Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.2
USERS' SCORE
Good
Based on 12 Reviews
8.3
Supplement Facts
Serving Size: 1 Spray (Approx. 0.41 ml)
Amount Per Serving
%DV
Vitamin B12(as Methylcobalamin from Saccharomyces cerevisiae)
500 mcg
20,833%
Certified Organic Food BlendOrganic Beet (root), Organic Carrot (root), Organic Spinach (leaf), Organic Broccoli (flower & stem), Organic Tomato (fruit), Organic Kale (leaf), Organic Cabbage (leaf), Organic Parsley (leaf), Organic Brussels Sprout (leaf), Organic Green Bell Pepper (fruit), Organic Cucumber (gourd), Organic Celery (stalk), Organic Garlic (bulb), Organic Ginger (root), Organic Onion (root), Organic Cauliflower (flower & stem), Organic Asparagus (flower & stem), Organic Strawberry (fruit), Organic Cherry (fruit), Organic Blackberry (fruit), Organic Blueberry (fruit), Organic Raspberry (fruit)
2 mg
+
Top Medical Research Studies
9
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Read More
8
We investigated the potential of cyanocobalamin, or Vitamin B12, as a treatment for skin inflammation using a cutting-edge transdermal delivery system. The research focused on microneedle patches that effectively deliver this antioxidant form of Vitamin B12 into the skin.
Our findings highlighted reduced inflammation and damage in skin models, indicated by decreased cytokine levels and less oxidative stress. This approach may present a new, cost-effective method to enhance skin care for patients dealing with chronic inflammatory conditions.
However, it's important to note that while the results are promising, further studies are needed for broader applications.
Our findings highlighted reduced inflammation and damage in skin models, indicated by decreased cytokine levels and less oxidative stress. This approach may present a new, cost-effective method to enhance skin care for patients dealing with chronic inflammatory conditions.
However, it's important to note that while the results are promising, further studies are needed for broader applications.
Read More
8
We aimed to examine whether bread fermented with UFMG A-905 could help prevent allergic asthma. In our study, we created three types of bread and tested them on mice sensitized to allergens.
The results showed that the UFMG A-905 fermented bread could significantly reduce some asthma-like symptoms, particularly when paired with microcapsules containing live yeast.
Overall, this suggests that incorporating UFMG A-905 into food could be a promising approach for managing allergies.
The results showed that the UFMG A-905 fermented bread could significantly reduce some asthma-like symptoms, particularly when paired with microcapsules containing live yeast.
Overall, this suggests that incorporating UFMG A-905 into food could be a promising approach for managing allergies.
Read More
Most Useful Reviews
9
No allergies noted
196 people found this helpful
The impression of these vitamins is positive. The vitamin B12 comes in a convenient spray format, making it easy to administer to children without injections or pills. As I have low hemoglobin and don't consume meat, I found these vitamins helpful. There were no allergies or gastrointestinal issues, and my hair stopped falling out after a month. Chronic fatigue also disappeared.
Read More
9
No allergies noted
9 people found this helpful
This spray was recommended by a hematologist for my daughter and me to combat anaemia. It is easy to use, and my child willingly opens her mouth for it; the pleasant taste caused no allergies. Taken in the morning, it significantly boosts energy, allowing my child to expend energy throughout the day. Blood counts improved after including this B12.
Read More
9
No allergies noted
1 people found this helpful
I started taking vitamin B12 for latent anaemia treatment, along with my husband. We take one spray every morning. I hope this natural vitamin helps, and I'm pleased that I have not experienced any allergies. It has an intensely raspberry taste, which I enjoy, and I have not observed any side effects yet.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.2
- All Researches
9
We examined how a combined probiotic treatment affects children with food allergies. The study included 92 kids with both skin and gastrointestinal symptoms. Those who took the probiotic showed a significant drop in their allergy symptoms over 21 days, including a decrease in inflammation markers.
Specifically, children in the main group had improved skin and gut symptoms, along with notable reductions in IgE levels compared to those who didn’t receive the treatment. While symptoms increased slightly after the treatment stopped, they remained less severe than before, demonstrating the potential benefits of B12 in managing allergies.
Specifically, children in the main group had improved skin and gut symptoms, along with notable reductions in IgE levels compared to those who didn’t receive the treatment. While symptoms increased slightly after the treatment stopped, they remained less severe than before, demonstrating the potential benefits of B12 in managing allergies.
Read More
9
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Read More
8
We investigated the potential of cyanocobalamin, or Vitamin B12, as a treatment for skin inflammation using a cutting-edge transdermal delivery system. The research focused on microneedle patches that effectively deliver this antioxidant form of Vitamin B12 into the skin.
