5/11/2025
Last update
5/11/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.7
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.6
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Vitamin A (as beta-carotene from nutrient media)
900 mcg
100%
Vitamin D (as D3 cholecalciferol from nutrient media)
50 mcg (2,000 IU)
250%
Vitamin E (as d-alpha tocopherol from sunflower oil)
125 mg
833%
Vitamin K (as phylloquinone from nutrient media)
72 mcg
60%
Selenium (from brown rice chelate)
61 mcg
111%
Raw Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), OrganicCarrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry(fruit), Organic Tart Cherry (fruit), Organic Blackberry (fruit), Organic Green BellPepper (fruit), Organic Brussels Sprout (leaf), Organic Blueberry (fruit), OrganicGinger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem),Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd),Organic Celery (stalk), Organic Asparagus (flower & stem)
500 mg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain,Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, Bacillus coagulans SNZ 1969™ (500 Million CFU at time of expiration)
56 mg
+
Mixed Tocopherols Powder
4 mg
+
Top Medical Research Studies
2
We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Read More
9
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
Read More
8
Vitamin E reduces heart attack risk
We explored the effects of dietary vitamin E on heart attack and overall health by analyzing data from over 39,000 participants in the NHANES survey from 2003 to 2018. Our findings indicated that a higher intake of vitamin E was linked to a lower risk of cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Read More
Most Useful Reviews
1
Side effects experienced
5 people found this helpful
My chest hurt, and I did not feel well. This supplement made me feel as if I were about to have a heart attack. My chest felt heavy, and I felt exhausted. After discontinuing this vitamin, I felt more normal in just three days and returned to 100% in a week. I suppose I’m sensitive to something in this supplement.
Read More
8
Heart health support
Omega-3 300 mg supports heart health and is gluten-free. This dietary supplement has passed laboratory tests for EPA and DHA, crucial omega-3 fatty acids for cardiovascular health. The fish oil from 21 Century is a high-quality concentrate, purified at the molecular level and beneficial for heart attack prevention.
Read More
7.5
Supports heart health
Vitamin E significantly aids heart health, particularly for valve issues. I highly recommend it!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.7
- All Researches
9
We explored how an innovative hydrogel enhanced heart repair after a heart attack. This injectable hydrogel includes α-tocopherol, a form of vitamin E. In our study using a rabbit model, we implanted the hydrogel after inducing a heart attack.
Four weeks later, the results were promising. We noticed improved heart function and reduced damage to heart tissue. This suggests that the hydrogel, enriched with vitamin E, plays a vital role in helping the heart recover better after an injury.
Four weeks later, the results were promising. We noticed improved heart function and reduced damage to heart tissue. This suggests that the hydrogel, enriched with vitamin E, plays a vital role in helping the heart recover better after an injury.
Read More
9
β-Cryptoxanthin outperforming vitamin E
We investigated how three antioxidant compounds—β-cryptoxanthin, astaxanthin, and vitamin E—affect heart damage from ischemia-reperfusion injury in mice.
Mice were treated with these compounds before inducing heart injury.
Results showed that all treatments reduced heart damage, but β-cryptoxanthin was the most effective, shrinking heart injury by 60% compared to vitamin E and astaxanthin.
Ultimately, while vitamin E showed some benefits, β-cryptoxanthin stood out in reducing oxidative stress and cellular damage more effectively.
Mice were treated with these compounds before inducing heart injury.
Results showed that all treatments reduced heart damage, but β-cryptoxanthin was the most effective, shrinking heart injury by 60% compared to vitamin E and astaxanthin.
Ultimately, while vitamin E showed some benefits, β-cryptoxanthin stood out in reducing oxidative stress and cellular damage more effectively.
Read More
9
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
Read More
9
We aimed to explore how a combination of quercetin and vitamin E (alpha-tocopherol) may impact heart function in rats experiencing induced heart attacks. After treatment, all the essential heart enzyme levels returned to normal, suggesting these natural compounds might help stabilize heart membranes and reduce damage.
This is particularly hopeful for patients with heart conditions, as the combination proved to be more effective than either quercetin or vitamin E alone.
However, it’s important to note that while results are promising, further studies are necessary to fully understand these effects in humans.
This is particularly hopeful for patients with heart conditions, as the combination proved to be more effective than either quercetin or vitamin E alone.
However, it’s important to note that while results are promising, further studies are necessary to fully understand these effects in humans.
