' 
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 3 Tablets
Serving Per Container: 30
Amount Per Serving
%DV
Vitamin D*
25 mcg (1,000 IU)
125%
Calcium (from Organic Algae)
800 mg
62%
Magnesium (from Organic Algae)
60 mg
14%
Vitamin K2 (as menaquinone-7 from Natto)
80 mcg
+
Strontium (from Organic Algae)
4 mg
+
Vanadium (from Organic Algae)
8 mcg
+
Organic Plant Calcium Blend Organic algae, organic apple (fruit), organic beet (root), organic broccoli (stalk & flower), organic carrot (root), organic spinach (leaf), organic tomato (fruit), organic strawberry (fruit), organic cherry (fruit), organic blackberry (fruit), organic green bell pepper (fruit), organic brussels sprout (leaf), organic ginger (root), organic blueberry (fruit), organic garlic (bulb), organic green onion (bulb), organic raspberry (fruit), organic parsley (leaf), organic cauliflower (flower & stem), organic red cabbage (leaf), organic kale (leaf), organic cucumber (gourd), organic celery (stalk), organic asparagus (flower & stem).
3.3 g
+
Top Medical Research Studies
7
Calcium's role in stenting assessed
A Revised Optical Coherence Tomography-Derived Calcium Score to Predict Stent Underexpansion in Severely Calcified Lesions.
Limited impact on heart disease
We explored how severe calcium buildup in arteries may affect the success of heart stenting procedures, specifically focusing on identifying which calcified lesions might risk underexpansion of stents. In a study of 250 cases where optical coherence tomography (OCT) helped guide stenting, only those not treated with specific preparation methods were included.
The key findings showed that a significant portion—about 20%—of the lesions displayed stent underexpansion. We also discovered that certain features of the calcium, such as an angle over 270 degrees and a substantial thickness, were connected to reduced stent expansion.
Although the study emphasized calcium's role in predicting stent outcomes, we noted that it didn’t isolate how calcium management impacts heart disease directly. Thus, while the revised calcium scoring system can be useful in assessing stent expansion risk, the benefits of calcium treatment on heart disease remain less clear.
The key findings showed that a significant portion—about 20%—of the lesions displayed stent underexpansion. We also discovered that certain features of the calcium, such as an angle over 270 degrees and a substantial thickness, were connected to reduced stent expansion.
Although the study emphasized calcium's role in predicting stent outcomes, we noted that it didn’t isolate how calcium management impacts heart disease directly. Thus, while the revised calcium scoring system can be useful in assessing stent expansion risk, the benefits of calcium treatment on heart disease remain less clear.
Read More
9
Mitochondrial calcium uptake and heart
Enhancement of mitochondrial calcium uptake is cardioprotective against maladaptive hypertrophy by retrograde signaling uptuning Akt.
MCU's role in heart health
We explored how enhancing mitochondrial calcium uptake can influence heart disease, particularly in the context of heart hypertrophy, a condition that can lead to heart failure. The study focused on the mitochondrial calcium uniporter (MCU), a protein responsible for transporting calcium into mitochondria.
By examining heart samples from humans and mice at different stages of hypertrophy, we found that MCU levels increased during the initial adaptive phase but decreased when heart failure occurred. This tells us that the body tries to cope with added stress before ultimately struggling.
Our experiments involved manipulating MCU levels in mice through viral techniques, allowing us to observe the effects during pressure overload, simulating conditions of heart disease. We noticed that reducing MCU led to faster deterioration of heart function and increased fibrosis, indicating a poorer health status. Conversely, boosting MCU seemed to help preserve heart function and maintain tissue health even under stress.
Importantly, we found that improved mitochondrial calcium uptake triggered protective signals involving reactive oxygen species and Akt activation within the heart cells. These findings suggest that enhancing calcium uptake could offer a potential therapeutic strategy against maladaptive heart hypertrophy and contribute to a healthier heart response under stress.
