Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 9 Reviews
8.1
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Thiamin (B1 from culture of S.cerevisiae)
5 mg
417%
Riboflavin (B2 from culture of S. cerevisiae)
10 mg 
769%
Niacin (as Niacinamide from culture of S. cerevisiae)
45 mg 
281%
Vitamin B6 (from culture of S. cerevisiae)
10 mg 
588%
Folate (from culture of S. cerevisiae)
450 mcg DFE
113%
Vitamin B12 (as Methylcobalamin from culture of S. cerevisiae)
133 mcg 
5542%
Biotin (from culture of S. cerevisiae)
325 mcg 
1083%
Pantothenic Acid (from culture of S. cerevisiae)
45 mg
900%
RAW Organic Fruit & Vegetable Blend
360 mg
+
RAW Probiotic & Enzyme Blend
60 mg
+

Top Medical Research Studies

We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
8
ImproWin® aids gastric ulcer healing
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.

Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More
8
Folic acid has mixed effects
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.

We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.

Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
Read More

Most Useful Reviews

9
Quick relief achieved
1 people found this helpful
It's beneficial; I take out the contents and mix it with other superfoods for a drink. Using this when I have a mouth ulcer leads to a quick reduction in discomfort, proving to be quite helpful.
Read More
8
Enhanced digestion
1 people found this helpful
Works great! Love it! This product has not only helped with my energy levels but also my stomach issues. I was surprised by the increase in alertness during the day and no longer experience the afternoon slump. It has aided my digestion too. I’ve had peptic ulcers in the past and required long-term prilosec. This product helps my digestion and keeps me more regular. Great product! I will recommend it to all my friends.
Read More
9
Ulcers no longer recurring
I repurchased this item. Since I began taking vitamin B, my mouth ulcers have not reappeared; I think it’s brilliant.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
  • All Researches
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.

Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.

Various robust models reinforced this result, showing consistent outcomes across different analyses.

Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Read More
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
9
Effective ulcer treatment in diabetes
We explored the effects of Luffa acutangula extracts on gastric ulcers in diabetic rats. By inducing non-insulin dependent diabetes mellitus (NIDDM) and then creating gastric ulcers, we evaluated the extracts' potential for healing.

The results showed that the methanolic extract significantly boosted healing, improving protective mucosal glycoproteins and antioxidant levels. This was better than the aqueous extract and standard treatments.

Overall, Luffa acutangula appears to offer promising support for treating gastric ulcers in diabetes, highlighting its dual action in managing both conditions.
Read More
9
Effective treatment for oral ulcers
We explored the effectiveness of mecobalamin and vitamin E in treating recurrent oral ulcers. In a study with 58 patients, those receiving both treatments showed significantly improved healing times and reduced symptoms compared to the control group. They experienced longer periods without ulcer flare-ups and better quality of life scores. Both groups felt pain relief, but the test group had more noticeable benefits. This finding suggests that mecobalamin and vitamin E can be a valuable addition to ulcer treatment, enhancing both comfort and recovery.
Read More
8
ImproWin® aids gastric ulcer healing
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.

Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Quick relief achieved
1 people found this helpful
It's beneficial; I take out the contents and mix it with other superfoods for a drink. Using this when I have a mouth ulcer leads to a quick reduction in discomfort, proving to be quite helpful.
Read More
8
Enhanced digestion
1 people found this helpful
Works great! Love it! This product has not only helped with my energy levels but also my stomach issues. I was surprised by the increase in alertness during the day and no longer experience the afternoon slump. It has aided my digestion too. I’ve had peptic ulcers in the past and required long-term prilosec. This product helps my digestion and keeps me more regular. Great product! I will recommend it to all my friends.
Read More
9
Ulcers no longer recurring
I repurchased this item. Since I began taking vitamin B, my mouth ulcers have not reappeared; I think it’s brilliant.
Read More
9
Visible efficacy noted
I sense that it works. I bought this as a preventive measure against mouth ulcers and occasional pimples. Although pricier than other B vitamins, the effect is remarkably clear. I usually take one tablet after dinner, and by the next day, both my mouth ulcers and rough skin show improvement. I believe the vitamin B group balance suits me well. Unlike other B vitamins, which can cause stomach upset after consecutive use, I find this one a useful supplement to keep handy.
Read More
7.5
Fewer ulcers noted
1 people found this helpful
Excellent! Initially, I was worried about the capsules being too large, but I was relieved to find they were easy to swallow. They have no taste or smell, making them simple to consume. Mouth ulcers used to trouble me, but since I began taking this a month ago, I’ve noticed a decrease in their occurrence, which makes me quite happy!
Read More

