Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Thiamin (B1 from culture of S.cerevisiae)
5 mg
417%
Riboflavin (B2 from culture of S. cerevisiae)
10 mg 
769%
Niacin (as Niacinamide from culture of S. cerevisiae)
45 mg 
281%
Vitamin B6 (from culture of S. cerevisiae)
10 mg 
588%
Folate (from culture of S. cerevisiae)
450 mcg DFE
113%
Vitamin B12 (as Methylcobalamin from culture of S. cerevisiae)
133 mcg 
5542%
Biotin (from culture of S. cerevisiae)
325 mcg 
1083%
Pantothenic Acid (from culture of S. cerevisiae)
45 mg
900%
RAW Organic Fruit & Vegetable Blend
360 mg
+
RAW Probiotic & Enzyme Blend
60 mg
+

Top Medical Research Studies

We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.

We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
Read More
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.

The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.

Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
Read More
9
Benfotiamine shows cardiovascular promise
We examined how benfotiamine could help protect hearts from damage due to acute myocardial infarction. In a rat model, heart injury was induced using isoproterenol. Benfotiamine was given both before and after this treatment to see if it could reduce the damage.

While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
Read More

Most Useful Reviews

9
Reduced heart rate
29 people found this helpful
Thanks to the manufacturer, I've been saved from tachycardia. A friend introduced me to these vitamins after I was prescribed a sedative following a nervous system issue. Despite months on the sedative, I experienced internal tension and severe tachycardia. After taking these vitamins for a few days, my pulse returned to normal. I now take them during stress and they dissolve well in water.
Read More
9
Migraine relief
12 people found this helpful
I take this supplement daily, albeit half the dosage due to high B vitamin norms. It has helped smooth my skin and surprisingly blocked my migraine attacks. I used to suffer from severe migraines, particularly before my periods, but after two months on this, I've had no migraines. I even shared it with my mother during her headache, and it provided relief.
Read More
7.5
Blood pressure stability
2 people found this helpful
I've given this complex to my dad, who has diabetes and hypertension. When he takes it, his sugar and blood pressure normalise, and he alternates with omega and magnesium. I choose this complex because it's the best "raw" vitamin option available.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
  • All Researches
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.

We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
Read More
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.

The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.

Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
Read More
9
Benfotiamine shows cardiovascular promise
We examined how benfotiamine could help protect hearts from damage due to acute myocardial infarction. In a rat model, heart injury was induced using isoproterenol. Benfotiamine was given both before and after this treatment to see if it could reduce the damage.

While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
Read More
8
D-pinitol shows potential heart protection
We examined the potential of D-pinitol to protect against heart damage caused by isoproterenol in Swiss albino mice. The mice were divided into eight groups, receiving various doses of D-pinitol alongside isoproterenol or other treatments.

We found that higher doses (50mg and 100mg) of D-pinitol significantly reduced markers of oxidative stress and inflammation, improving heart health. However, the lower dose (25mg) did not show any meaningful benefits. Overall, our findings suggest D-pinitol may have protective effects against heart damage.
Read More
We investigated how folic acid (FA) could protect against heart injury caused by isoprenaline (ISO) in rats. Over a week, the rats were given FA before being exposed to ISO, which is known to induce heart muscle damage.

The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced heart rate
29 people found this helpful
Thanks to the manufacturer, I've been saved from tachycardia. A friend introduced me to these vitamins after I was prescribed a sedative following a nervous system issue. Despite months on the sedative, I experienced internal tension and severe tachycardia. After taking these vitamins for a few days, my pulse returned to normal. I now take them during stress and they dissolve well in water.
Read More
9
Migraine relief
12 people found this helpful
I take this supplement daily, albeit half the dosage due to high B vitamin norms. It has helped smooth my skin and surprisingly blocked my migraine attacks. I used to suffer from severe migraines, particularly before my periods, but after two months on this, I've had no migraines. I even shared it with my mother during her headache, and it provided relief.
Read More
7.5
Blood pressure stability
2 people found this helpful
I've given this complex to my dad, who has diabetes and hypertension. When he takes it, his sugar and blood pressure normalise, and he alternates with omega and magnesium. I choose this complex because it's the best "raw" vitamin option available.
Read More
2
Increased heartbeat
After taking this product, I noticed my heart beating faster than usual. Although there was no discomfort, I do not plan to repurchase.
Read More

