This probiotic is awesome! I've been using it off and on for about 2 years now, but had previously purchased it from a local vitamin store. I had started taking this 2 years ago to help with constipation & slow digestion issues. At the time, I was experiencing withdrawal symptoms after stopping long term use of an herbal supplement called valerian. The withdrawal symptoms I had were high heart rate, anxiety, panic attacks, depression and insomnia. When I first started taking this probiotic, I noticed it helped me feel more calm & helped me sleep better. I researched online and found that probiotics help calm the nervous system and that's definitely true with this probiotic. To help me with sleep, I find it helpful to take this with a glass of wine on an empty stomach in the evening before dinner. When I do that, I pretty much sleep straight through the night! Also I discovered it helps lower my high blood pressure. Normally I get white coat syndrome where my blood pressure goes up when I have a doctors appointment, even though I take blood pressure medicine. After using this probiotic, my blood pressure is lower & I have much more normal readings when I see my doctor. Also, one time at work I was already very busy & stressed out when I got some news that caused me to feel panicked and more stressed out and I started getting a Headache. Luckily I had my bottle of this probiotic with me and took a pill. After about 1-2 hours, I started to feel more calm and my Headache was alleviated! I'm so glad I found this probiotic and will continue to use it