Our findings highlighted reduced inflammation and damage in skin models, indicated by decreased cytokine levels and less oxidative stress. This approach may present a new, cost-effective method to enhance skin care for patients dealing with chronic inflammatory conditions.
However, it's important to note that while the results are promising, further studies are needed for broader applications.
Our findings highlighted reduced inflammation and damage in skin models, indicated by decreased cytokine levels and less oxidative stress. This approach may present a new, cost-effective method to enhance skin care for patients dealing with chronic inflammatory conditions.
However, it's important to note that while the results are promising, further studies are needed for broader applications.
Read More
8
We investigated how EpiCor, a yeast-derived postbiotic, influences cold and flu symptoms in children aged 4-12. Two hundred fifty-six kids participated in a randomized, controlled trial over 84 days during the flu season.
Those receiving EpiCor showed significantly less symptom severity and reduced use of cold medications compared to the placebo group.
This suggests EpiCor is a promising option to boost immune function and reduce illness in school-aged children without undesirable side effects.
Those receiving EpiCor showed significantly less symptom severity and reduced use of cold medications compared to the placebo group.
This suggests EpiCor is a promising option to boost immune function and reduce illness in school-aged children without undesirable side effects.
Read More
8
We aimed to examine whether bread fermented with UFMG A-905 could help prevent allergic asthma. In our study, we created three types of bread and tested them on mice sensitized to allergens.
The results showed that the UFMG A-905 fermented bread could significantly reduce some asthma-like symptoms, particularly when paired with microcapsules containing live yeast.
Overall, this suggests that incorporating UFMG A-905 into food could be a promising approach for managing allergies.
The results showed that the UFMG A-905 fermented bread could significantly reduce some asthma-like symptoms, particularly when paired with microcapsules containing live yeast.
Overall, this suggests that incorporating UFMG A-905 into food could be a promising approach for managing allergies.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
No allergies noted
196 people found this helpful
The impression of these vitamins is positive. The vitamin B12 comes in a convenient spray format, making it easy to administer to children without injections or pills. As I have low hemoglobin and don't consume meat, I found these vitamins helpful. There were no allergies or gastrointestinal issues, and my hair stopped falling out after a month. Chronic fatigue also disappeared.
Read More
9
No allergies noted
9 people found this helpful
This spray was recommended by a hematologist for my daughter and me to combat anaemia. It is easy to use, and my child willingly opens her mouth for it; the pleasant taste caused no allergies. Taken in the morning, it significantly boosts energy, allowing my child to expend energy throughout the day. Blood counts improved after including this B12.
Read More
9
No allergies noted
1 people found this helpful
I started taking vitamin B12 for latent anaemia treatment, along with my husband. We take one spray every morning. I hope this natural vitamin helps, and I'm pleased that I have not experienced any allergies. It has an intensely raspberry taste, which I enjoy, and I have not observed any side effects yet.
Read More
9
No allergies noted
A very good spray that did not cause any allergies.
Read More
9
No allergies noted
I purchased this B12 for my daughters. I give one spray daily, and according to test results, B12 levels have increased significantly. My daughter feels less tired and has more energy, and there have been no allergies.
Read More
Frequently Asked Questions
9
No allergies noted
196 people found this helpful
The impression of these vitamins is positive. The vitamin B12 comes in a convenient spray format, making it easy to administer to children without injections or pills. As I have low hemoglobin and don't consume meat, I found these vitamins helpful. There were no allergies or gastrointestinal issues, and my hair stopped falling out after a month. Chronic fatigue also disappeared.
9
No allergies noted
I purchased this B12 for my daughters. I give one spray daily, and according to test results, B12 levels have increased significantly. My daughter feels less tired and has more energy, and there have been no allergies.
2
Slight allergy noted
B12 is good, but it is too early to comment on the effects as the doctor prescribed two doses, and I experienced a slight allergy. I have not yet had tests done.
0
Contains irritants
4 people found this helpful
It contains sweetener, which caused me allergies. Unlike raw B12 capsules, this vitamin has sweeteners that may cause discomfort in sensitive individuals. I don't understand why vitamins now include sweeteners (like stevia, xylitol, mannitol), preservatives (like potassium sorbate), and additives (such as magnesium stearate), which can be harmful to health.
0
Allergy noted
Unfortunately, this product did not suit my child due to an allergy.
9
No allergies noted
9 people found this helpful
This spray was recommended by a hematologist for my daughter and me to combat anaemia. It is easy to use, and my child willingly opens her mouth for it; the pleasant taste caused no allergies. Taken in the morning, it significantly boosts energy, allowing my child to expend energy throughout the day. Blood counts improved after including this B12.
