different vitamin C brands for my husband. Eventually, I opted for a sour, powdered form which I find convenient. But it caused my stomach ulcer to flare up, so I recommend a buffered form for those with gastrointestinal issues.
Read More
9.5
Suitable for gastritis
Sodium ascorbate is one of the best forms of vitamin C, ideal for those with gastritis and ulcers.
Read More
Most Recommended Products for Ulcer
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
8
Vitamin C aids gastric ulcer healing
Concomitant Effects of Metformin and Vitamin C on Indomethacin-Induced Gastric Ulcer in Rats: Biochemical and Histopathological Approach.
Combination effects limit isolation
We conducted a thorough investigation into the protective effects of Vitamin C on gastric ulcers, especially in combination with metformin. Our study involved thirty rats divided into different groups to observe the ulcer-inducing effects of indomethacin and the potential healing properties of various treatments.
The findings were promising: both Vitamin C and metformin demonstrated significant improvements in gastric mucosal injury, helping to alleviate the damage caused by indomethacin. We noted that the combination of Vitamin C with metformin enhanced the effectiveness of antioxidant enzymes in the stomach, such as catalase and GPx, indicating a synergistic effect.
While Vitamin C showed positive results, it's important to recognize that these effects were observed in combination with metformin, making it difficult to isolate its specific benefits. Overall, our research suggests that the combination therapy could be a beneficial option for treating gastric ulcers linked to NSAID usage.
The findings were promising: both Vitamin C and metformin demonstrated significant improvements in gastric mucosal injury, helping to alleviate the damage caused by indomethacin. We noted that the combination of Vitamin C with metformin enhanced the effectiveness of antioxidant enzymes in the stomach, such as catalase and GPx, indicating a synergistic effect.
While Vitamin C showed positive results, it's important to recognize that these effects were observed in combination with metformin, making it difficult to isolate its specific benefits. Overall, our research suggests that the combination therapy could be a beneficial option for treating gastric ulcers linked to NSAID usage.
Read More
8
Vitamin C reduces gastric ulcers
Vitamin C modulates adrenaline-augmented gastric injury via cardiac troponin/creatine kinase pathway in Wistar rats.
Study demonstrates certain benefits
We observed the potential benefits of vitamin C in managing gastric ulcers under conditions of myocardial injury, which was induced using adrenaline in our study. Thirty Wistar rats were carefully divided into five groups, ensuring a control group for comparison.
The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.
Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.
Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
Read More
8
Vitamin C's potential for ulcer healing
Vitamin C supplementation for diabetes management: A comprehensive narrative review.
Moderate evidence on vitamin C
We critically reviewed the effects of vitamin C supplementation on diabetic ulcers, particularly in patients who might benefit from this therapy. Current evidence suggests that vitamin C could play a role in supporting skin healing, which is vital for those suffering from diabetes-related complications like foot ulcers.
Through various studies, we noted that vitamin C might positively influence the healing process of ulcers. This was especially promising for individuals with diabetic foot ulcers, where effective management is crucial. While the evidence indicates potential benefits, it’s important to state that many of these studies have limitations, and we often see mixed results.
As we move forward, robust research focusing exclusively on vitamin C's effectiveness in treating ulcers is essential. Investigating different dosages and effects in diverse populations can help clarify its role and reliability as a supplementary treatment.
Through various studies, we noted that vitamin C might positively influence the healing process of ulcers. This was especially promising for individuals with diabetic foot ulcers, where effective management is crucial. While the evidence indicates potential benefits, it’s important to state that many of these studies have limitations, and we often see mixed results.
As we move forward, robust research focusing exclusively on vitamin C's effectiveness in treating ulcers is essential. Investigating different dosages and effects in diverse populations can help clarify its role and reliability as a supplementary treatment.
Read More
8
Vitamin C reduces mucosal damage
Effects of Vitamin C on the Oral-Nasal Mucosal Damage Caused by Favipiravir in Old and Young Rats.
Mixed effects on ulcer healing
We investigated the effects of vitamin C on mucosal damage caused by the antiviral drug favipiravir in both young and old rats. The study involved administering favipiravir at two different doses, along with vitamin C, over a period of 14 days. After this treatment, we evaluated the oral and nasal mucosa for any histopathological changes.
