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Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D (as D3 from culture of Saccharomyces cerevisiae)
125 mcg (5,000 IU)
625%
High Omega-9 Cracked-Wall Chlorella
250 mg
+
RAW Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Green Bell Pepper (fruit), Organic Blackberry (fruit), Organic Brussels Sprout (leaf), Organic Ginger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Blueberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Raspberry (fruit), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
150 mg
+
RAW Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU)
60 mg
+
The product is found useful for the following medical conditions
Bone Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 13 Reviews
8.6
9
Vitamin D3 correction improves pain
Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty.
Most Relevant Research
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.
By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.
Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.
Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
9.5
Life-changing experience
Most Useful Review
I absolutely love this supplement! Vitamin D has transformed my life. I visited the doctor due to severe bone pain, thinking it might be arthritis. I was taken aback to find out I was extremely deficient in vitamin D. Since commencing this supplement, I’ve noticed tremendous improvements; I feel so much better. It’s remarkable that it is a natural product, especially since my bone pain has greatly diminished.
Leg Cramps details
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 2 Researches
2
USERS' SCORE
Good
Based on 1 Review
8.6
4
We assessed the impact of vitamin D on leg cramps experienced during pregnancy, referring to data from various studies. One of the key findings was that vitamin D treatment showed little to no difference when it came to reducing the frequency of leg cramps.
In a trial involving 84 women, participants who received vitamin D did not see significant changes in the frequency of leg cramps after three weeks or six weeks post-treatment. This suggests that, while vitamin D is often discussed in the context of health benefits, its effectiveness for leg cramps specifically might be quite limited.
Overall, the evidence we reviewed highlights the need for caution. The findings suggest that vitamin D may not be a viable treatment option for managing leg cramps during pregnancy, indicating a need for more robust research in this area.
In a trial involving 84 women, participants who received vitamin D did not see significant changes in the frequency of leg cramps after three weeks or six weeks post-treatment. This suggests that, while vitamin D is often discussed in the context of health benefits, its effectiveness for leg cramps specifically might be quite limited.
Overall, the evidence we reviewed highlights the need for caution. The findings suggest that vitamin D may not be a viable treatment option for managing leg cramps during pregnancy, indicating a need for more robust research in this area.
9.5
Improved health
Most Useful Review
It took two months, but my health has improved; the leg cramps have ceased. My Vitamin D level was 80 recently. Unfortunately, I did not get tested prior to the consultation, but I will repeat the test in three months.
Bronchitis details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 1 Review
8.6
8
Vitamin D links to bronchiolitis severity
The Relationship between Bronchiolitis Severity and Vitamin D Status.
Most Relevant Research
We explored the connection between vitamin D levels and the severity of acute bronchiolitis in infants, a condition primarily triggered by viral infections in children under the age of two. Our study involved 182 children with bronchiolitis, focusing on assessing disease severity using the Modified Tal Scoring System while also evaluating their serum vitamin D levels.
Our findings revealed that a significant number of infants, about 47.8%, had low vitamin D levels, indicating either deficiency or insufficiency. We observed that infants with lower vitamin D were more likely to experience severe cases of bronchiolitis. Additionally, those who required admission to the intensive care unit had an even higher frequency of vitamin D deficiencies.
This research suggests a strong link between vitamin D deficiency and severe bronchiolitis, emphasizing that checking vitamin D levels prior to the bronchiolitis season and providing adequate supplementation could potentially offer protective benefits for young children against this illness.
Our findings revealed that a significant number of infants, about 47.8%, had low vitamin D levels, indicating either deficiency or insufficiency. We observed that infants with lower vitamin D were more likely to experience severe cases of bronchiolitis. Additionally, those who required admission to the intensive care unit had an even higher frequency of vitamin D deficiencies.
This research suggests a strong link between vitamin D deficiency and severe bronchiolitis, emphasizing that checking vitamin D levels prior to the bronchiolitis season and providing adequate supplementation could potentially offer protective benefits for young children against this illness.