0
Allergen present
2 people found this helpful
I was unaware that this spray contains ginger, to which I am allergic. However, the taste is quite pleasant.
9
No allergies noted
1 people found this helpful
I started taking vitamin B12 for latent anaemia treatment, along with my husband. We take one spray every morning. I hope this natural vitamin helps, and I'm pleased that I have not experienced any allergies. It has an intensely raspberry taste, which I enjoy, and I have not observed any side effects yet.
9
We examined how a combined probiotic treatment affects children with food allergies. The study included 92 kids with both skin and gastrointestinal symptoms. Those who took the probiotic showed a significant drop in their allergy symptoms over 21 days, including a decrease in inflammation markers.
Specifically, children in the main group had improved skin and gut symptoms, along with notable reductions in IgE levels compared to those who didn’t receive the treatment. While symptoms increased slightly after the treatment stopped, they remained less severe than before, demonstrating the potential benefits of B12 in managing allergies.
Specifically, children in the main group had improved skin and gut symptoms, along with notable reductions in IgE levels compared to those who didn’t receive the treatment. While symptoms increased slightly after the treatment stopped, they remained less severe than before, demonstrating the potential benefits of B12 in managing allergies.
9
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.
Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
7
We explored a group of 29 patients who were referred to three allergy centers in the UK due to suspected vitamin B12 hypersensitivity (VB12H). Over the period from 2014 to 2022, these patients underwent various tests, including skin prick tests and drug provocation tests. The aim was to understand how vitamin B12 treatment relates to allergies and to develop a reliable method for assessing hypersensitivity.
Among the patients, 62% displayed immediate hypersensitivity reactions, with some experiencing severe anaphylaxis to vitamin B12 forms. Interestingly, we found that some patients who were sensitized to a specific type of vitamin B12 could tolerate another form. This indicates that not all vitamin B12 treatments may cause problems for everyone. However, confirmed cases of VB12H are considered to be quite rare.
Overall, while we identified individual cases where vitamin B12 treatment provoked allergic responses, the evidence suggests that vitamin B12 hypersensitivity is uncommon. This nuances the discussions around vitamin B12 treatment face since adverse reactions are not widespread. Our proposed evaluation protocol includes skin testing and considerations for allergies to related substances, such as polyethylene glycol.
Therefore, while there is an observable connection between vitamin B12 and allergic reactions in a small subset of individuals, the study indicates that treatment for vitamin B12 deficiency remains generally safe for most individuals.
Among the patients, 62% displayed immediate hypersensitivity reactions, with some experiencing severe anaphylaxis to vitamin B12 forms. Interestingly, we found that some patients who were sensitized to a specific type of vitamin B12 could tolerate another form. This indicates that not all vitamin B12 treatments may cause problems for everyone. However, confirmed cases of VB12H are considered to be quite rare.
Overall, while we identified individual cases where vitamin B12 treatment provoked allergic responses, the evidence suggests that vitamin B12 hypersensitivity is uncommon. This nuances the discussions around vitamin B12 treatment face since adverse reactions are not widespread. Our proposed evaluation protocol includes skin testing and considerations for allergies to related substances, such as polyethylene glycol.
Therefore, while there is an observable connection between vitamin B12 and allergic reactions in a small subset of individuals, the study indicates that treatment for vitamin B12 deficiency remains generally safe for most individuals.
References
- Guillot AJ, Martínez-Navarrete M, Giner RM, Recio MC, Santos HA, et al. Cyanocobalamin-loaded dissolving microneedles diminish skin inflammation in vivo. J Control Release. 2024;375:537. 10.1016/j.jconrel.2024.09.032
- Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. 10.33029/0042-8833-2023-92-3-79-86
- Sandy CM, Guimarães CC, Fonseca VMB, Nicoli JR, Martins FS, et al. Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice. Benef Microbes. 2024;16:125. 10.1163/18762891-bja00044
- Singh RG, Garcia-Campayo V, Green JB, Paton N, Saunders JD, et al. Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial. Pediatr Res. 2024;96:1739. 10.1038/s41390-024-03331-z
- Calazans APCT, Milani TMS, Prata AS, Clerici MTPS, Nicoli JR, et al. A Functional Bread Fermented with UFMG A-905 Prevents Allergic Asthma in Mice. Curr Dev Nutr. 2024;8:102142. 10.1016/j.cdnut.2024.102142
- El Rhermoul FZ, Mustafa A, Wagner A, Nakonechna A, Kayode OS, et al. Vitamin B Hypersensitivity: A Retrospective Multicenter Study. J Allergy Clin Immunol Pract. 2024;12:699. 10.1016/j.jaip.2023.10.037
