Vitamin C may lower hypothyroidism riskAssociation between total vitamin C intake and hypothyroidism among Hashimoto thyroiditis: National Health and Nutrition Examination Survey, 2007-2012.
Direct focus on vitamin C's effects
This study aimed to explore whether vitamin C intake could have an impact on hypothyroidism in individuals with Hashimoto thyroiditis (HT). We analyzed data from the National Health and Nutrition Examination Survey, focusing on participants from 2007 to 2012.
Our findings revealed an interesting association. We observed that higher total vitamin C intake was linked to a lower likelihood of hypothyroidism in those with HT. Specifically, individuals in the highest quartile of vitamin C intake had about 60% lower odds of experiencing hypothyroidism compared to those in the lowest quartile. This suggests that a greater intake of vitamin C, ranging from 4.57 to 1258.9 mg per day, might be beneficial for those affected by this condition.
Additionally, this association held true across different age groups and genders. Overall, we found that increasing vitamin C consumption might offer protective effects against the onset of hypothyroidism in Hashimoto thyroiditis patients.
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We studied how low-grade inflammation might lead to endothelial dysfunction in individuals with subclinical hypothyroidism (sHT) related to Hashimoto's thyroiditis. Our research included 53 patients diagnosed with sHT and 45 healthy individuals for comparison.
We assessed the participants' blood flow response to a substance called acetylcholine (Ach), which helps widen blood vessels. This response was measured under various scenarios, including the administration of vitamin C, a well-known antioxidant.
Interestingly, we found that while Vitamin C seemed beneficial in improving the blood flow response in sHT patients, its effects disappeared after administering indomethacin, a nonsteroidal anti-inflammatory drug. This suggests that vitamin C's role might be influenced by other factors related to inflammation and oxidative stress in these patients.
Overall, our findings indicate that while vitamin C may offer some advantages in enhancing vascular function, it isn't a standalone solution for managing endothelial dysfunction in those with Hashimoto’s.
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