Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container:  30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+

Top Medical Research Studies

8
Magnesium improves chest pain outcomes
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
8
Magnesium shows promise for angina
We aimed to understand how a 24-hour infusion of magnesium sulphate affects patients with unstable angina. In a double-blind, placebo-controlled study, 62 patients were monitored for signs of myocardial ischaemia after receiving either magnesium or a placebo.

While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.

Most Useful Reviews

9
Eliminated back pain
14 people found this helpful
Raw Calcium has completely alleviated my low back ache during my monthly cycle, something I did not expect. My calcium levels have been low in the past, and other supplements, including calcium citrate, often lead to chest pain. Thankfully, I do not experience this with GOL's raw calcium. Initially hesitant, I’m now grateful I tried it; the absence of back pain makes me nearly forget about my cycle.
9
Headache relief
1 people found this helpful
My headaches and chest tightness have vanished, leaving me feeling revitalised.
9
Pain relief
Osteoporosis pain has disappeared within three days of taking this fantastic product. I truly love it!

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.5
  • All Researches
We looked at the case of a 69-year-old woman experiencing intermittent shortness of breath and chest pain. Interestingly, she also described a peculiar symptom—a phantom odor sensation that preceded her episodes. During an exercise stress echocardiography, she demonstrated abnormal smell perception alongside transient changes in her heart's electrical activity, which indicated possible cardiac issues.

After conducting invasive coronary angiography, no significant blockages were found in her coronary arteries. This led to a diagnosis of vasospastic angina, a condition that can cause chest pain due to spasms in the coronary arteries rather than physical blockages. To alleviate her symptoms, she was started on calcium channel blocker therapy. Thankfully, this treatment helped in resolving her discomfort.

While the study highlights the role of calcium treatment in managing her symptoms effectively, it's essential to note that this isn't a guaranteed solution for everyone with chest pain. Phantom odors as an indicative symptom of cardiovascular issues are quite rare, suggesting a need for healthcare providers to remain vigilant when patients present with atypical symptoms.
9.5
Calcium channels alleviate chest pain
We explored the unusual case of a 50-year-old premenopausal woman suffering from vasospastic angina (VSA), a form of chest pain resulting from coronary artery spasms. Our patient's daily chest pain, triggered by light exertion, led to testing that revealed mild-to-moderate isolated coronary ostial stenosis (ICOS) along with multi-vessel spasms.

Interestingly, despite the severity often associated with ICOS, she experienced considerable relief after starting treatment with calcium channel blockers (CCBs). This finding is significant as it shows how CCB therapy can effectively manage VSA symptoms, leading to alleviation of chest pain without the need for surgical intervention for ICOS—even over a stretch of 24 years.

Notably, follow-up imaging after this duration indicated that ICOS had resolved, suggesting a remarkable possibility of improvement. However, we should remember that while the use of CCBs proved beneficial in this instance, the results highlight the ongoing need for research into the efficacy of different treatments for chest pain.
9.5
Magnesium's unclear role in chest pain
We examined the role of magnesium in treating chest pain, particularly in a case involving a young female with Gitelman syndrome. This patient experienced recurrent chest pain alongside symptoms like tingling and numbness, prompting a thorough investigation into her condition.

Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.

While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
9
Calcium treatment aids chest pain
We explored how calcium channel blockers (CCBs) can help patients with chest pain, particularly in those who also have heart failure with reduced ejection fraction (HFrEF) and myocardial infarction with non-obstructive coronary arteries (MINOCA).

An 83-year-old woman was admitted with significant shortness of breath and a notable decline in her heart's pumping ability, also accompanied by intermittent chest pain. Although initial tests showed no major blockages in her coronary arteries, a more precise method revealed that she was experiencing severe coronary spasms.

After starting her on dihydropyridine CCBs, we observed a remarkable improvement. Her chest pain gradually went away, and her heart function improved dramatically, as indicated by her higher ejection fraction and lower levels of heart stress markers.