Our findings revealed that favipiravir led to significant damage, particularly in older rats, with an increase in severe lesions as the drug dosage increased. We observed marked hyperemia and ulcerative conditions in the mucosa. There was also an increase in specific markers that indicate tissue degeneration. However, when vitamin C was introduced alongside favipiravir, it appeared to reduce these harmful effects.
Interestingly, the protective benefits of vitamin C were more noticeable in younger rats and when given at lower doses. This suggests that vitamin C may play a beneficial role in minimizing ulceration caused by favipiravir, thus providing a potential therapeutic avenue for those experiencing side effects from this medication.
Our findings revealed that favipiravir led to significant damage, particularly in older rats, with an increase in severe lesions as the drug dosage increased. We observed marked hyperemia and ulcerative conditions in the mucosa. There was also an increase in specific markers that indicate tissue degeneration. However, when vitamin C was introduced alongside favipiravir, it appeared to reduce these harmful effects.
Interestingly, the protective benefits of vitamin C were more noticeable in younger rats and when given at lower doses. This suggests that vitamin C may play a beneficial role in minimizing ulceration caused by favipiravir, thus providing a potential therapeutic avenue for those experiencing side effects from this medication.
Read More
7
Vitamin C positively influences gut microbiome
Impact of Vitamins, Antibiotics, Probiotics, and History of COVID-19 on the Gut Microbiome in Ulcerative Colitis Patients: A Cross-Sectional Study.
Study examines multiple influencing factors.
We explored how vitamin C affects the gut microbiome of patients with ulcerative colitis (UC) in a study involving 49 outpatient subjects. The participants were evaluated between June and December 2021, and they were divided into groups based on whether they had contracted COVID-19 in the prior six months. Our primary focus was to assess not just the impact of vitamin C, but also to consider the effects of antibiotics, probiotics, and the history of COVID-19 on their gut health.
Interestingly, we observed that those who used vitamin C supplements had more beneficial elements in their gut microbiome compared to those who did not. The study found a significant difference, indicating that vitamin C users had better microbiome readings, suggesting a positive influence on their gut health. However, while vitamin C presented statistically significant results, we noted that other factors such as antibiotic use also played a crucial role.
Importantly, the use of antibiotics negatively impacted the gut microbiome, which raises questions about the interplay between different treatments. There was also no significant impact found regarding mild COVID-19 on patients’ gut microbiomes, adding another layer to our understanding of these interactions. Ultimately, while vitamin C showed promise, the overall picture suggests that it's part of a broader landscape of factors affecting ulcerative colitis.
Interestingly, we observed that those who used vitamin C supplements had more beneficial elements in their gut microbiome compared to those who did not. The study found a significant difference, indicating that vitamin C users had better microbiome readings, suggesting a positive influence on their gut health. However, while vitamin C presented statistically significant results, we noted that other factors such as antibiotic use also played a crucial role.
Importantly, the use of antibiotics negatively impacted the gut microbiome, which raises questions about the interplay between different treatments. There was also no significant impact found regarding mild COVID-19 on patients’ gut microbiomes, adding another layer to our understanding of these interactions. Ultimately, while vitamin C showed promise, the overall picture suggests that it's part of a broader landscape of factors affecting ulcerative colitis.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8
9.5
Suitable for gastritis
Sodium ascorbate is one of the best forms of vitamin C, ideal for those with gastritis and ulcers.
9.5
Effective for ulcers
This is highly effective for treating dysmenorrhea and oral ulcers. I have used it long-term.
9
Cures oral ulcers
NOW Vitamin C is fantastic! I have used it for a long time; it helps treat oral ulcers, colds, and dysmenorrhea effectively!
8
Emergency aid
An essential product in my home. I use it as an emergency remedy at the onset of respiratory ailments for my family. I also take it with collagen. Those with an ulcer should use it cautiously, preferably after meals.
7.5
Cost-effective megadoses
This NOW Vitamin C is cost-effective and suitable for megadoses of over 10g daily. I've been doing megadoses for about 10 years, and it's crucial for managing my gastric and duodenal ulcers.