By examining heart samples from humans and mice at different stages of hypertrophy, we found that MCU levels increased during the initial adaptive phase but decreased when heart failure occurred. This tells us that the body tries to cope with added stress before ultimately struggling.
Our experiments involved manipulating MCU levels in mice through viral techniques, allowing us to observe the effects during pressure overload, simulating conditions of heart disease. We noticed that reducing MCU led to faster deterioration of heart function and increased fibrosis, indicating a poorer health status. Conversely, boosting MCU seemed to help preserve heart function and maintain tissue health even under stress.
Importantly, we found that improved mitochondrial calcium uptake triggered protective signals involving reactive oxygen species and Akt activation within the heart cells. These findings suggest that enhancing calcium uptake could offer a potential therapeutic strategy against maladaptive heart hypertrophy and contribute to a healthier heart response under stress.
Read More
8
Calcium scoring aids heart disease prevention
Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease: A Randomized Clinical Trial.
Moderate relevance to calcium treatment
We conducted a randomized trial to see how combining coronary artery calcium (CAC) scoring with a prevention strategy could limit plaque progression in patients who have a family history of heart disease. The study involved participants aged 40 to 70 who were asymptomatic but had relatives with early-onset coronary artery disease (CAD).
For those who had a CAC score between 1 and 399, we randomized them into two groups: one followed a prevention plan informed by their CAC score, while the other received usual care. After three years, we measured the plaque volume through follow-up assessments to observe how each group fared in terms of plaque progression.
Remarkably, our findings indicated that using the CAC score alongside a primary prevention approach helped reduce harmful lipids in the blood and slowed the development of plaque compared to standard care. This suggests that the CAC score can play a vital role in informing and enhancing preventive measures for those at intermediate risk of heart disease.
For those who had a CAC score between 1 and 399, we randomized them into two groups: one followed a prevention plan informed by their CAC score, while the other received usual care. After three years, we measured the plaque volume through follow-up assessments to observe how each group fared in terms of plaque progression.
Remarkably, our findings indicated that using the CAC score alongside a primary prevention approach helped reduce harmful lipids in the blood and slowed the development of plaque compared to standard care. This suggests that the CAC score can play a vital role in informing and enhancing preventive measures for those at intermediate risk of heart disease.
Read More
Most Useful Reviews
9.5
Recommended product
It’s truly a great brand. I began to replenish calcium after three months of pregnancy and found the ingredients very reassuring. Although taking it three times a day is a bit tedious, I believe it aids absorption. I’ve noticed improvements and haven’t experienced constipation, unlike with other synthetic calcium products, which has been a relief. This is definitely a product I would recommend.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
- All Researches
9
Mitochondrial calcium uptake and heart
Enhancement of mitochondrial calcium uptake is cardioprotective against maladaptive hypertrophy by retrograde signaling uptuning Akt.
MCU's role in heart health
We explored how enhancing mitochondrial calcium uptake can influence heart disease, particularly in the context of heart hypertrophy, a condition that can lead to heart failure. The study focused on the mitochondrial calcium uniporter (MCU), a protein responsible for transporting calcium into mitochondria.
By examining heart samples from humans and mice at different stages of hypertrophy, we found that MCU levels increased during the initial adaptive phase but decreased when heart failure occurred. This tells us that the body tries to cope with added stress before ultimately struggling.
Our experiments involved manipulating MCU levels in mice through viral techniques, allowing us to observe the effects during pressure overload, simulating conditions of heart disease. We noticed that reducing MCU led to faster deterioration of heart function and increased fibrosis, indicating a poorer health status. Conversely, boosting MCU seemed to help preserve heart function and maintain tissue health even under stress.
Importantly, we found that improved mitochondrial calcium uptake triggered protective signals involving reactive oxygen species and Akt activation within the heart cells. These findings suggest that enhancing calcium uptake could offer a potential therapeutic strategy against maladaptive heart hypertrophy and contribute to a healthier heart response under stress.
