I hate to say it but every time I used this before bed I had terrible nightmares overnight. I even took days off from using it then went back on for a day forgetting not to take it before bed and had nightmares again then too. Normally bad dreams are few and far between for me but they're guaranteed if I have 10-15 drops of this before bed. Also, I'm pretty sure my bottle actively made me sick. If I was dedicated about taking it a few days a row in the morning because I'm trying to boost my immune system, by day 3 or 4 I'd start developing a sore throat. I did my last trial of this recently and ended up home sick for 2 days of work from a sinus infection. I've never had a sinus infection before so whether it's a side effect from the bottle or not, it definitely wasn't boosting my immunities. I dropped it in the trash just this weekend, I'll go back to echinacea tea if I feel the need