Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.7
USERS' SCORE
Good
Based on 48 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Organic Turmeric BlendOrganic Turmeric Root Extract standardized to 95% curcuminoids, Organic Fermented Turmeric Root (blend yielding 100 mg curcuminoids)
553 mg
+
Organic Fermented Ginger Root
50 mg
+
Organic Black Pepper Fruit Extract
7 mg
+
Probiotic Blend Bifidobacterium lactis Bl-04Lactobacillus acidophilus La-14
4 mg
+
Top Medical Research Studies
9
In a well-structured study involving 101 adults suffering from knee osteoarthritis, we explored the effects of curcumin, a compound derived from turmeric, on knee pain. Participants were randomly assigned to receive either 500 mg of a standardized curcumin extract, Curcugen, twice daily, or a placebo for eight weeks, allowing for a clear comparison of its effectiveness.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
Read More
9
We sought to determine the effectiveness of Curcuma longa extract, commonly known as turmeric, in alleviating knee pain associated with osteoarthritis. Our investigation focused on randomized controlled trials that compared turmeric extract with placebo, analyzing data from notable databases like PubMed and Cochrane Library through April 2021.
In total, we reviewed 10 trials encompassing 783 patients. The outcomes of our analysis were quite promising. We found that patients taking Curcuma longa experienced significantly greater relief from pain and improved overall function compared to those given a placebo. Notably, the measures used to assess pain and functionality showed results that exceeded the minimum clinically important differences, meaning that the improvements were not just statistically significant but also meaningful in real life.
This evidence suggests that incorporating turmeric extract into treatment plans may offer substantial benefits for those suffering from knee osteoarthritis. However, we must acknowledge that the studies we reviewed exhibited some variability, indicating a need for further high-quality research with larger participant groups to corroborate our findings on turmeric’s effectiveness.
In total, we reviewed 10 trials encompassing 783 patients. The outcomes of our analysis were quite promising. We found that patients taking Curcuma longa experienced significantly greater relief from pain and improved overall function compared to those given a placebo. Notably, the measures used to assess pain and functionality showed results that exceeded the minimum clinically important differences, meaning that the improvements were not just statistically significant but also meaningful in real life.
This evidence suggests that incorporating turmeric extract into treatment plans may offer substantial benefits for those suffering from knee osteoarthritis. However, we must acknowledge that the studies we reviewed exhibited some variability, indicating a need for further high-quality research with larger participant groups to corroborate our findings on turmeric’s effectiveness.
Read More
9.5
We aimed to understand how curcumin, a compound found in turmeric, impacts knee pain in individuals suffering from osteoarthritis (OA). Using various databases, we gathered and analyzed data from multiple meta-analyses that included randomized controlled trials focused on curcumin's effects on OA symptoms up to September 2023.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
Read More
Most Useful Reviews
9
Pain-free result
18 people found this helpful
The inflammation in my knees has disappeared! After switching from CVS brand to this, I was no longer limping after only a week. I had previously taken Glucosamine, but it ceased to work. I'm thrilled to be free from knee pain and wish I'd discovered this remedy sooner.
Read More
9
Disappeared symptoms
9 people found this helpful
After taking one capsule daily for a month, my trigger finger symptoms vanished, and my knee pain improved substantially. I've had no side effects, and I will continue taking this turmeric daily as it has made a noticeable difference in my knee condition.
Read More
9
Significant improvement
8 people found this helpful
I suffered from rheumatoid arthritis, but after a month of this supplement, my inflammation and knee pain improved dramatically: my SOE dropped from 53 to 26. I often forget I have joint issues now. It's a powerful anti-inflammatory.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.7
- All Researches
9.5
We aimed to understand how curcumin, a compound found in turmeric, impacts knee pain in individuals suffering from osteoarthritis (OA). Using various databases, we gathered and analyzed data from multiple meta-analyses that included randomized controlled trials focused on curcumin's effects on OA symptoms up to September 2023.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
The results clearly demonstrated that curcumin supplementation substantially alleviates pain, as reflected in reduced scores on several pain measurement scales. These included the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) for pain, function, and stiffness.
Statistically significant improvements were observed across the board, highlighting that curcumin not only helps in reducing pain but also enhances joint function and decreases stiffness. This collectively suggests that curcumin can be an effective supplement for those managing knee OA, possibly minimizing the need for other medications.
