We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
Read More
9
Lactobacillus L-92 shows eczema benefits
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis.
We examined the effects of Lactobacillus rhamnosus HN001 on eczema prevention among children with genetic predispositions. In our double-blind, randomized, placebo-controlled study involving 331 children, we discovered that those with specific high-risk gene variants experienced lower eczema rates when treated with HN001, compared to those receiving a placebo. This suggests Lactobacillus rhamnosus might be particularly beneficial for children at greater genetic risk of eczema and may even influence the severity of eczema and related allergic conditions.
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Most Useful Reviews
10
No more itching
7 people found this helpful
Cured eczema. My 6-year-old was struggling with very itchy eczema spots. A friend suggested this product, and it actually worked! His skin is clear now with no complaints of itchiness. I will certainly be a repeat customer!
Read More
9
Greatly improved condition
1 people found this helpful
This product has greatly improved my daughter’s eczema. I’m not sure how it works, but the results were noticeable within two weeks, and we plan to keep using it for months.
Read More
7.5
Significant improvement
Children enjoy taking them, and their eczema has improved significantly.
We conducted a study to see if giving probiotics to mothers during pregnancy and breastfeeding could help reduce eczema in infants at risk. This double-blind, placebo-controlled trial involved 241 mother-infant pairs, where mothers were given either specific probiotics or a placebo.
Our findings showed that infants whose mothers took Lactobacillus rhamnosus and Bifidobacterium longum had a significantly lower risk of developing eczema in their first two years. This suggests that probiotics can be a safe and effective preventive measure for high-risk infants.
Read More
9
Lactobacillus acidophilus helps eczema
Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model.
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
Read More
9
Lactobacillus L-92 shows eczema benefits
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis.
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
Read More
9
Lactobacillus rhamnosus reduces eczema prevalence
A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years.
We conducted a robust study using a double-blind randomized placebo-controlled trial to explore the impact of Lactobacillus rhamnosus HN001 on eczema in young children.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
Cured eczema. My 6-year-old was struggling with very itchy eczema spots. A friend suggested this product, and it actually worked! His skin is clear now with no complaints of itchiness. I will certainly be a repeat customer!
Read More
9
Greatly improved condition
1 people found this helpful
This product has greatly improved my daughter’s eczema. I’m not sure how it works, but the results were noticeable within two weeks, and we plan to keep using it for months.
Read More
7.5
Significant improvement
Children enjoy taking them, and their eczema has improved significantly.
Read More
7.5
Good quality supplement
Yummy taste. Children like this flavour and chew it like candy. Great quality and easy to store, with no need to refrigerate. My child's eczema improved after taking this supplement. I like this product and will buy it again.
Read More
7.5
Eczema relief seen
I bought a bottle and tried it. After taking it for a few days, my child's breath improved, and it also helped her eczema. Taking advantage of the current discount, I plan to buy again.
Eczema, also known as atopic dermatitis, is a chronic skin condition characterized by inflamed, itchy, and red patches on the skin. It is most commonly seen in children but can occur at any age. The condition can range from mild to severe and often leads to dry, scaly skin that can become cracked or even bleed. Eczema is believed to be related to a combination of genetic predisposition, skin barrier dysfunction, and environmental factors, including allergens, irritants, and stress.
Treatment for eczema often involves a multi-faceted approach, including the use of moisturizers to keep the skin hydrated, topical corticosteroids to reduce inflammation, and, in some cases, antihistamines to alleviate itching. Identifying and avoiding triggers such as certain soaps, fabrics, or foods can also play a crucial role in managing the condition. While there is currently no cure for eczema, ongoing advancements in research have led to the development of new therapies, including biologic medications that target specific components of the immune response, offering hope for those with moderate to severe cases.
Children's probiotics are dietary supplements specifically formulated to provide beneficial bacteria that support digestive health and the immune system in children. These probiotics contain various strains of live microorganisms, often including Lactobacillus and Bifidobacterium, which are known to help maintain a healthy balance of gut bacteria. The gut microbiome plays a crucial role in children's overall health, influencing their digestion, immune function, and even mood. Many parents turn to children's probiotics to help address issues like constipation, diarrhea, or colic, as well as to support their child’s immunity, especially during cold and flu season.