Frequently Asked Questions

9
Reduced heart rate
29 people found this helpful
Thanks to the manufacturer, I've been saved from tachycardia. A friend introduced me to these vitamins after I was prescribed a sedative following a nervous system issue. Despite months on the sedative, I experienced internal tension and severe tachycardia. After taking these vitamins for a few days, my pulse returned to normal. I now take them during stress and they dissolve well in water.
9
Migraine relief
12 people found this helpful
I take this supplement daily, albeit half the dosage due to high B vitamin norms. It has helped smooth my skin and surprisingly blocked my migraine attacks. I used to suffer from severe migraines, particularly before my periods, but after two months on this, I've had no migraines. I even shared it with my mother during her headache, and it provided relief.
7.5
Blood pressure stability
2 people found this helpful
I've given this complex to my dad, who has diabetes and hypertension. When he takes it, his sugar and blood pressure normalise, and he alternates with omega and magnesium. I choose this complex because it's the best "raw" vitamin option available.
2
Increased heartbeat
After taking this product, I noticed my heart beating faster than usual. Although there was no discomfort, I do not plan to repurchase.
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.

We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.

The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.

Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
We investigated how folic acid (FA) could protect against heart injury caused by isoprenaline (ISO) in rats. Over a week, the rats were given FA before being exposed to ISO, which is known to induce heart muscle damage.

The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
7
Folate may reduce heart risks
We explored how dietary intakes of folate, vitamin B6, and vitamin B12 impact heart disease and overall cardiovascular health. Analyzing data from over 115,000 individuals with no prior heart conditions, we found that higher folate consumption was associated with lower risks of cardiovascular events and mortality. Specifically, each increase in folate was linked to a 5% reduction in total cardiovascular incidents and a 10% decline in related deaths. This highlights folate's potential role in preventing heart issues rather than confirming benefits from other B vitamins in this context.

References

  1. Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413
  2. Sobot T, Bajic Z, Skrbic R, Uletilovic S, Mandic-Kovacevic N, et al. Effect of folic acid on isoprenaline-induced myocardial injury in rats. Physiol Int. 2024;111:80. doi:10.1556/2060.2023.00291
  3. Tannous C, Ghali R, Karoui A, Habeichi NJ, Amin G, et al. Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction. Cardiovasc Drugs Ther. 2024;38:1385. doi:10.1007/s10557-023-07525-1
  4. Zhang B, Dong H, Xu Y, Xu D, Sun H, et al. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort. Eur J Clin Nutr. 2023;77:299. doi:10.1038/s41430-022-01206-2
  5. Khan A, Iqubal A, Wasim M, Syed MA, Haque SE. D-pinitol attenuates isoproterenol-induced myocardial infarction by alleviating cardiac inflammation, oxidative stress and ultrastructural changes in Swiss albino mice. Clin Exp Pharmacol Physiol. 2022;49:1232. doi:10.1111/1440-1681.13703
  6. Evens L, Beliën H, D'Haese S, Haesen S, Verboven M, et al. Combinational Therapy of Cardiac Atrial Appendage Stem Cells and Pyridoxamine: The Road to Cardiac Repair?. Int J Mol Sci. 2021;22. doi:10.3390/ijms22179266
  7. Ahmed LA, Hassan OF, Galal O, Mansour DF, El-Khatib A. Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, in isoproterenol-induced myocardial infarction in rats. PLoS One. 2020;15:e0232413. doi:10.1371/journal.pone.0232413
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