Overall, our findings support the benefits of incorporating curcumin into treatment plans for osteoarthritis, offering a promising path for pain relief and improved mobility.
Read More
9
Topical curcumin gel effectiveness
We conducted a study to explore the effectiveness of a unique topical gel infused with curcumin, a key ingredient in turmeric, for treating knee osteoarthritis. This innovative gel utilizes a self-nano-emulsifying organogel system, which allows for better delivery of curcumin, a compound known for its challenging solubility and stability issues.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
Read More
9
Turmeric improves knee osteoarthritis
Our study focused on the impact of a specific combination of polyphenolic supplements, including turmeric, on knee pain for individuals with osteoarthritis. We conducted a randomized controlled trial with 60 participants, half of whom received the polyphenolic supplement featuring turmeric, rosemary extract, and resveratrol, while the other half received a placebo.
Over the course of 12 weeks, those taking the polyphenol supplement reported significantly reduced pain levels and improved physical functionality. The data was collected using validated questionnaires, demonstrating clearer benefits in this group compared to those on the placebo.
Notably, we observed that the polyphenol supplement also helped reduce systemic inflammation, which could be a key factor in easing knee pain. This suggests that turmeric, as part of the supplement, may play a beneficial role in managing not just pain, but also the overall quality of life for those suffering from knee osteoarthritis.
Over the course of 12 weeks, those taking the polyphenol supplement reported significantly reduced pain levels and improved physical functionality. The data was collected using validated questionnaires, demonstrating clearer benefits in this group compared to those on the placebo.
Notably, we observed that the polyphenol supplement also helped reduce systemic inflammation, which could be a key factor in easing knee pain. This suggests that turmeric, as part of the supplement, may play a beneficial role in managing not just pain, but also the overall quality of life for those suffering from knee osteoarthritis.
Read More
9
We studied the effects of curcumin, a compound in turmeric, alongside swimming to see how this combination could help alleviate knee pain caused by osteoarthritis (OA). In our research with rats, we set up five groups, with some getting the treatment and others serving as a control.
After injecting a substance that induces OA, we began a daily swimming regimen for certain groups and provided them with oral curcumin over four weeks. This combination proved to be the most effective in reducing pain and stiffness in the joints.
Not only did we notice improvement in the rats' discomfort, but there were also positive changes seen in their joint health when examined under a microscope. We observed a decrease in markers of inflammation, suggesting that the dual treatment could provide a more effective path for managing knee pain in osteoarthritis patients.
Overall, this research highlights the potential benefits of combining curcumin with physical activity like swimming for easing knee pain due to OA.
After injecting a substance that induces OA, we began a daily swimming regimen for certain groups and provided them with oral curcumin over four weeks. This combination proved to be the most effective in reducing pain and stiffness in the joints.
Not only did we notice improvement in the rats' discomfort, but there were also positive changes seen in their joint health when examined under a microscope. We observed a decrease in markers of inflammation, suggesting that the dual treatment could provide a more effective path for managing knee pain in osteoarthritis patients.
Overall, this research highlights the potential benefits of combining curcumin with physical activity like swimming for easing knee pain due to OA.
Read More
9
In our analysis, we investigated how a blend of several natural ingredients, including turmeric (CurQlife, curcumin), might alleviate knee pain in individuals suffering from osteoarthritis. Our study focused on the effects of this combination of nutraceuticals, known as Clagen™, which also includes native type 2 collagen, hyaluronic acid, and other supportive components.
We enrolled 100 patients with knee osteoarthritis and monitored their progress over two months. At the end of this period, we noted a significant reduction in pain levels, as evidenced by improved Visual Analog Scale (VAS) scores. Additionally, there were noticeable enhancements in the range of motion and overall quality of life for the participants.
While turmeric was part of the combination, we can't isolate its specific effects from those of the other ingredients. Nonetheless, this study suggests that combining these natural substances may offer a beneficial strategy for managing knee pain, potentially reducing the need for traditional pain medications like NSAIDs in the long run. However, further long-term studies are needed to confirm these findings.
We enrolled 100 patients with knee osteoarthritis and monitored their progress over two months. At the end of this period, we noted a significant reduction in pain levels, as evidenced by improved Visual Analog Scale (VAS) scores. Additionally, there were noticeable enhancements in the range of motion and overall quality of life for the participants.