By examining heart samples from humans and mice at different stages of hypertrophy, we found that MCU levels increased during the initial adaptive phase but decreased when heart failure occurred. This tells us that the body tries to cope with added stress before ultimately struggling.
Our experiments involved manipulating MCU levels in mice through viral techniques, allowing us to observe the effects during pressure overload, simulating conditions of heart disease. We noticed that reducing MCU led to faster deterioration of heart function and increased fibrosis, indicating a poorer health status. Conversely, boosting MCU seemed to help preserve heart function and maintain tissue health even under stress.
Importantly, we found that improved mitochondrial calcium uptake triggered protective signals involving reactive oxygen species and Akt activation within the heart cells. These findings suggest that enhancing calcium uptake could offer a potential therapeutic strategy against maladaptive heart hypertrophy and contribute to a healthier heart response under stress.
Read More
8
Calcium scoring aids heart disease prevention
Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease: A Randomized Clinical Trial.
Moderate relevance to calcium treatment
We conducted a randomized trial to see how combining coronary artery calcium (CAC) scoring with a prevention strategy could limit plaque progression in patients who have a family history of heart disease. The study involved participants aged 40 to 70 who were asymptomatic but had relatives with early-onset coronary artery disease (CAD).
For those who had a CAC score between 1 and 399, we randomized them into two groups: one followed a prevention plan informed by their CAC score, while the other received usual care. After three years, we measured the plaque volume through follow-up assessments to observe how each group fared in terms of plaque progression.
Remarkably, our findings indicated that using the CAC score alongside a primary prevention approach helped reduce harmful lipids in the blood and slowed the development of plaque compared to standard care. This suggests that the CAC score can play a vital role in informing and enhancing preventive measures for those at intermediate risk of heart disease.
For those who had a CAC score between 1 and 399, we randomized them into two groups: one followed a prevention plan informed by their CAC score, while the other received usual care. After three years, we measured the plaque volume through follow-up assessments to observe how each group fared in terms of plaque progression.
Remarkably, our findings indicated that using the CAC score alongside a primary prevention approach helped reduce harmful lipids in the blood and slowed the development of plaque compared to standard care. This suggests that the CAC score can play a vital role in informing and enhancing preventive measures for those at intermediate risk of heart disease.
Read More
7
Calcium's role in stenting assessed
A Revised Optical Coherence Tomography-Derived Calcium Score to Predict Stent Underexpansion in Severely Calcified Lesions.
Limited impact on heart disease
We explored how severe calcium buildup in arteries may affect the success of heart stenting procedures, specifically focusing on identifying which calcified lesions might risk underexpansion of stents. In a study of 250 cases where optical coherence tomography (OCT) helped guide stenting, only those not treated with specific preparation methods were included.
The key findings showed that a significant portion—about 20%—of the lesions displayed stent underexpansion. We also discovered that certain features of the calcium, such as an angle over 270 degrees and a substantial thickness, were connected to reduced stent expansion.
Although the study emphasized calcium's role in predicting stent outcomes, we noted that it didn’t isolate how calcium management impacts heart disease directly. Thus, while the revised calcium scoring system can be useful in assessing stent expansion risk, the benefits of calcium treatment on heart disease remain less clear.
The key findings showed that a significant portion—about 20%—of the lesions displayed stent underexpansion. We also discovered that certain features of the calcium, such as an angle over 270 degrees and a substantial thickness, were connected to reduced stent expansion.
Although the study emphasized calcium's role in predicting stent outcomes, we noted that it didn’t isolate how calcium management impacts heart disease directly. Thus, while the revised calcium scoring system can be useful in assessing stent expansion risk, the benefits of calcium treatment on heart disease remain less clear.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Recommended product
It’s truly a great brand. I began to replenish calcium after three months of pregnancy and found the ingredients very reassuring. Although taking it three times a day is a bit tedious, I believe it aids absorption. I’ve noticed improvements and haven’t experienced constipation, unlike with other synthetic calcium products, which has been a relief. This is definitely a product I would recommend.
Read More
