Supplement Facts
Serving Size: 3 Capsules
Amount Per Serving
%DV
Total Carbohydrate
1 g
<1%*
Organic Silactive® Milk Thistle (Silybum marianum) seed extract
750 mg
Silymarins 
375 mg

The product is found useful for the following medical conditions

Acne details

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.6
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
9
Amazing acne remedy
Most Useful Review
137 people found this helpful
This stuff is amazing for healing my acne! I've struggled since age 10, and after various treatments, I found that after only one week of taking milk thistle, my acne began to heal significantly. I only take one capsule instead of three, and it has worked wonders, particularly during my PMS.

Bloating details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Bloating relief
Most Useful Review
Excellent! I have tried many brands of milk thistle, but none were effective. Trying this for the first time, I am quite impressed. The heaviness and bloated feeling have vanished, and I feel more energetic. My digestion has improved noticeably.

Constipation details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Effective relief
Most Useful Review
1 people found this helpful
Milk thistle has been my salvation for nearly a decade. It aids me in managing constipation issues due to bile stasis. I particularly prefer this brand, as the capsules are small and easy to swallow. The effect is almost immediate, with no noticeable taste, and I appreciate the dark glass packaging. I take it in the evening, as liver processes predominantly occur at night.

Food Poisoning details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Nausea relief
Most Useful Review
4 people found this helpful
I bought this to replace my usual brand that was out of stock, and I think it might be even better. I tend to feel nauseated when I consume too much “flavourful” food, and milk thistle is the only remedy that improves my condition. I tried the liquid form but find the pills much faster and more effective. I just take one and have a nap, and upon waking, I often feel much better; it usually eliminates my nausea. It’s truly a natural lifesaver for me during those times.

Cardiovascular Disease details

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.4
We examined the effects of Silybum marianum (SM) on heart health through a study on pigs with myocardial infarction. Our findings revealed that administering SM for ten days significantly lowered plasma triglycerides and reduced triglyceride absorption.

Notably, this outcome correlated with reduced cardiac lipotoxicity three weeks after the heart incident and better cardiac structure. Importantly, we observed no adverse effects from SM. Overall, while SM shows promise in improving certain heart conditions, further research could clarify its broader application.
9
Overworked liver relief
Most Useful Review
This is the most effective milk thistle I've tried! I’ve experimented with many brands, but this one is the best for me. My liver is quite overworked, and it helps ease its functions, making me feel much better.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
10
Fatigue alleviated
Most Useful Review
The active ingredient content in milk thistle is high. After taking it, my fatigue disappeared. It's very effective. This is my third purchase for home essentials.

Pelvic Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.4
7.5
Helps relieve pain
Most Useful Review
7 people found this helpful
This product has consistently been beneficial for me. It supports my liver, and as a result of using this product, the pelvic pain diminishes. Additionally, it enhances my vision.

Sleep Apnea details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
Quickly fell asleep
Most Useful Review
After eating, I slept well and fell asleep quickly on the first night. Highly recommended.

Autoimmune Disorder details

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 5 Reviews
8.3
We investigated how silybin, a unique flavonoid found in certain plants, impacts autoimmune disorders, specifically using a model for multiple sclerosis called experimental autoimmune encephalomyelitis (EAE).

In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.

The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.
9
Significant improvement
Most Useful Review
7 people found this helpful
The delivery to the UK via DHL arrived early, which was great. This is the second time I have tried Gaia Herbs Milk Thistle. The first time I used it was due to severe vertigo that left me bed bound for months, prompted by a dream that claimed “it was poison and to get milk thistle”! Gaia Herbs boasted the best reviews concerning liver lab reports, so I decided to try it. After one bottle of 120 capsules, I felt much better, and by the second bottle, I was no longer dizzy. Now, three years later, I ordered more from this company, which was delivered very quickly. Thank you very much.

Blood Clot details

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.3
We aimed to explore how flavonolignans from silybum marianum, specifically silybin, silychristin, and silydianin, affect blood clotting through the COX pathway in platelets. Our methods involved analyzing platelet aggregation and the formation of COX pathway metabolites.

The findings were promising; these compounds showed a reduction in platelet aggregation and COX activity. Silychristin and silybin emerged as the most effective inhibitors, potentially acting as competitive blockers at the active COX site. This suggests that flavonolignans might offer new avenues for antiplatelet and anti-inflammatory therapies.
7.5
Improved liver health
Most Useful Review
11 people found this helpful
The most effective Milk Thistle seed extract I have used. I took it as a liver detox supplement after my blood test showed an elevated fatty liver issue. My doctor advised it wasn't severe enough for a prescription but suggested Milk Thistle instead. I had tried four other cheaper brands, but after deciding to try Gaia Herbs Milk Thistle, I noticed a difference after three months. I have now been taking Milk Thistle extract for over a year.

High Cholesterol details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.3
We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.

Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.

However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
9
Combats bitter taste
Most Useful Review
6 people found this helpful
Prescribed by my dietician, these have genuinely worked for me. I experienced a bitter taste in my mouth for months until I began taking them before meals. The cheaper alternatives weren’t nearly as effective. Once ingested, the effect of Milk Thistle is evident, prompting me to eat immediately. The bitter taste has disappeared, and my husband and son take them as well. They assist in detoxifying the pancreas and liver and are pleasantly sized and easy to swallow, packaged in a glass bottle, avoiding harmful plastic.

Liver Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 38 Reviews
8
We investigated the effects of silymarin on liver and heart health under oxidative stress from paracetamol. In a controlled study with 28 male mice, silymarin showed a strong potential to reduce liver injury markers and improve liver enzyme levels after treatment.

Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.
9
Normal liver tests
Most Useful Review
9 people found this helpful
I have an autoimmune liver disease and I'm so thankful for this product. Every liver test I take is in the normal range. I am not on any other medicine, just this product which I have been taking for the last two years.
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