While turmeric was part of the combination, we can't isolate its specific effects from those of the other ingredients. Nonetheless, this study suggests that combining these natural substances may offer a beneficial strategy for managing knee pain, potentially reducing the need for traditional pain medications like NSAIDs in the long run. However, further long-term studies are needed to confirm these findings.
Read More
User Reviews
USERS' SCORE
Good
Based on 48 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain-free result
18 people found this helpful
The inflammation in my knees has disappeared! After switching from CVS brand to this, I was no longer limping after only a week. I had previously taken Glucosamine, but it ceased to work. I'm thrilled to be free from knee pain and wish I'd discovered this remedy sooner.
Read More
9
Disappeared symptoms
9 people found this helpful
After taking one capsule daily for a month, my trigger finger symptoms vanished, and my knee pain improved substantially. I've had no side effects, and I will continue taking this turmeric daily as it has made a noticeable difference in my knee condition.
Read More
9
Significant improvement
8 people found this helpful
I suffered from rheumatoid arthritis, but after a month of this supplement, my inflammation and knee pain improved dramatically: my SOE dropped from 53 to 26. I often forget I have joint issues now. It's a powerful anti-inflammatory.
Read More
9
Aches gone
8 people found this helpful
After contracting COVID, I faced inflammatory symptoms, including knee pain. However, within 24 hours of taking this turmeric supplement, my aches disappeared. My husband also noticed a significant reduction in his knee pain after a few days. This product has been excellent for us!
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9
Gout relief
7 people found this helpful
I was suffering from gout and discovered that this product alleviated my knee pain effectively. I highly recommend it as it has reduced my pain and improved my overall condition.
Read More
Frequently Asked Questions
9
Aches gone
8 people found this helpful
After contracting COVID, I faced inflammatory symptoms, including knee pain. However, within 24 hours of taking this turmeric supplement, my aches disappeared. My husband also noticed a significant reduction in his knee pain after a few days. This product has been excellent for us!
9
Disappeared symptoms
9 people found this helpful
After taking one capsule daily for a month, my trigger finger symptoms vanished, and my knee pain improved substantially. I've had no side effects, and I will continue taking this turmeric daily as it has made a noticeable difference in my knee condition.
9
Pain-free result
18 people found this helpful
The inflammation in my knees has disappeared! After switching from CVS brand to this, I was no longer limping after only a week. I had previously taken Glucosamine, but it ceased to work. I'm thrilled to be free from knee pain and wish I'd discovered this remedy sooner.
7.5
Pain reduction
5 people found this helpful
After trying many supplements, I found this one to be the best. I noticed a significant reduction in my knee pain and lower back pain within a couple of days. I was impressed with the results and highly recommend it.
9
Improved knee mobility
4 people found this helpful
This product helps with joint pain and boosts immunity. I initially doubted the taste (curcumin + black pepper), but I enjoy it now. After two weeks, I can walk more than 6000 steps without knee pain, up from 3000.
9
Significant improvement
8 people found this helpful
I suffered from rheumatoid arthritis, but after a month of this supplement, my inflammation and knee pain improved dramatically: my SOE dropped from 53 to 26. I often forget I have joint issues now. It's a powerful anti-inflammatory.
7.5
Effective remedy
An excellent remedy for knee pain when combined with Boswellia.
9
Pain-free joints
1 people found this helpful
The best turmeric! I regularly consume this quality product, which has organic and useful ingredients. My joints are in good shape and my knee pain has disappeared. It has a neutral turmeric taste, and I take it alongside omega 3, lecithin, and multivitamins for overall support at age 34.
8
We delved into how turmeric might help alleviate knee pain associated with osteoarthritis (OA), a condition affecting a significant number of adults. The study we reviewed was a comprehensive systematic review and meta-analysis involving a total of ten randomized controlled trials with 786 participants.
The main focus was on evaluating the impact of turmeric on pain relief, specifically through the Visual Analog Scale (VAS) for pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score. Turmeric showed promise by significantly improving pain scores compared to a placebo and demonstrated effects comparable to those of nonsteroidal anti-inflammatory drugs (NSAIDs).
With results highlighting an improvement in pain levels, both lower and higher dosages of turmeric were effective when compared to placebo. However, we also noted that the limitations and variability in the studies suggest that further research would be beneficial to determine the best dosages and methods for using turmeric as a treatment option for knee OA.
