We explored the effectiveness of a dietary supplement combining red yeast rice and other natural compounds for lowering cholesterol in children with high cholesterol.
In a study involving 84 children and adolescents, the supplement significantly decreased total cholesterol and harmful LDL cholesterol after 6 and 16 months. However, there were no notable changes in HDL cholesterol or triglycerides.
Interestingly, those who had been taking phytosterols saw even better results after starting the supplement. Overall, this treatment appears safe and effective, but more research is needed to confirm these findings in larger groups.
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Niacin lowers cholesterol in diabeticsPlasma niacin is inversely associated with hyperlipidemia in participants with diabetes among Chinese adults.
Moderate relevance to cholesterol management
We aimed to understand how plasma niacin, an important B vitamin, relates to high cholesterol levels, particularly in individuals with diabetes. In our study involving 2,647 participants, we found that higher levels of plasma niacin were linked to a significantly lower risk of hyperlipidemia in those with diabetes.
This connection didn’t hold true for nondiabetic participants. Interestingly, our results showed consistent benefits across various subgroups, indicating that niacin might play a promising role in cholesterol management for diabetic patients, though more research is necessary for those without diabetes.
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Monacolin K significantly lowers LDL-CLow daily dose of 3 mg monacolin K from RYR reduces the concentration of LDL-C in a randomized, placebo-controlled intervention.
Highly relevant cholesterol management study
We aimed to explore whether a low daily dose of monacolin K from red yeast rice (RYR) could help lower cholesterol levels. In a well-designed, randomized, double-blind, placebo-controlled study, 142 participants with high cholesterol took either RYR or a placebo for 12 weeks.
Participants taking RYR saw a significant drop in low-density lipoprotein cholesterol (LDL-C) by 14.8% and total cholesterol by 11.2%. Impressively, over half reached the recommended LDL-C levels. However, those who received the placebo showed no notable changes.
This study suggests that a small daily dose of monacolin K can be effective in helping manage cholesterol levels.
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Effective cholesterol reduction notedNutraceuticals for Serum Lipid and Blood Pressure Control in Hypertensive and Hypercholesterolemic Subjects at Low Cardiovascular Risk.
High relevance to cholesterol treatment
We examined the effectiveness of nutraceuticals in lowering cholesterol levels and blood pressure for patients with high cholesterol and hypertension. Over six months, 66 participants took a daily tablet containing red yeast rice, policosanol, berberine, folic acid, and coenzyme Q10 alongside usual diet management.
The results showed significant reductions in total cholesterol and LDL cholesterol, while HDL levels remained unchanged. Importantly, no improvements were observed in the control group. Overall, these nutraceuticals appear safe and effective for enhancing lipid profiles in this specific patient group.
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Niacin reduces cholesterol and oxidative stressNiacin administration significantly reduces oxidative stress in patients with hypercholesterolemia and low levels of high-density lipoprotein cholesterol.
Relevance score reflects significant findings
We examined how niacin (vitamin B3) impacts cholesterol levels and oxidative stress in patients with low HDL cholesterol. In this study, 17 participants with high cholesterol received niacin treatment over 12 weeks, while 8 healthy individuals served as controls.
The results were promising. We discovered a significant boost in HDL cholesterol and a drop in triglycerides among the patients. More importantly, niacin also reduced markers of oxidative stress, suggesting its benefits extend beyond just cholesterol management. However, CRP levels remained unchanged.
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