Frequently Asked Questions

9
Quick relief achieved
1 people found this helpful
It's beneficial; I take out the contents and mix it with other superfoods for a drink. Using this when I have a mouth ulcer leads to a quick reduction in discomfort, proving to be quite helpful.
9
Visible efficacy noted
I sense that it works. I bought this as a preventive measure against mouth ulcers and occasional pimples. Although pricier than other B vitamins, the effect is remarkably clear. I usually take one tablet after dinner, and by the next day, both my mouth ulcers and rough skin show improvement. I believe the vitamin B group balance suits me well. Unlike other B vitamins, which can cause stomach upset after consecutive use, I find this one a useful supplement to keep handy.
7.5
Fewer ulcers noted
1 people found this helpful
Excellent! Initially, I was worried about the capsules being too large, but I was relieved to find they were easy to swallow. They have no taste or smell, making them simple to consume. Mouth ulcers used to trouble me, but since I began taking this a month ago, I’ve noticed a decrease in their occurrence, which makes me quite happy!
9
Ulcers no longer recurring
I repurchased this item. Since I began taking vitamin B, my mouth ulcers have not reappeared; I think it’s brilliant.
7.5
Child's improvement noted
Excellent vitamins! I specifically bought these for my child as a supplement. Taking one pill daily has significantly improved my child’s oral ulcers.
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.

Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.

Various robust models reinforced this result, showing consistent outcomes across different analyses.

Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
8
Folic acid has mixed effects
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.

We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.

Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.

Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.

However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
8
Nicotinamide shows ulcer protection
We explored the effects of nicotinamide on gastric ulcers caused by indomethacin in a laboratory setting. Using a well-established model, we compared the treatment of nicotinamide with sucralfate, a known antiulcer drug.

Our findings revealed that nicotinamide significantly reduced the severity of gastric lesions. It also helped restore vital biochemical parameters affected by the ulcer-inducing drug.

The protective effect of nicotinamide appears to stem from its ability to conserve gastric mucus and nitric oxide, improve gastric microvascular permeability, and exert antioxidant actions.

References

  1. Li F, Huang F, Tang Y, Zhang F, Jiang H, et al. Causal association of folic acid supplementary therapy and gastric ulcer: a Mendelian randomisation study. Br J Nutr. 2024;132:1348. doi:10.1017/S0007114524002368
  2. Shokati Sayyad M, Khanjani MH, Amirbeik M, Seyedabadi M, Talebpour Amiri F, et al. The protective effect of benfotiamine on gastric ulcers in male rats: an experimental study. J Mol Histol. 2024;55:863. doi:10.1007/s10735-024-10237-x
  3. Hellings IR, Larsen S. ImproWin® in the treatment of gastric ulceration of the squamous mucosa in trotting racehorses. Acta Vet Scand. 2014;56:13. doi:10.1186/1751-0147-56-13
  4. Ajeigbe K, Oladejo E, Emikpe B, Asuk A, Olaleye S. The dual modulatory effect of folic acid supplementation on indomethacin-induced gastropathy in the rat. Turk J Gastroenterol. 2012;23:639.
  5. Pimple BP, Kadam PV, Patil MJ. Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: role of gastric mucosal glycoproteins and antioxidants. Asian Pac J Trop Med. 2012;5:610. doi:10.1016/S1995-7645(12)60126-6
  6. Abdallah DM. Nicotinamide alleviates indomethacin-induced gastric ulcers: a novel antiulcer agent. Eur J Pharmacol. 2010;627:276. doi:10.1016/j.ejphar.2009.10.037
  7. Cui J, Lin W, Ma X, Wang J. Clinical Evaluation and Therapeutic Effects of Combination Treatment with Mecobalamin + Vitamin E in Recurrent Oral Ulcer. Clin Ther. 2022;44:123. doi:10.1016/j.clinthera.2021.10.015
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