When selecting a children's probiotic, it’s essential to consider factors such as the specific strains included, the number of colony-forming units (CFUs), and whether it is tailored to your child's specific health needs. Probiotics can come in various forms, including powders, gummies, and liquids, making them easy to administer to little ones. However, it’s always advisable to consult a pediatrician before starting any new supplement regime for your child, as they can provide personalized recommendations based on the child's health history and current needs.
While the connection between probiotics and eczema is still being researched, some studies suggest that children’s probiotics may offer benefits in managing eczema symptoms. Probiotics are live bacteria that can help balance the gut microbiome, and some evidence indicates that they may enhance skin barrier function and reduce inflammation. For instance, certain strains of probiotics, such as Lactobacillus rhamnosus, have shown promise in small studies as a potential way to alleviate eczema symptoms, particularly in infants and young children.
However, it’s important to approach this option carefully and consult with a pediatrician before starting any new supplement regimen for eczema. Individual responses to probiotics can vary, and what works for one child may not work for another. Moreover, while probiotics can be part of a comprehensive approach to managing eczema, including topical treatments and dietary considerations, they shouldn't replace traditional medical advice or treatment plans. Additional research is necessary to determine definitive benefits, but probiotics could be considered as one possible complementary approach in a holistic strategy for managing eczema in children.
Based on user reviews, many individuals report seeing noticeable results for eczema within approximately two weeks of starting the supplement. For instance, one review mentions significant improvement in a child's eczema just two weeks into the regimen Read Review. Other users have observed benefits within just a few days, indicating that some may experience quicker results Read Review.
It's worth noting that while many users express satisfaction with the product after a short period, the overall experience can vary. Some individuals report that ongoing use is beneficial, suggesting that cumulative effects can contribute to continued improvement over time Read Review. Overall, if you're considering this supplement for eczema, starting with it for a couple of weeks would provide a good indication of its effectiveness for your specific situation.
The evidence surrounding probiotics, particularly Lactobacillus acidophilus and Lactobacillus rhamnosus, points towards their potential effectiveness in managing eczema. In animal studies, Lactobacillus acidophilus has shown to significantly reduce dermatitis symptoms by lowering immune cell infiltration and impacting inflammatory cytokines [1]. Similarly, meta-analyses and several randomized controlled trials indicate a positive correlation between probiotic use and decreased eczema symptoms in both children and adults [2], [3], [1]. Noteworthy results include Lactobacillus rhamnosus HN001, which has been linked to significant reductions in eczema prevalence among high-risk infants [18], [21].
However, while these findings are promising, the overall consistency and robustness of data remain variable. Some studies indicate that larger sample sizes are necessary to establish clearer conclusions about the efficacy of specific strains [2]. Moreover, factors like timing, dosage, and individual response variability complicate the ability to generalize findings across broader populations [19]. Thus, while certain probiotics show promise in alleviating eczema symptoms or potentially preventing them, ongoing research is essential to solidify their role in comprehensive eczema management.
Based on user reviews, many parents report significant improvements in their children's eczema after using the supplement. For example, one parent noted that their daughter's eczema showed noticeable improvement within two weeks of starting the product Read Review. Another user shared that their child's condition improved after just a few days, which highlights the potential for rapid effects Read Review.
Moreover, users appreciate how well their children enjoy taking the supplement, describing it as tasty and similar to candy, making adherence easier Read Review. Although many reviews reflect positive outcomes regarding eczema improvement, it's crucial to note that individual results can vary significantly. While some users experienced quick relief, others found that continued use yielded better, more sustained improvements over time Read Review. Overall, starting this supplement could be an effective approach for those struggling with eczema.
Users report varying experiences with the right dose of Children's Probiotics for treating eczema, but many indicate a positive correlation between the use of probiotics and an improvement in eczema symptoms. For example, one reviewer noted that their daughter's eczema improved significantly after two weeks of use (Read Review), while another user mentioned that their children's eczema showed considerable improvement after taking this supplement (Read Review). A recurring theme in the reviews is the ease of use and pleasant taste of the probiotics, contributing to consistent daily intake, which may enhance effectiveness.