9.5
No illnesses anymore
Most Useful Review
I absolutely adore this D3! My doctor recommended a D3 supplement due to my low levels. This choice has transformed my energy levels; I no longer need my daily 2-3 hour naps, as I feel energised all day. Previously, I was prone to various illnesses like sinus infections, sore throats, and bronchitis. Since starting this in September, I’ve remained entirely well! I genuinely feel fantastic! This product has proven to be the only effective D3 for me, allowing me to experience remarkable changes.
Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 1 Review
8.6
5
Vitamin D's role in breast disease
Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study.
Most Relevant Research
We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer.
During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health.
Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions.
At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk.
During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health.
Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions.
At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk.
9.5
Trusted medical approval
Most Useful Review
I have been using Garden of Life Raw D3 since my breast cancer surgery in 2009. Both my regular oncologist and my naturopathic oncologist endorse this product, and I find it very affordable.
Cold details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.8
USERS' SCORE
Good
Based on 1 Review
8.6
8
Vitamin D reduces cold severity
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
Most Relevant Research
We explored the connection between vitamin D levels and upper respiratory tract infections (URTIs) among military recruits during their training. This observation spanned across different seasons and included over 1,600 recruits. Our aim was to understand how achieving sufficient vitamin D levels could potentially impact the frequency and severity of colds among physically active individuals.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
10
Colds eliminated completely
Most Useful Review
I absolutely love this D3! My doctor recommended it for my low D3 levels, and I couldn’t be happier with my choice. I wake up energised and haven’t needed naps during the day. Previously, I would frequently get sick, experiencing colds and other illnesses every autumn and winter. Remarkably, since beginning this in September, I haven’t been sick at all. I feel fantastic!
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Good
Based on 1 Review
8.6
8
Vitamin D reduces headache risk
New evidence that vitamin D prevents headache: a bidirectional two-sample Mendelian randomization analysis.
Most Relevant Research
We explored the potential connection between vitamin D levels and headaches through a thorough investigation using two-sample Mendelian randomization analysis. Our goal was to determine if there’s a causal relationship between high vitamin D levels and the risk of experiencing headaches.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
9.5
Headaches alleviated
Most Useful Review
Vitamin D transformed my life! I consulted a doctor for arthritis due to excruciating bone pain, which was ultimately revealed as an extreme vitamin D deficiency. Since taking this supplement, I've felt significantly better and far healthier overall.
Hypothyroidism details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
USERS' SCORE
Good
Based on 1 Review
8.5
9
Vitamin D improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
Most Relevant Research
We conducted a thorough exploration of how vitamin D supplementation can affect hypothyroidism, particularly in patients with Hashimoto's thyroiditis (HT). Our findings draw from a meta-analysis of twelve randomized controlled trials, involving a total of 862 participants. These studies compared the effects of vitamin D against placebo or no treatment, focusing on various thyroid function indicators and autoantibodies.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
8.8
Supports thyroid health
Most Useful Review
I regularly consume Vitamin D due to symptoms of hypothyroidism, as well as to support my immune and hormonal systems. I prefer products from Garden of Life, but their prices sometimes hinder my frequent purchases. I recommend this product and wish everyone good health!
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
High-dose vitamin D reduces anxiety
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Most Relevant Research
We conducted a study to understand how high-dose vitamin D supplementation might impact anxiety levels, particularly in patients experiencing post-COVID symptoms. In our double-blind, randomized controlled trial, we enrolled 80 individuals dealing with fatigue or neuropsychiatric issues after COVID-19.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
8.3
Effective for anxiety
Most Useful Review
Big pill! I like it, and it's greatly aiding my anxiety and depression. I adore Garden of Life products!
Arthritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 1 Review
8.5
8
Vitamin D aids rheumatoid arthritis
The role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review.
Most Relevant Research
We explored how vitamin D plays a role in managing rheumatoid arthritis (RA), a condition that causes joint inflammation and discomfort. It's been found that many people with RA often suffer from vitamin D deficiency, which may worsen their symptoms and overall disease severity.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively.
