We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
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Most Useful Reviews
9
Pain relief achieved
19 people found this helpful
After giving birth, I experienced aching in my joints and pelvic bone. After taking these vitamins for 1.5 months, I realised the pain had vanished! I wish I had ordered them sooner. I take three tablets daily.
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9
Joint pain reduction
11 people found this helpful
Initially, I struggled with joint pain, but after using this, the pain disappeared, thank God. It contains vitamin D, which has been beneficial. However, it is rather expensive.
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9
Osteoporosis prevention
8 people found this helpful
The effect has been good and the absorption is excellent. My mother, who has been on hormones, was advised by her doctor about the risk of osteoporosis. She tested her bone mineral density and calcium levels, and they're now perfect. We will continue to buy this product.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
User Reviews
USERS' SCORE
Good
Based on 28 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Pain relief achieved
19 people found this helpful
After giving birth, I experienced aching in my joints and pelvic bone. After taking these vitamins for 1.5 months, I realised the pain had vanished! I wish I had ordered them sooner. I take three tablets daily.
Read More
9
Joint pain reduction
11 people found this helpful
Initially, I struggled with joint pain, but after using this, the pain disappeared, thank God. It contains vitamin D, which has been beneficial. However, it is rather expensive.
Read More
9
Osteoporosis prevention
8 people found this helpful
The effect has been good and the absorption is excellent. My mother, who has been on hormones, was advised by her doctor about the risk of osteoporosis. She tested her bone mineral density and calcium levels, and they're now perfect. We will continue to buy this product.
Read More
9
Symptom relief noted
8 people found this helpful
During my second trimester, I experienced aching pains in my teeth and legs. After I ordered this calcium, the symptoms, which had been troubling me, vanished within 1.5 weeks. This indicates to me how effectively these tablets work.
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10
Knee pain healing
5 people found this helpful
This product healed my injured knee in just a week! I had previously taken another brand with insufficient ingredients. After switching to this one, I noticed complete healing of my knee and could climb stairs again. I am very grateful that Iherb sells this.
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Calcium is a chemical element represented by the symbol Ca and atomic number 20. It is an essential mineral in the body, playing a critical role in various physiological processes. As one of the most abundant elements in nature, calcium is particularly vital for maintaining strong bones and teeth, where about 99% of the body's calcium is stored. Beyond its structural function, calcium is crucial in muscle contraction, blood clotting, and nerve transmission, making it a key player in overall health.
Dietary sources of calcium include dairy products such as milk, yogurt, and cheese, as well as leafy green vegetables, nuts, seeds, and fortified foods. The recommended daily intake of calcium varies by age and sex, but generally, adults should aim for approximately 1,000 mg per day. For those who may struggle to meet their needs through diet alone, calcium supplements are available but should be taken with caution. It's essential to consult with a healthcare provider before starting any supplement regimen to avoid potential side effects or interactions with medications.
Calcium is an essential mineral that plays a critical role in maintaining bone health and strength. Adequate calcium intake is crucial for the prevention of various bone-related issues, including osteopenia and osteoporosis, conditions that can lead to increased bone pain and fractures. When the body does not receive enough calcium, it may start to leach this mineral from the bones, potentially leading to weakness and pain. Therefore, ensuring you meet your daily calcium requirements can contribute to healthier bones and may, in turn, help alleviate some types of bone pain associated with deficiencies.
However, it's essential to note that while calcium is fundamental for bone health, it may not directly relieve bone pain caused by other factors such as injury, arthritis, or other medical conditions. For those experiencing chronic bone pain, incorporating calcium-rich foods into your diet—such as dairy products, leafy greens, and fortified foods—should be part of a broader approach that includes medical evaluation and potential treatment options. Consulting a healthcare professional is advised to determine the underlying causes of bone pain and to develop a comprehensive plan that may include dietary adjustments, exercise, and medications if necessary.
Based on user reviews, the time it takes to see results from this bone supplement can vary significantly between individuals. Some users report improvements in conditions like joint and bone pain within a week. For instance, one reviewer mentioned a substantial reduction in back pain after using the supplement for only a week, highlighting its effectiveness in providing quick relief Read Review. Others have experienced noticeable benefits within a month, with one user stating significant improvements to their bone health after four weeks Read Review.
Longer-term users report sustained benefits, with some indicating that consistent use over several months leads to more pronounced results. For example, a user who took the supplement for six months noted their bones felt stronger during that period Read Review. Overall, while some may feel immediate effects, others might require more time to fully experience the benefits of this supplement for bone pain.
This supplement is potentially related to bone pain management, particularly calcium, based on findings from a study that examined patients experiencing bone pain due to osteomalacia linked to intravenous iron infusions. In this research, 13 patients received supportive treatment that included calcium, phosphate, and active Vitamin D, leading to improvements in biochemical markers and reduced pain scores [1]. However, it is essential to note that the study could not specifically isolate the effects of calcium on bone pain from other treatments administered concurrently.