This suggests that CCBs, although not commonly prescribed for HFrEF, can have a useful role in managing chest pain and improving heart function in specific cases. Therefore, we found that tailored treatments and comprehensive diagnostic approaches can lead to better outcomes for patients with similar conditions.
We investigated the effectiveness of vitamin D in relieving chest pain associated with a complex case of adult-onset hypophosphatemic osteomalacia (HO) in a 47-year-old woman suffering from Sjogren’s syndrome. In this case, the patient experienced progressively worsening pain in the chest, back, and legs, along with muscle weakness, raising questions about the underlying causes and appropriate treatment options.

After examining lab results, radiographic findings, and pathology, the diagnosis of adult-onset HO was confirmed. The treatment regimen included not only vitamin D but also alkalinization, steroids, neutral phosphate, and calcium supplements. Although the combination of treatments resulted in improved outcomes—such as pain relief and increased serum phosphorus levels—it’s difficult to isolate the effect of vitamin D specifically on chest pain, as it was one part of a broader therapeutic approach.

This case highlights the challenges of diagnosing and treating complex conditions like hypophosphatemic osteomalacia, particularly when associated with autoimmune disorders like Sjogren's syndrome. It underscores the importance of considering various factors and the potential interplay of treatments in managing such cases.

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Eliminated back pain
14 people found this helpful
Raw Calcium has completely alleviated my low back ache during my monthly cycle, something I did not expect. My calcium levels have been low in the past, and other supplements, including calcium citrate, often lead to chest pain. Thankfully, I do not experience this with GOL's raw calcium. Initially hesitant, I’m now grateful I tried it; the absence of back pain makes me nearly forget about my cycle.
9
Headache relief
1 people found this helpful
My headaches and chest tightness have vanished, leaving me feeling revitalised.
9
Pain relief
Osteoporosis pain has disappeared within three days of taking this fantastic product. I truly love it!
0
Condition improvement
1 people found this helpful
I've been dealing with gastritis, and it's been a painful experience regarding my heart.

Frequently Asked Questions

9
Headache relief
1 people found this helpful
My headaches and chest tightness have vanished, leaving me feeling revitalised.
9
Pain relief
Osteoporosis pain has disappeared within three days of taking this fantastic product. I truly love it!
9
Eliminated back pain
14 people found this helpful
Raw Calcium has completely alleviated my low back ache during my monthly cycle, something I did not expect. My calcium levels have been low in the past, and other supplements, including calcium citrate, often lead to chest pain. Thankfully, I do not experience this with GOL's raw calcium. Initially hesitant, I’m now grateful I tried it; the absence of back pain makes me nearly forget about my cycle.
0
Condition improvement
1 people found this helpful
I've been dealing with gastritis, and it's been a painful experience regarding my heart.
We explored the relationship between calcium channel blockers (CCBs) and chest pain in the context of a case involving paroxysmal atrial fibrillation (AF) caused by coronary artery spasm. The patient, a male with a smoking history but no significant risk factors, initially presented with palpitations diagnosed as AF.

Over the course of a year, he experienced recurring episodes of chest pain that coincided with his AF. Upon conducting a coronary angiography, doctors found normal coronary anatomy, but a provocation test confirmed the presence of coronary spasm leading to arrhythmia.

Following this diagnosis, the use of CCBs like nifedipine, alongside isosorbide mononitrate, effectively prevented the recurring episodes of chest pain and AF. This suggests that calcium treatment can play a beneficial role in managing chest pain associated with coronary spasms, especially when used in combination with other medications.
9
Calcium treatment aids chest pain
We explored how calcium channel blockers (CCBs) can help patients with chest pain, particularly in those who also have heart failure with reduced ejection fraction (HFrEF) and myocardial infarction with non-obstructive coronary arteries (MINOCA).

An 83-year-old woman was admitted with significant shortness of breath and a notable decline in her heart's pumping ability, also accompanied by intermittent chest pain. Although initial tests showed no major blockages in her coronary arteries, a more precise method revealed that she was experiencing severe coronary spasms.

After starting her on dihydropyridine CCBs, we observed a remarkable improvement. Her chest pain gradually went away, and her heart function improved dramatically, as indicated by her higher ejection fraction and lower levels of heart stress markers.