9
Life-changing improvement
Most Useful Review
Love it! Vitamin D has transformed my life! I consulted a doctor about my arthritis as my bones ached severely, causing me excruciating pain. I discovered I was extremely deficient in vitamin D. Since taking this supplement, I have felt immensely better and appreciate its natural composition.
Breast Cancer details
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.3
USERS' SCORE
Good
Based on 1 Review
8.5
8
Vitamin D and breast cancer link
Umbrella Review on the Relationship Between Vitamin D Intake and Cancer.
Most Relevant Research
We examined the relationship between vitamin D intake and breast cancer, delving into how this vitamin may play a role in prevention and management. The findings suggest that vitamin D may have a protective effect, potentially lowering the risk of developing breast cancer.
While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.
Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.
Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.
Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.
Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
8.8
Quality supplement affirmed
Most Useful Review
I've been using Garden of Life Raw D3 since having surgery for breast cancer in 2009. Both my oncologists confirm its quality, and the price is very reasonable.
Pneumonia details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Completely healthy
Most Useful Review
I love this D3! I had low D3 levels, so my doctor advised supplementation. I feel so energetic now; I used to need daily naps, but I haven't felt exhausted at all since starting this. I no longer get sick from colds, bronchitis, pneumonia, or any other illness during fall and winter. I can finally enjoy life again, thanks to this wonderful product!
Sore Throat details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Improves overall health
Most Useful Review
LOVE this D3! I had low D3, and my doctor recommended this supplement. I am so pleased I chose it! I now wake up with energy all day long without needing naps. Previously, I suffered from numerous illnesses including sinus infections and sore throats during the fall and winter. Since starting this in September, I haven't been sick at all. It truly is a great product.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
USERS' SCORE
Good
Based on 7 Reviews
8.3
9.5
Vitamin D3 aids autoimmune thyroiditis
Supplementation with active vitamin D3 ameliorates experimental autoimmune thyroiditis in mice by modulating the differentiation and functionality of intrathyroidal T-cell subsets.
Most Relevant Research
We observed that vitamin D3 supplementation may play a significant role in managing autoimmune thyroiditis, a condition often marked by thyroid inflammation. In this study, researchers induced autoimmune thyroiditis in female mice and administered vitamin D3 to evaluate its effects on the disease.
After eight weeks of treatment, the results showed a notable reduction in thyroid damage and lower levels of thyroid autoantibodies in the mice receiving vitamin D3. Specifically, the vitamin appeared to inhibit the activity of certain inflammatory immune cells, which are typically elevated in autoimmune conditions. At the same time, it seemed to support the activity of regulatory immune cells that help keep inflammation in check.
This study highlights the potential of vitamin D3 as a therapeutic option to mitigate the effects of autoimmune thyroiditis, suggesting that it could help balance the immune response in affected individuals. As researchers continue to delve into the role of vitamin D in autoimmune disorders, findings like these support the notion that maintaining adequate vitamin D levels might be crucial for immune health.
After eight weeks of treatment, the results showed a notable reduction in thyroid damage and lower levels of thyroid autoantibodies in the mice receiving vitamin D3. Specifically, the vitamin appeared to inhibit the activity of certain inflammatory immune cells, which are typically elevated in autoimmune conditions. At the same time, it seemed to support the activity of regulatory immune cells that help keep inflammation in check.
This study highlights the potential of vitamin D3 as a therapeutic option to mitigate the effects of autoimmune thyroiditis, suggesting that it could help balance the immune response in affected individuals. As researchers continue to delve into the role of vitamin D in autoimmune disorders, findings like these support the notion that maintaining adequate vitamin D levels might be crucial for immune health.
9.5
Enhanced well-being
Most Useful Review
After two weeks of taking one capsule daily, I noticed an increase in my energy levels, making mornings easier. My vitamin D rose to 28.2 ng/ml, and I feel much healthier now.
