'
SCIENTIFIC SCORE
Moderately Effective
Based on 15 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.7
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container:  30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+

Top Medical Research Studies

9
Magnesium aids migraine management
Magnesium and Migraine.
Directly studies magnesium’s effect
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
8
Vitamin D reduces headache risk
New evidence that vitamin D prevents headache: a bidirectional two-sample Mendelian randomization analysis.
Direct effect of vitamin D observed
We explored the potential connection between vitamin D levels and headaches through a thorough investigation using two-sample Mendelian randomization analysis. Our goal was to determine if there’s a causal relationship between high vitamin D levels and the risk of experiencing headaches.

Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.

This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Read More
8
Vitamin D may reduce migraines
The association of serum vitamin D concentrations in paediatric migraine.
High relevance to headache treatment
We aimed to investigate how vitamin D levels might impact migraine occurrences in children. Recent research highlighted that many youngsters experience migraines, and intriguingly, vitamin D has been linked to various neurological conditions.

In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.

While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
Read More

Most Useful Reviews

9.5
Headache relief
The headache and chest tightness vanished, leaving me feeling revitalised.
Read More
9.5
Headache improvement
I’m very pleased with the fast delivery and high-quality product. Although the capsules are slightly large, they are easy to swallow. I've been taking them for 10 days and have noticed fewer headaches and more energy. My mood has also improved significantly. I recommend it for anyone dealing with headaches or interested in fitness.
Read More
8.8
Headache management
It truly helps with headaches and insomnia, but it's important to eat regularly; otherwise, the headache returns quickly.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 15 Researches
8
9.5
Calcium's uncertain headache impact
Reversible Cerebral Vasoconstriction Syndrome Secondary to Escitalopram.
Study raises questions on effectiveness
We explored the connection between calcium treatment and headaches, particularly in patients with reversible cerebral vasoconstriction syndrome (RCVS). In this case, we observed a healthy young woman who had been using escitalopram for a long time. She presented with bilateral neurological deficits, and after treatment with intra-arterial calcium channel blockers, her symptoms improved significantly.

However, it’s important to note that while calcium channel blockers were administered, the study does not specifically isolate calcium’s effects on headache relief. This combination of treatments makes it challenging to understand how much calcium alone contributes to alleviating headache symptoms, if at all.

As we considered the overall findings, it became clear that while calcium channel blockers can lead to symptom improvement in RCVS, the direct impact of calcium on headaches remains uncertain. Therefore, individuals experiencing thunderclap headaches, especially those on selective serotonin reuptake inhibitors, should consider RCVS as a possible diagnosis, but we cannot definitively conclude that calcium treatment is effective for headaches based on this case alone.
Read More
9
Vitamin D helps manage migraines
The Impact of Vitamin D Supplementation to Topiramate Therapy on Pediatric Migraine Prophylaxis.
Significant findings on supplementation
We conducted a clinical trial to investigate the effects of vitamin D supplementation alongside topiramate, a medication commonly used for migraine prevention in children aged 5 to 14. In this double-blind study, participants were divided into two groups: one received vitamin D with their topiramate treatment, while the other received a placebo.

After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.

Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
Read More
9
Magnesium aids migraine management
Magnesium and Migraine.
Directly studies magnesium’s effect
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
9
Magnesium's role in headache treatment
[Therapeutic approaches to comorbid pathology in episodic migraine and tension-type headache].
Combined treatment limits magnesium's isolation
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.

Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.

Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Read More
8
Combined treatment benefits migraines
Effects of probiotic and vitamin D co-supplementation on clinical symptoms, mental health, and inflammation in adult patients with migraine headache: a randomized, triple-blinded, placebo-controlled trial.
Moderate relevance to vitamin D
We conducted a randomized, triple-blinded, placebo-controlled trial focusing on the effects of vitamin D and probiotic co-supplementation on migraine headaches. This study included adult patients aged 18 to 55 diagnosed with migraines, specifically using the International Classification of Headache Disorders-3 criteria.

Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.

Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Headache relief
The headache and chest tightness vanished, leaving me feeling revitalised.
9.5
Headache improvement
I’m very pleased with the fast delivery and high-quality product. Although the capsules are slightly large, they are easy to swallow. I've been taking them for 10 days and have noticed fewer headaches and more energy. My mood has also improved significantly. I recommend it for anyone dealing with headaches or interested in fitness.
Read More
8.8
Headache management
It truly helps with headaches and insomnia, but it's important to eat regularly; otherwise, the headache returns quickly.
8.8
Natural headache relief
The natural ingredients in this calcium supplement are easily absorbed and have relieved my headaches. The packaging is good, and I would recommend it.
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