This suggests that CCBs, although not commonly prescribed for HFrEF, can have a useful role in managing chest pain and improving heart function in specific cases. Therefore, we found that tailored treatments and comprehensive diagnostic approaches can lead to better outcomes for patients with similar conditions.
8
Vitamin D deficiency affects symptoms
We aimed to understand how vitamin D deficiency (VDD) might influence symptoms like chest pain, anxiety, and fatigue in people living with coronary artery disease (CAD). In our investigation, we collected data from 90 CAD patients, focusing on their vitamin D levels and experiences with these symptoms.

The findings were quite revealing. A significant 80% of the participants were found to have low vitamin D levels. Interestingly, we discovered that lower vitamin D levels were linked to increased chest pain and heightened anxiety and fatigue. Specifically, there were strong negative relationships noted: as vitamin D levels dropped, chest pain, anxiety, and fatigue scores rose.

This suggests that addressing vitamin D deficiency might be an important step for managing cardiac-related symptoms in patients with CAD. As this connection unfolds, it seems valuable for healthcare providers to monitor vitamin D levels in CAD patients and consider interventions to correct deficiencies.
We investigated how vitamin D influences chest pain in individuals experiencing vaccine-related myocarditis after receiving the BNT162b2 COVID-19 vaccine. Our study involved analyzing vitamin D levels, immune profiles, and genetic factors in 60 patients who suffered from this condition.

A significant finding was that a high percentage of these patients, about 73.3%, were found to have low vitamin D levels. Particularly concerning was the observation that those patients who presented with chest pain were more likely to be vitamin D deficient. We also found that lower vitamin D levels were linked to higher peak levels of cardiac troponin T, a marker indicating heart stress.

Additionally, we explored genetic factors and found that certain genetic variations could either increase or increase the potential risk related to vitamin D status. These findings suggest that hypovitaminosis D may exacerbate inflammation and activate specific immune cells, leading to symptoms like chest pain.

Overall, our research supports the idea that improving vitamin D status could be crucial in reducing vaccine-related myocarditis and associated chest pain, revealing a path for potential preventive measures and treatment strategies.

