Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.2
USERS' SCORE
Good
Based on 8 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 60
Amount Per Serving
%DV
Oregano leaf supercritical CO2 extract
230 mg
†
Carvacrol and Thymol
32 mg
†
Top Medical Research Studies
9
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
Read More
9
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
Read More
9.5
Oregano component improves immune regulation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Read More
Most Useful Reviews
9
Prevents illness
2 people found this helpful
I ordered this antivirus supplement on a specialist's recommendation and have not regretted it. Contact with sick individuals has not led to any symptoms this year, whereas last autumn-winter I was ill three times due to my autoimmune disorder. The quality is excellent, and I feel prepared for the cold and flu season.
Read More
9
Joint pain relief
1 people found this helpful
I found Natural ingredients effective against lamblia during treatment. To consolidate my results, I started taking Oregano Oil, which has been beneficial. My joints no longer ache, and my knees have stopped crunching. I have reordered this product.
Read More
9
No muscle pain
This is my repeat order of Gaia Oil of Oregano, which I use as herbal antibiotics. My doctor prescribed levofloxacin, but it caused muscle pain, so I stopped it. I feel much better with Oil of Oregano and have no muscle pain now.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.2
- All Researches
9.5
Oregano component improves immune regulation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Read More
9
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
Read More
9
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevents illness
2 people found this helpful
I ordered this antivirus supplement on a specialist's recommendation and have not regretted it. Contact with sick individuals has not led to any symptoms this year, whereas last autumn-winter I was ill three times due to my autoimmune disorder. The quality is excellent, and I feel prepared for the cold and flu season.
Read More
9
Joint pain relief
1 people found this helpful
I found Natural ingredients effective against lamblia during treatment. To consolidate my results, I started taking Oregano Oil, which has been beneficial. My joints no longer ache, and my knees have stopped crunching. I have reordered this product.
Read More
9
No muscle pain
This is my repeat order of Gaia Oil of Oregano, which I use as herbal antibiotics. My doctor prescribed levofloxacin, but it caused muscle pain, so I stopped it. I feel much better with Oil of Oregano and have no muscle pain now.
Read More
7.5
Antiparasitic effect
I have ordered this several times! It is a fantastic antiparasitic and antifungal supplement that has worked well for me.
Read More
7.5
Supports immune system
4 people found this helpful
Oil of Oregano. I really like Gaia products. They are of high quality and seem effective. I will continue to order this brand to support my immune system. Using it alongside Olive Leaf Oil has improved my toenail fungus more than anything else. I will reorder if necessary.
Read More
Frequently Asked Questions
9
Infection relief
3 people found this helpful
I ordered these for my husband, who has a keratocystic odontogenic tumour. Despite two courses of antibiotics, his infection persisted until he started taking three tablets a day. After ten days, he noticed a significant improvement, and now, after three weeks, the draining seems to have stopped.
8
Digestive aid
4 people found this helpful
This is my second order. I take two capsules, which really aids my digestion and balances stomach acid due to my autoimmune disorder, SIBO. It's gentle on my stomach, has no taste, and I didn’t get ill this time even though my immune system is weak. Good packaging too.
8
Improves immunity
2 people found this helpful
The quality is effective for enhancing my body's immunity. The natural ingredients have improved my respiratory health and helped alleviate intestinal issues. This supplement is among the best I have used, and I consistently order it due to its unique taste and benefits.
9
Prevents illness
2 people found this helpful
I ordered this antivirus supplement on a specialist's recommendation and have not regretted it. Contact with sick individuals has not led to any symptoms this year, whereas last autumn-winter I was ill three times due to my autoimmune disorder. The quality is excellent, and I feel prepared for the cold and flu season.
9
Joint pain relief
1 people found this helpful
I found Natural ingredients effective against lamblia during treatment. To consolidate my results, I started taking Oregano Oil, which has been beneficial. My joints no longer ache, and my knees have stopped crunching. I have reordered this product.
7.5
Supports immune system
4 people found this helpful
Oil of Oregano. I really like Gaia products. They are of high quality and seem effective. I will continue to order this brand to support my immune system. Using it alongside Olive Leaf Oil has improved my toenail fungus more than anything else. I will reorder if necessary.
9
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
9
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
9.5
Oregano component improves immune regulation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
References
- Vujicic M, Nikolic I, Kontogianni VG, Saksida T, Charisiadis P, et al. Ethyl Acetate Extract of Origanum vulgare L. ssp. hirtum Prevents Streptozotocin-Induced Diabetes in C57BL/6 Mice. J Food Sci. 2016;81:H1846. doi:10.1111/1750-3841.13333
- Vujicic M, Nikolic I, Kontogianni VG, Saksida T, Charisiadis P, et al. Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity. Br J Nutr. 2015;113:770. doi:10.1017/S0007114514004048
- Wieten L, van der Zee R, Spiering R, Wagenaar-Hilbers J, van Kooten P, et al. A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis. Arthritis Rheum. 2010;62:1026. doi:10.1002/art.27344