Regarding age and dosage, one reviewer stated they began their children, who were four years old, on the probiotics and noticed a beneficial impact not just on eczema but also on their overall digestive health (Read Review). This suggests that users might find it effective to start probiotics at a young age, but exact dosage may vary based on individual tolerance and specific health needs. Overall, many reviewers express satisfaction with the improvements they observed, encouraging ongoing use of the probiotics for eczema treatment.
9
Greatly improved condition
1 people found this helpful
This product has greatly improved my daughter’s eczema. I’m not sure how it works, but the results were noticeable within two weeks, and we plan to keep using it for months.
7.5
Eczema relief seen
I bought a bottle and tried it. After taking it for a few days, my child's breath improved, and it also helped her eczema. Taking advantage of the current discount, I plan to buy again.
7.5
Child's eczema improvement
Introduced to me by a friend because her child's eczema improved after taking it for a while.
7.5
Good quality supplement
Yummy taste. Children like this flavour and chew it like candy. Great quality and easy to store, with no need to refrigerate. My child's eczema improved after taking this supplement. I like this product and will buy it again.
7.5
Good bowel effects
My children began taking this probiotic at four years of age, and it has positively impacted both their bowel movements and eczema.
7.5
Significant improvement
Children enjoy taking them, and their eczema has improved significantly.
9
Lactobacillus acidophilus helps eczema
Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model.
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
7
Weak evidence for eczema supplements
Clinical Efficacy of Nutritional Supplements in Atopic Dermatitis: Systematic Review.
We evaluated the effects of L-92—a paraprobiotic—on young children suffering from atopic dermatitis (AD) and food allergies. In a study of 59 children aged 10 months to 3 years, participants were given either L-92 or a placebo alongside standard AD treatment over 24 weeks.
The results showed a meaningful decrease in eczema severity in the L-92 group compared to baseline evaluations. Improvements in immune markers like TARC and total IgE levels were also documented. This indicates that L-92 may serve as an effective additional treatment for young children dealing with AD and food allergies.
9
Probiotic reduces eczema prevalence
Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
9
Lactobacillus rhamnosus reduces eczema prevalence
A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years.
We conducted a robust study using a double-blind randomized placebo-controlled trial to explore the impact of Lactobacillus rhamnosus HN001 on eczema in young children.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
8
Eczema prevention linked to probiotics
Probiotics and prebiotics in preventing food allergy and eczema.
We explored the effectiveness of probiotics, particularly Lactobacillus rhamnosus, in preventing eczema and food allergies. The research highlights that combining prenatal and postnatal probiotic treatment can significantly reduce eczema prevalence in infants up to 2 years old, with some benefits lasting until age 4. However, not all studies are consistent—while many show promising results, others do not find any significant effects. This suggests that the timing and specific strain of probiotics play a crucial role in their potential benefits.
References
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Weber I, Woolhiser E, Keime N, Wasvary M, Adelman MJ, et al. Clinical Efficacy of Nutritional Supplements in Atopic Dermatitis: Systematic Review. JMIR Dermatol. 2023;6:e40857. doi:10.2196/40857
Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, et al. Additive effect of L-92 on children with atopic dermatitis concomitant with food allergy. Asia Pac Allergy. 2019;9:e18. doi:10.5415/apallergy.2019.9.e18
Gulliver WP, Hutton AS, Ship N. Investigating the therapeutic potential of a probiotic in a clinical population with chronic hand dermatitis. Clin Cosmet Investig Dermatol. 2018;11:265. doi:10.2147/CCID.S164748
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Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, et al. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immunol. 2010;21:e386. doi:10.1111/j.1399-3038.2009.00958.x
