We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
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9
Lactobacillus L-92 shows eczema benefits
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis.
We examined the effects of Lactobacillus rhamnosus HN001 on eczema prevention among children with genetic predispositions. In our double-blind, randomized, placebo-controlled study involving 331 children, we discovered that those with specific high-risk gene variants experienced lower eczema rates when treated with HN001, compared to those receiving a placebo. This suggests Lactobacillus rhamnosus might be particularly beneficial for children at greater genetic risk of eczema and may even influence the severity of eczema and related allergic conditions.
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Most Useful Reviews
10
No more itching
7 people found this helpful
Cured eczema. My 6-year-old was suffering from very itchy eczema spots. A friend suggested this product, and it worked remarkably! His skin is now clear with no complaints of itching. I will undoubtedly be a repeat customer!
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7.5
Some relief
2 people found this helpful
Eczema relief. My son suffers from severe eczema. We've tried everything and consulted several doctors. While these did not fully clear it, they certainly helped. His skin is much clearer, and he has experienced some relief. I would recommend this product.
We conducted a study to see if giving probiotics to mothers during pregnancy and breastfeeding could help reduce eczema in infants at risk. This double-blind, placebo-controlled trial involved 241 mother-infant pairs, where mothers were given either specific probiotics or a placebo.
Our findings showed that infants whose mothers took Lactobacillus rhamnosus and Bifidobacterium longum had a significantly lower risk of developing eczema in their first two years. This suggests that probiotics can be a safe and effective preventive measure for high-risk infants.
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9
Lactobacillus acidophilus helps eczema
Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model.
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.
Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
Read More
9
Lactobacillus L-92 shows eczema benefits
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis.
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
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9
Lactobacillus rhamnosus reduces eczema prevalence
A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years.
We conducted a robust study using a double-blind randomized placebo-controlled trial to explore the impact of Lactobacillus rhamnosus HN001 on eczema in young children.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
Cured eczema. My 6-year-old was suffering from very itchy eczema spots. A friend suggested this product, and it worked remarkably! His skin is now clear with no complaints of itching. I will undoubtedly be a repeat customer!
Read More
7.5
Some relief
2 people found this helpful
Eczema relief. My son suffers from severe eczema. We've tried everything and consulted several doctors. While these did not fully clear it, they certainly helped. His skin is much clearer, and he has experienced some relief. I would recommend this product.
Read More
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References
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Ismail IH, Boyle RJ, Mah LJ, Licciardi PV, Tang ML. Reduced neonatal regulatory T cell response to microbial stimuli associates with subsequent eczema in high-risk infants. Pediatr Allergy Immunol. 2014;25:674. 10.1111/pai.12303
Morgan AR, Han DY, Wickens K, Barthow C, Mitchell EA, et al. Differential modification of genetic susceptibility to childhood eczema by two probiotics. Clin Exp Allergy. 2014;44:1255. 10.1111/cea.12394
Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, et al. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?. Clin Exp Allergy. 2013;43:1048. 10.1111/cea.12154
Kuitunen M. Probiotics and prebiotics in preventing food allergy and eczema. Curr Opin Allergy Clin Immunol. 2013;13:280. 10.1097/ACI.0b013e328360ed66
Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130:1355. 10.1016/j.jaci.2012.09.003
Wickens K, Black P, Stanley TV, Mitchell E, Barthow C, et al. A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy. 2012;42:1071. 10.1111/j.1365-2222.2012.03975.x
Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, et al. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy. 2011;66:509. 10.1111/j.1398-9995.2010.02507.x
Puisto R, Gómez-Gallego C, Collado MC, Turta O, Isolauri E, et al. The Role of Infant Gut Microbiota Modulation by Perinatal Maternal Probiotic Intervention in Atopic Eczema Risk Reduction. Neonatology. 2025;122:84. 10.1159/000540075
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Kim HK, Rutten NB, Besseling-van der Vaart I, Niers LE, Choi YH, et al. Probiotic supplementation influences faecal short chain fatty acids in infants at high risk for eczema. Benef Microbes. 2015;6:783. 10.3920/BM2015.0056
Niers L, Martín R, Rijkers G, Sengers F, Timmerman H, et al. The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy. 2009;64:1349. 10.1111/j.1398-9995.2009.02021.x
Wickens K, Black PN, Stanley TV, Mitchell E, Fitzharris P, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol. 2008;122:788. 10.1016/j.jaci.2008.07.011
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