Overall, the findings suggest that turmeric could be a valuable alternative for those seeking relief from knee pain due to osteoarthritis, standing out against standard options like NSAIDs while having a potentially fewer side effects.
The main focus was on evaluating the impact of turmeric on pain relief, specifically through the Visual Analog Scale (VAS) for pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score. Turmeric showed promise by significantly improving pain scores compared to a placebo and demonstrated effects comparable to those of nonsteroidal anti-inflammatory drugs (NSAIDs).
With results highlighting an improvement in pain levels, both lower and higher dosages of turmeric were effective when compared to placebo. However, we also noted that the limitations and variability in the studies suggest that further research would be beneficial to determine the best dosages and methods for using turmeric as a treatment option for knee OA.
Overall, the findings suggest that turmeric could be a valuable alternative for those seeking relief from knee pain due to osteoarthritis, standing out against standard options like NSAIDs while having a potentially fewer side effects.
8
We assessed the effectiveness of turmeric, particularly its active ingredient curcumin, in alleviating knee pain associated with osteoarthritis (OA). This analysis included twelve studies, which involved a total of 1,438 participants, comparing those taking curcumin against placebo groups.
The findings revealed significant improvements in both pain and function for those receiving curcumin compared to the placebo group. However, there was no notable difference when curcumin was compared with other treatments like nonsteroidal anti-inflammatory drugs or paracetamol, which are commonly used for pain relief.
Additionally, we found that taking curcumin resulted in a favorable impact on inflammation markers, which can be an important aspect of managing OA symptoms. It's worth highlighting that while turmeric shows promising benefits for knee pain, further studies are needed to explore the effects of other supplements, like omega-3 and vitamin D.
The findings revealed significant improvements in both pain and function for those receiving curcumin compared to the placebo group. However, there was no notable difference when curcumin was compared with other treatments like nonsteroidal anti-inflammatory drugs or paracetamol, which are commonly used for pain relief.
Additionally, we found that taking curcumin resulted in a favorable impact on inflammation markers, which can be an important aspect of managing OA symptoms. It's worth highlighting that while turmeric shows promising benefits for knee pain, further studies are needed to explore the effects of other supplements, like omega-3 and vitamin D.
8
We systematically reviewed several randomized controlled trials that focused on curcumin's effects on knee pain due to osteoarthritis. Our aim was to understand how low and high doses of curcumin might aid in pain relief and improve function compared to traditional non-steroidal anti-inflammatory drugs (NSAIDs). We gathered data from a variety of trusted medical databases, looking at studies published up until June 2021.
Our analysis included eleven studies with a total of 1,258 participants suffering from primary knee osteoarthritis. We discovered that curcuminoids, the active compounds in turmeric, provided meaningful pain relief, as shown by improvements in visual analogue scale (VAS) scores and Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores when compared to other treatments.
Interestingly, we did not find significant differences in pain relief or adverse events (AEs) between high-dose (1,000 mg or more daily) and low-dose (less than 1,000 mg daily) curcumin treatments. However, curcuminoids were found to be more effective than NSAIDs in managing knee pain. While some studies reported higher adverse events in the NSAID group, only one study confirmed this finding was statistically significant.
Overall, our findings suggest that curcumin could be a beneficial supplement for those dealing with knee osteoarthritis, potentially serving as a supportive treatment alongside NSAIDs.
Our analysis included eleven studies with a total of 1,258 participants suffering from primary knee osteoarthritis. We discovered that curcuminoids, the active compounds in turmeric, provided meaningful pain relief, as shown by improvements in visual analogue scale (VAS) scores and Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores when compared to other treatments.
Interestingly, we did not find significant differences in pain relief or adverse events (AEs) between high-dose (1,000 mg or more daily) and low-dose (less than 1,000 mg daily) curcumin treatments. However, curcuminoids were found to be more effective than NSAIDs in managing knee pain. While some studies reported higher adverse events in the NSAID group, only one study confirmed this finding was statistically significant.
Overall, our findings suggest that curcumin could be a beneficial supplement for those dealing with knee osteoarthritis, potentially serving as a supportive treatment alongside NSAIDs.
8
We investigated how curcumin, a compound found in turmeric, along with vitamin D, could affect knee pain and the progression of knee osteoarthritis (OA) in a specific rat model. In this study, male Wistar rats were divided into five groups: a control group, a group receiving curcumin, a group receiving vitamin D, a group receiving both supplements, and a sham-operated group. This well-structured approach allowed us to effectively evaluate the separate and combined impacts of these supplements.