References

  1. El Sady BD, Shaker AM, Abdulsaboor A, Ahmed A, Salama ABM. Paroxysmal Atrial Fibrillation as the First Presentation of Coronary Artery Spasm. Cureus. 2024;16:e71186. doi:10.7759/cureus.71186
  2. Ikebe S, Yamamoto M, Ishii M, Yamamoto E, Tsujita K. Managing heart failure with reduced ejection fraction merged with myocardial infarction with non-obstructive coronary arteries: a case report. Eur Heart J Case Rep. 2024;8:ytae540. doi:10.1093/ehjcr/ytae540
  3. Zubair H, Suma V, Masood F, Jan MF, Bajwa T, et al. Case Report: Vasospastic angina presenting as phantom odor perception. Front Cardiovasc Med. 2024;11:1416149. doi:10.3389/fcvm.2024.1416149
  4. Takahashi K, Kodama A, Uemura S, Okura T. Bilateral isolated coronary ostial stenosis in a middle-aged premenopausal woman with vasospastic angina: a case report. Eur Heart J Case Rep. 2024;8:ytae249. doi:10.1093/ehjcr/ytae249
  5. Tsang HW, Chua GT, Tung KTS, Wong RSM, Tsao SSL, et al. The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis. Front Immunol. 2025;16:1501609. doi:10.3389/fimmu.2025.1501609
  6. Khater WA, Alfarkh MA, Allnoubani A. The Association Between Vitamin D Level and Chest Pain, Anxiety, and Fatigue in Patients With Coronary Artery Disease. Clin Nurs Res. 2023;32:639. doi:10.1177/10547738221126325
  7. Alkhatatbeh MJ, Abdul-Razzak KK, Amara NA, Al-Jarrah M. Non-cardiac Chest Pain and Anxiety: A Possible Link to Vitamin D and Calcium. J Clin Psychol Med Settings. 2019;26:194. doi:10.1007/s10880-018-9579-2
  8. Tsuchiya M, Takaki R, Kobayashi F, Nagasaka T, Shindo K, et al. [Multiple pseudofractures due to Fanconi's syndrome associated with Wilson's disease]. Rinsho Shinkeigaku. 2017;57:527. doi:10.5692/clinicalneurol.cn-000953
  9. Shen G, Zhang Y, Hu S, Liu B, Kuang A. Adult-onset hypophosphatemic osteomalacia associated with Sjogren syndrome: Clinical case report. Medicine (Baltimore). 2017;96:e6493. doi:10.1097/MD.0000000000006493
  10. Lee J, Fields KB. Sternal stress fracture in a middle-aged woman. BMJ Case Rep. 2017;2017. doi:10.1136/bcr-2016-218203
  11. Ola O, Gharacholou SM, Del-Carpio Munoz F. Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room". JAMA Intern Med. 2021;181:1393. doi:10.1001/jamainternmed.2021.4021
  12. Poudel A. An adolescent with tingling and numbness of hand: gitelman syndrome. N Am J Med Sci. 2015;7:27. doi:10.4103/1947-2714.150086
  13. Amoozgar H, Rafizadeh H, Ajami G, Borzoee M. The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy. Int Cardiovasc Res J. 2012;6:92.
  14. Zhi YF, Huang YS, Xu BS, Wang SR. [Clinical investigation of the protective effects of potassium magnesium aspartate against arrhythmia and its possible anti-oxidative mechanism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:662.
  15. Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, et al. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006;40:773.
  16. Sovová E, Skvarilová M, Bartousek J, Doupal V, Lukl J, et al. [Latent tetany in patients with a negative coronarographic finding]. Vnitr Lek. 1999;45:291.
  17. Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.
  18. Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.
  19. Ezhov AV, Pimenov LT. [Effect of adjuvant magnesium therapy on the quality of life and emotional status of elderly patients with stable angina]. Adv Gerontol. 2002;10:95.
  20. Teragawa H, Kato M, Yamagata T, Matsuura H, Kajiyama G. The preventive effect of magnesium on coronary spasm in patients with vasospastic angina. Chest. 2000;118:1690.
  21. Sueda S, Saeki H, Otani T, Mineoi K, Kondo T, et al. Limited efficacy of magnesium for the treatment of variant angina. J Cardiol. 1999;34:139.
  22. Shibata M, Ueshima K, Harada M, Nakamura M, Hiramori K, et al. Effect of magnesium sulfate pretreatment and significance of matrix metalloproteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infarction. Angiology. 1999;50:573.
  23. Redwood SR, Bashir Y, Huang J, Leatham EW, Kaski JC, et al. Effect of magnesium sulphate in patients with unstable angina. A double blind, randomized, placebo-controlled study. Eur Heart J. 1997;18:1269.
  24. Satake K, Lee JD, Shimizu H, Ueda T, Nakamura T. Relation between severity of magnesium deficiency and frequency of anginal attacks in men with variant angina. J Am Coll Cardiol. 1996;28:897.
  25. Gawaz M, Reininger A, Neumann FJ. Platelet function and platelet-leukocyte adhesion in symptomatic coronary heart disease. Effects of intravenous magnesium. Thromb Res. 1996;83:341.
  26. Otani H, Kawasaki H, Ninomiya H, Kido M, Kawaguchi H. [Significance of hot shot in patients with unstable angina undergoing emergency coronary artery bypass graft surgery]. Nihon Kyobu Geka Gakkai Zasshi. 1996;44:123.
  27. Caspi J, Rudis E, Bar I, Safadi T, Saute M. Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg. 1995;59:942.
  28. Feldstedt M, Boesgaard S, Bouchelouche P, Svenningsen A, Brooks L, et al. Magnesium substitution in acute ischaemic heart syndromes. Eur Heart J. 1991;12:1215.
  29. Tanabe K, Noda K, Mikawa T, Murayama M, Sugai J. Magnesium content of erythrocytes in patients with vasospastic angina. Cardiovasc Drugs Ther. 1991;5:677.
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