Voigt J, Lele M. Lactobacillus rhamnosus Used in the Perinatal Period for the Prevention of Atopic Dermatitis in Infants: A Systematic Review and Meta-Analysis of Randomized Trials. Am J Clin Dermatol. 2022;23:801. doi:10.1007/s40257-022-00723-x
Nocerino R, Bedogni G, Carucci L, Cosenza L, Cozzolino T, et al. The Impact of Formula Choice for the Management of Pediatric Cow's Milk Allergy on the Occurrence of Other Allergic Manifestations: The Atopic March Cohort Study. J Pediatr. 2021;232:183. doi:10.1016/j.jpeds.2021.01.059
Schmidt RM, Pilmann Laursen R, Bruun S, Larnkjaer A, Mølgaard C, et al. Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial. Pediatr Allergy Immunol. 2019;30:335. doi:10.1111/pai.13018
Murphy R, Morgan XC, Wang XY, Wickens K, Purdie G, et al. Eczema-protective probiotic alters infant gut microbiome functional capacity but not composition: sub-sample analysis from a RCT. Benef Microbes. 2019;10:5. doi:10.3920/BM2017.0191
Wickens K, Barthow C, Mitchell EA, Kang J, van Zyl N, et al. Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatr Allergy Immunol. 2018;29:808. doi:10.1111/pai.12982
Wickens K, Barthow C, Mitchell EA, Stanley TV, Purdie G, et al. Maternal supplementation alone with Lactobacillus rhamnosus HN001 during pregnancy and breastfeeding does not reduce infant eczema. Pediatr Allergy Immunol. 2018;29:296. doi:10.1111/pai.12874
Berni Canani R, Di Costanzo M, Bedogni G, Amoroso A, Cosenza L, et al. Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial. J Allergy Clin Immunol. 2017;139:1906. doi:10.1016/j.jaci.2016.10.050
Marlow G, Han DY, Wickens K, Stanley T, Crane J, et al. Differential effects of two probiotics on the risks of eczema and atopy associated with single nucleotide polymorphisms to Toll-like receptors. Pediatr Allergy Immunol. 2015;26:262. doi:10.1111/pai.12371
Ismail IH, Boyle RJ, Mah LJ, Licciardi PV, Tang ML. Reduced neonatal regulatory T cell response to microbial stimuli associates with subsequent eczema in high-risk infants. Pediatr Allergy Immunol. 2014;25:674. doi:10.1111/pai.12303
Morgan AR, Han DY, Wickens K, Barthow C, Mitchell EA, et al. Differential modification of genetic susceptibility to childhood eczema by two probiotics. Clin Exp Allergy. 2014;44:1255. doi:10.1111/cea.12394
Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, et al. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?. Clin Exp Allergy. 2013;43:1048. doi:10.1111/cea.12154
Kuitunen M. Probiotics and prebiotics in preventing food allergy and eczema. Curr Opin Allergy Clin Immunol. 2013;13:280. doi:10.1097/ACI.0b013e328360ed66
Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130:1355. doi:10.1016/j.jaci.2012.09.003
Wickens K, Black P, Stanley TV, Mitchell E, Barthow C, et al. A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy. 2012;42:1071. doi:10.1111/j.1365-2222.2012.03975.x
Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, et al. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy. 2011;66:509. doi:10.1111/j.1398-9995.2010.02507.x
Puisto R, Gómez-Gallego C, Collado MC, Turta O, Isolauri E, et al. The Role of Infant Gut Microbiota Modulation by Perinatal Maternal Probiotic Intervention in Atopic Eczema Risk Reduction. Neonatology. 2025;122:84. doi:10.1159/000540075
Enomoto T, Sowa M, Nishimori K, Shimazu S, Yoshida A, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int. 2014;63:575. doi:10.2332/allergolint.13-OA-0683
Adjibade M, Vigneron L, Delvert R, Adel-Patient K, Divaret-Chauveau A, et al. Characteristics of infant formula consumed in the first months of life and allergy in the EDEN mother-child cohort. Matern Child Nutr. 2024;20:e13673. doi:10.1111/mcn.13673
Kim HK, Rutten NB, Besseling-van der Vaart I, Niers LE, Choi YH, et al. Probiotic supplementation influences faecal short chain fatty acids in infants at high risk for eczema. Benef Microbes. 2015;6:783. doi:10.3920/BM2015.0056
Niers L, Martín R, Rijkers G, Sengers F, Timmerman H, et al. The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy. 2009;64:1349. doi:10.1111/j.1398-9995.2009.02021.x
Wickens K, Black PN, Stanley TV, Mitchell E, Fitzharris P, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2008;122:788. doi:10.1016/j.jaci.2008.07.011
Kirjavainen PV, Arvola T, Salminen SJ, Isolauri E. Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?. Gut. 2002;51:51.
Isolauri E, Arvola T, Sütas Y, Moilanen E, Salminen S. Probiotics in the management of atopic eczema. Clin Exp Allergy. 2000;30:1604.