Over a span of 12 weeks, we observed that both curcumin and vitamin D contributed to reduced pain levels on their own. When used together, their analgesic effects were even stronger, providing better pain relief for the rats. Beyond pain relief, supplemental curcumin and vitamin D also showed promising results when we examined inflammatory markers in their serum. We found a decrease in markers of inflammation while levels of the anti-inflammatory cytokine interleukin-10 (IL-10) increased.
Furthermore, we noted improvements in antioxidant levels as well as a significant reduction in the oxidative stress marker known as Cartilage Oligomeric Matrix Protein (COMP). Histological analysis revealed that these supplements helped preserve joint structure and maintain cartilage integrity, while also reducing inflammation in the synovium.
Our findings emphasize the potential of curcumin and vitamin D as effective natural agents in managing knee OA and associated pain. These results could suggest a way to delay the progression of knee OA and improve patient care.
Over a span of 12 weeks, we observed that both curcumin and vitamin D contributed to reduced pain levels on their own. When used together, their analgesic effects were even stronger, providing better pain relief for the rats. Beyond pain relief, supplemental curcumin and vitamin D also showed promising results when we examined inflammatory markers in their serum. We found a decrease in markers of inflammation while levels of the anti-inflammatory cytokine interleukin-10 (IL-10) increased.
Furthermore, we noted improvements in antioxidant levels as well as a significant reduction in the oxidative stress marker known as Cartilage Oligomeric Matrix Protein (COMP). Histological analysis revealed that these supplements helped preserve joint structure and maintain cartilage integrity, while also reducing inflammation in the synovium.
Our findings emphasize the potential of curcumin and vitamin D as effective natural agents in managing knee OA and associated pain. These results could suggest a way to delay the progression of knee OA and improve patient care.
9
Topical curcumin gel effectiveness
We conducted a study to explore the effectiveness of a unique topical gel infused with curcumin, a key ingredient in turmeric, for treating knee osteoarthritis. This innovative gel utilizes a self-nano-emulsifying organogel system, which allows for better delivery of curcumin, a compound known for its challenging solubility and stability issues.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
In our research, we utilized a double-blind clinical trial design to assess the outcomes of participants using the gel compared to those receiving a placebo over an eight-week period. The results were promising; those applying the gel experienced significant reductions in pain, stiffness, and physical function difficulties. Specifically, pain scores improved by 71.68% compared to only 7.03% in the placebo group.
Overall, this study highlights the potential of using curcumin in a new topical treatment that addresses knee pain effectively. While the gel specifically utilizes curcumin, it offers an alternative approach that leverages the benefits of turmeric without relying directly on the spice itself.
8
We explored the effectiveness and safety of curcumin, a compound derived from turmeric, for treating knee osteoarthritis (KOA). Our research involved a comprehensive review of randomized controlled trials to assess how curcumin, whether alone or combined with other treatments, impacts knee pain.
The analysis indicated that curcumin has promising therapeutic potential for KOA, showing good clinical efficacy and a favorable safety profile. It's noteworthy that when curcumin is used in combination with other medications, it may not only enhance the treatment's effect but could also help in reducing side effects.
However, the combined use of treatments means we still await definitive conclusions about curcumin's isolated effects. There's a call for further clinical and basic research to uncover more about this promising approach.
The analysis indicated that curcumin has promising therapeutic potential for KOA, showing good clinical efficacy and a favorable safety profile. It's noteworthy that when curcumin is used in combination with other medications, it may not only enhance the treatment's effect but could also help in reducing side effects.
However, the combined use of treatments means we still await definitive conclusions about curcumin's isolated effects. There's a call for further clinical and basic research to uncover more about this promising approach.
9
In a well-structured study involving 101 adults suffering from knee osteoarthritis, we explored the effects of curcumin, a compound derived from turmeric, on knee pain. Participants were randomly assigned to receive either 500 mg of a standardized curcumin extract, Curcugen, twice daily, or a placebo for eight weeks, allowing for a clear comparison of its effectiveness.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
Our findings revealed promising results. Curcumin significantly reduced knee pain scores and overall pain ratings compared to the placebo. We also noticed that participants taking curcumin showed greater improvements in various physical tests, like the timed up-and-go and six-minute walk tests, indicating enhanced mobility.
