Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 3 Capsules
Amount Per Serving
%DV
Total Carbohydrate
1 g
<1%*
Organic Silactive® Milk Thistle (Silybum marianum) seed extract
750 mg
Silymarins 
375 mg

Top Medical Research Studies

We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Read More
7
Effectiveness of Silybum marianum on acne
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.

While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
Read More
9
Effective, but limited by other treatments
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.

We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.

However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
Read More

Most Useful Reviews

9
Amazing acne remedy
137 people found this helpful
This stuff is amazing for healing my acne! I've struggled since age 10, and after various treatments, I found that after only one week of taking milk thistle, my acne began to heal significantly. I only take one capsule instead of three, and it has worked wonders, particularly during my PMS.
Read More
9
Clear skin achieved
The cleansing of the liver, the freshness of my face, and the disappearance of acne are exceptional. Before using it, one should read about the product and any possible symptoms.
Read More
7.5
Temporary improvement
This excellent milk thistle improves the condition of my problem skin, particularly with hormonal acne. I take it for 2-3 months, followed by a break. The only downside is that it only works while I'm taking it, and the acne returns afterwards.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
  • All Researches
9
Effective, but limited by other treatments
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.

We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.

However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
Read More
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Read More
7
Effectiveness of Silybum marianum on acne
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.

While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Amazing acne remedy
137 people found this helpful
This stuff is amazing for healing my acne! I've struggled since age 10, and after various treatments, I found that after only one week of taking milk thistle, my acne began to heal significantly. I only take one capsule instead of three, and it has worked wonders, particularly during my PMS.
Read More
9
Clear skin achieved
The cleansing of the liver, the freshness of my face, and the disappearance of acne are exceptional. Before using it, one should read about the product and any possible symptoms.
Read More
7.5
Temporary improvement
This excellent milk thistle improves the condition of my problem skin, particularly with hormonal acne. I take it for 2-3 months, followed by a break. The only downside is that it only works while I'm taking it, and the acne returns afterwards.
Read More

Frequently Asked Questions

7.5
Temporary improvement
This excellent milk thistle improves the condition of my problem skin, particularly with hormonal acne. I take it for 2-3 months, followed by a break. The only downside is that it only works while I'm taking it, and the acne returns afterwards.
9
Clear skin achieved
The cleansing of the liver, the freshness of my face, and the disappearance of acne are exceptional. Before using it, one should read about the product and any possible symptoms.
7
Effectiveness of Silybum marianum on acne
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.

While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
9
Effective, but limited by other treatments
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.

We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.

However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.

References

  1. Bageorgou F, Li L, Beausillon C, Stennevin A, Ortiz-Brugués A, et al. Tolerability and effectiveness of a dermocosmetic product containing Silybum marianum fruit extract in adolescents and young adults with acne-prone skin: An international, phase IV, longitudinal study. J Cosmet Dermatol. 2023;22:2259. doi:10.1111/jocd.15705
  2. Saurat JH, Reygagne P, Josse G, Hamidou Z, Bianovici S, et al. Long-Term Use of Contributes to Homeostasis in Acne-Prone Skin-A 12-Month Follow-Up International "Real Life" Cohort Study. J Pers Med. 2022;13. doi:10.3390/jpm13010096
  3. Fontao F, von Engelbrechten M, Seilaz C, Sorg O, Saurat JH. Microcomedones in non-lesional acne prone skin New orientations on comedogenesis and its prevention. J Eur Acad Dermatol Venereol. 2020;34:357. doi:10.1111/jdv.15926
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