While the study indicates some positive outcomes associated with calcium supplementation, the direct correlation between calcium intake and alleviation of bone pain remains ambiguous, primarily due to the multifaceted nature of the treatment approach. Therefore, while there is some supporting evidence regarding the benefits of supportive treatments in improving bone health and reducing pain, the definitive impact of calcium alone on bone pain is still unclear.
Based on user reviews, many individuals have reported significant improvements in their symptoms after using this calcium supplement. For instance, one user noted that after just 1.5 months of use, their joint and pelvic bone pain had completely vanished following childbirth Read Review. Another reviewer shared a similar experience, stating that their joint pain disappeared after starting the supplement, attributing the relief to the beneficial effects of vitamin D included in the formula Read Review. Users also mentioned impressive results in terms of bone health; one user reported not just relief, but a noticeable improvement in their bone density after three months of consistent use Read Review.
Additionally, several users highlighted quick positive responses, such as alleviating aching pains within just a week of starting the supplement Read Review. Pregnant and breastfeeding women noted benefits as well, reporting fewer spasms and improved tooth sensitivity Read Review. Overall, while individual results can certainly vary, many users have found that this calcium supplement not only helps with pain relief but promotes overall bone strength.
Users have reported positive experiences when combining this supplement with other vitamins and minerals, particularly vitamin D, to enhance its effectiveness. One user noted that after being advised to take calcium with vitamin D3, they significantly improved their bone health, indicating a synergistic effect between the two nutrients Read Review. Another reviewer echoed this sentiment, stating that the inclusion of vitamin D was beneficial in alleviating joint pain Read Review.
Some individuals also mentioned potential imbalances in the calcium-to-magnesium ratio, suggesting that additional magnesium supplementation may be necessary to optimize overall benefits Read Review. Overall, combining this calcium supplement with other nutrients, especially vitamin D, appears to be a common and effective approach among users for managing bone pain and enhancing bone health.
Users report varying doses for calcium supplementation when addressing bone pain. Many find success with higher doses, such as three tablets daily, which some users like to take to effectively manage their pain. For instance, one user noted significant relief from joint and pelvic pain after consistently taking three tablets daily for 1.5 months (Read Review). Another user experienced remarkable results during pregnancy with only half a pack taken, contributing to reduced leg pain and discomfort (Read Review).
Several reviews emphasize the importance of combining calcium with vitamin D3 to enhance absorption and effectiveness (Read Review). Users advocate for products that contain complementary ingredients that support bone health, which could influence their perceived effectiveness and dosage recommendations. Ultimately, while user experiences suggest positive outcomes with varying doses of calcium, the ideal amount can depend on individual health needs, age, and lifestyle factors.
7.5
Back pain relief
3 people found this helpful
I've taken this for a week and already feel an improvement in my bones. My previous back pain has lessened significantly. It’s truly effective, and I will be ordering it again.
7.5
Bone improvement observed
4 people found this helpful
This product is wonderful. After using it for a month, I've noticed a significant improvement in my bones. I am quite pleased with the results.
9
Stronger bones felt
3 people found this helpful
I've been taking these vegan tablets for six months, and I can feel my bones getting stronger. They don’t cause any side effects, and my stomach feels great when I take them. I'm very satisfied!
9
Pain relief achieved
19 people found this helpful
After giving birth, I experienced aching in my joints and pelvic bone. After taking these vitamins for 1.5 months, I realised the pain had vanished! I wish I had ordered them sooner. I take three tablets daily.
9
Joint pain reduction
11 people found this helpful
Initially, I struggled with joint pain, but after using this, the pain disappeared, thank God. It contains vitamin D, which has been beneficial. However, it is rather expensive.
7.5
Successful recovery
1 people found this helpful
I bought this for my mother after she had augmented bone tissue prior to getting implants. Following the calcium course advised by her doctor, her bone tissue engrafted perfectly on the X-ray three months later. No side effects were observed.
9
Symptom relief noted
8 people found this helpful
During my second trimester, I experienced aching pains in my teeth and legs. After I ordered this calcium, the symptoms, which had been troubling me, vanished within 1.5 weeks. This indicates to me how effectively these tablets work.
9
Improved bone health
3 people found this helpful
I was advised by a nutritionist to take calcium with vitamin D3, as they enhance each other's effectiveness. I also give it to my mother, who had a deficiency in ionised calcium. It significantly aids in the health of bones, the entire body, and teeth. I love this herbal product!
6
Imbalanced magnesium
15 people found this helpful
This supplement not only contains calcium but also additional plant-derived elements for bone health. However, the calcium:magnesium ratio is imbalanced, as it has only 60mg of magnesium compared to 800mg of calcium, which may necessitate an extra magnesium supplement.
9
Pain relief noted
My mother only consumed half a pack, yet she experienced a reduction in her leg pain and the crunching sensation has vanished.
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
References
von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139