Interestingly, 37% of those on curcumin reduced their pain medications, which highlights the potential for curcumin to provide relief and improve quality of life for those with this condition. While the study didn’t explore longer treatment durations or different dosages, these initial results support curcumin's role as a feasible option for managing osteoarthritis pain in the knee.
9
We set out to discover how curcumin, a compound found in turmeric, affects knee pain in individuals with osteoarthritis. Through an extensive review of randomized controlled trials, our analysis included 17 studies that assessed the impact of various curcumin formulations over time periods ranging from 4 weeks to 8 months.
Many of the studies employed well-regarded assessment tools like the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and visual analog scales (VAS) to evaluate pain and functionality. The results painted a hopeful picture, showing significant improvements in pain levels and overall joint function among those taking curcumin.
Notably, we didn't observe any severe side effects linked to curcumin intake, suggesting it could be a safe alternative or complementary option for managing osteoarthritis symptoms. It's worth noting that curcumin compounds with higher bioavailability tended to yield even better results.
Overall, it seems curcumin could be beneficial for those suffering from knee pain due to osteoarthritis, and the findings encourage further exploration into its application in treatment plans.
Many of the studies employed well-regarded assessment tools like the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and visual analog scales (VAS) to evaluate pain and functionality. The results painted a hopeful picture, showing significant improvements in pain levels and overall joint function among those taking curcumin.
Notably, we didn't observe any severe side effects linked to curcumin intake, suggesting it could be a safe alternative or complementary option for managing osteoarthritis symptoms. It's worth noting that curcumin compounds with higher bioavailability tended to yield even better results.
Overall, it seems curcumin could be beneficial for those suffering from knee pain due to osteoarthritis, and the findings encourage further exploration into its application in treatment plans.
References
- Mende LK, Kuthati Y, Wong CS. Curcumin and Vitamin D Supplement Attenuates Knee Osteoarthritis Progression in ACLT + MMx Rat Model: Effect on Cartilage Protection and Pain Reduction. Nutrients. 2025;17. doi:10.3390/nu17020349
- Hidayat R, Parlindungan F, Nisa JI, Mahendra AI, Indika MI, et al. Efficacy of in relieving pain symptoms of knee osteoarthritis patients: a systematic review and meta-analysis of clinical trials. J Rheum Dis. 2025;32:17. doi:10.4078/jrd.2024.0062
- Baharizade M, Ghetmiri SI, Mohammady M, Mohammadi-Samani S, Yousefi G. Revolutionizing Knee Osteoarthritis Treatment: Innovative Self-Nano-Emulsifying Polyethylene Glycol Organogel of Curcumin for Effective Topical Delivery. AAPS PharmSciTech. 2024;25:80. doi:10.1208/s12249-024-02789-8
- Bideshki MV, Jourabchi-Ghadim N, Radkhah N, Behzadi M, Asemani S, et al. The efficacy of curcumin in relieving osteoarthritis: A meta-analysis of meta-analyses. Phytother Res. 2024;38:2875. doi:10.1002/ptr.8153
- Zhao J, Liang G, Zhou G, Hong K, Yang W, et al. Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis. J Ethnopharmacol. 2024;321:117493. doi:10.1016/j.jep.2023.117493
- Valsamidou E, Amerikanou C, Tzavara C, Skarpas G, Mariolis-Sapsakos TD, et al. A standardized nutraceutical supplement contributes to pain relief, improves quality of life and regulates inflammation in knee osteoarthritis patients; A randomized clinical trial. Heliyon. 2023;9:e20143. doi:10.1016/j.heliyon.2023.e20143
- Saber MM, Mahmoud MM, Amin HM, Essam RM. Therapeutic effects of combining curcumin and swimming in osteoarthritis using a rat model. Biomed Pharmacother. 2023;166:115309. doi:10.1016/j.biopha.2023.115309
- Kamat YD, Das B, Thakkar K, Mahajan M. A Retrospective Observational Study Evaluating the Synergistic Effect of a Novel Combination of Alfapin + Native Type 2 Collagen + Mobilee (Hyaluronic Acid) + CurQlife (Curcumin) Nutraceuticals in the Symptomatic Improvement of Knee Osteoarthritis. Cureus. 2023;15:e36123. doi:10.7759/cureus.36123
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