Hives details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
USERS' SCORE
Good
Based on 1 Review
8.2
9.5
Vitamin D may alleviate chronic hives
Vitamin D treatment for chronic urticaria: a case report.
Most Relevant Research
We explored the intriguing connection between vitamin D and chronic hives, also known as chronic urticaria. This condition involves recurring itchy welts that can be quite frustrating, especially when the triggers are often elusive. In this case, we observed a 14-year-old boy suffering from persistent hives that weren’t responding to conventional treatments. Thankfully, during his medical evaluation, we discovered he had a vitamin D deficiency.
The boy underwent high-dose vitamin D replenishment, which led to a remarkable and swift improvement in his symptoms. This incident raises an important question about the potential role of vitamin D in both the development and treatment of chronic urticaria. While there’s some evidence suggesting a linked relationship, measuring vitamin D levels and providing supplementation aren’t standard practices in diagnosing or treating this condition yet.
Although our findings indicate that vitamin D might help some patients, we remain cautious about recommending routine screening for vitamin D deficiency in those with chronic urticaria. More research is needed to determine how cost-effective such screenings would be for this condition. Overall, this case sheds light on the possibility that vitamin D could play a significant role in managing chronic hives for certain individuals.
The boy underwent high-dose vitamin D replenishment, which led to a remarkable and swift improvement in his symptoms. This incident raises an important question about the potential role of vitamin D in both the development and treatment of chronic urticaria. While there’s some evidence suggesting a linked relationship, measuring vitamin D levels and providing supplementation aren’t standard practices in diagnosing or treating this condition yet.
Although our findings indicate that vitamin D might help some patients, we remain cautious about recommending routine screening for vitamin D deficiency in those with chronic urticaria. More research is needed to determine how cost-effective such screenings would be for this condition. Overall, this case sheds light on the possibility that vitamin D could play a significant role in managing chronic hives for certain individuals.
5.5
Possible allergic reaction
Most Useful Review
Although this brand is popular, I suspect I experienced an allergic reaction, manifesting as red rashes or hives. I cannot confirm it fully but it appears to be the likely cause at this stage.
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.4
9
Vitamin D counteracts blood clotting
Vitamin D Inhibits IL-6 Pro-Atherothrombotic Effects in Human Endothelial Cells: A Potential Mechanism for Protection against COVID-19 Infection?
Most Relevant Research
Our research focused on understanding how Vitamin D (VitD) might influence blood clotting, especially in the context of COVID-19. We found that when human endothelial cells were exposed to IL-6—an inflammatory cytokine associated with severe COVID-19—it led to dysfunction in these cells. This dysfunction was marked by increased levels of Tissue Factor (TF) and cell adhesion molecules (CAMs), which promote blood clotting.
Remarkably, when we treated these endothelial cells with VitD, we observed a reversal of these harmful effects. VitD appeared to inhibit the expression of TF and CAMs and even modulated the levels of the ACE2 receptor, which is crucial for the entry of the virus into cells. Our findings suggest that VitD could play a protective role against the blood clotting complications associated with COVID-19 by counteracting IL-6's effects on endothelial cells.
Overall, this study paves the way for further research into VitD as a potential therapeutic option for mitigating thrombotic risks in COVID-19 patients.
Remarkably, when we treated these endothelial cells with VitD, we observed a reversal of these harmful effects. VitD appeared to inhibit the expression of TF and CAMs and even modulated the levels of the ACE2 receptor, which is crucial for the entry of the virus into cells. Our findings suggest that VitD could play a protective role against the blood clotting complications associated with COVID-19 by counteracting IL-6's effects on endothelial cells.
Overall, this study paves the way for further research into VitD as a potential therapeutic option for mitigating thrombotic risks in COVID-19 patients.
9.5
Improved vitamin D
Most Useful Review
Works well - my blood test numbers improved significantly within two months, indicating that it absorbs well. I recommend it to anyone seeking a good vitamin D supplement.