Read More
8
Vitamin E reduces heart attack risk
We explored the effects of dietary vitamin E on heart attack and overall health by analyzing data from over 39,000 participants in the NHANES survey from 2003 to 2018. Our findings indicated that a higher intake of vitamin E was linked to a lower risk of cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
1
Side effects experienced
5 people found this helpful
My chest hurt, and I did not feel well. This supplement made me feel as if I were about to have a heart attack. My chest felt heavy, and I felt exhausted. After discontinuing this vitamin, I felt more normal in just three days and returned to 100% in a week. I suppose I’m sensitive to something in this supplement.
Read More
8
Heart health support
Omega-3 300 mg supports heart health and is gluten-free. This dietary supplement has passed laboratory tests for EPA and DHA, crucial omega-3 fatty acids for cardiovascular health. The fish oil from 21 Century is a high-quality concentrate, purified at the molecular level and beneficial for heart attack prevention.
Read More
7.5
Supports heart health
Vitamin E significantly aids heart health, particularly for valve issues. I highly recommend it!
Read More
Frequently Asked Questions
8
Heart health support
Omega-3 300 mg supports heart health and is gluten-free. This dietary supplement has passed laboratory tests for EPA and DHA, crucial omega-3 fatty acids for cardiovascular health. The fish oil from 21 Century is a high-quality concentrate, purified at the molecular level and beneficial for heart attack prevention.
7.5
Supports heart health
Vitamin E significantly aids heart health, particularly for valve issues. I highly recommend it!
8
Vitamin E reduces heart attack risk
We explored the effects of dietary vitamin E on heart attack and overall health by analyzing data from over 39,000 participants in the NHANES survey from 2003 to 2018. Our findings indicated that a higher intake of vitamin E was linked to a lower risk of cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
8
We explored the effect of vitamin E on heart attack risk by analyzing 16 randomized controlled trials. Our findings show that when taken alone, vitamin E supplementation may significantly decrease the incidence of myocardial infarction, particularly fatal cases. Specifically, the results indicated a reduction from 3.4% in the control group to 3.0% in those receiving vitamin E. However, it appears that combining vitamin E with other antioxidants does not provide any significant benefits for heart health.
9
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
2
We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
9
β-Cryptoxanthin outperforming vitamin E
We investigated how three antioxidant compounds—β-cryptoxanthin, astaxanthin, and vitamin E—affect heart damage from ischemia-reperfusion injury in mice.
Mice were treated with these compounds before inducing heart injury.
Results showed that all treatments reduced heart damage, but β-cryptoxanthin was the most effective, shrinking heart injury by 60% compared to vitamin E and astaxanthin.
Ultimately, while vitamin E showed some benefits, β-cryptoxanthin stood out in reducing oxidative stress and cellular damage more effectively.
Mice were treated with these compounds before inducing heart injury.
Results showed that all treatments reduced heart damage, but β-cryptoxanthin was the most effective, shrinking heart injury by 60% compared to vitamin E and astaxanthin.
Ultimately, while vitamin E showed some benefits, β-cryptoxanthin stood out in reducing oxidative stress and cellular damage more effectively.
References
- Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. 10.1016/j.ijcrp.2024.200340
- Zhang F, Zhang Y, Qian S, Qian X, Jiao J, et al. Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair. ACS Nano. 2024;18:10216. 10.1021/acsnano.4c00509
- Wang T, Xu L. Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study. Nutrients. 2019;11. 10.3390/nu11092153
- Pongkan W, Takatori O, Ni Y, Xu L, Nagata N, et al. β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice. Mol Nutr Food Res. 2017;61. 10.1002/mnfr.201601077
- Loffredo L, Perri L, Di Castelnuovo A, Iacoviello L, De Gaetano G, et al. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis. Nutr Metab Cardiovasc Dis. 2015;25:354. 10.1016/j.numecd.2015.01.008
- Shukla SK, Sharma SB, Singh UR. Pre-treatment with α-tocopherol and Terminalia arjuna ameliorates, pro-inflammatory cytokines, cardiac and apoptotic markers in myocardial infracted rats. Redox Rep. 2015;20:49. 10.1179/1351000214Y.0000000104
- Rodrigo R, Hasson D, Prieto JC, Dussaillant G, Ramos C, et al. The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trial. Trials. 2014;15:192. 10.1186/1745-6215-15-192
- Vardi M, Blum S, Levy AP. Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature. Eur J Intern Med. 2012;23:628. 10.1016/j.ejim.2012.04.009
- Rautiainen S, Akesson A, Levitan EB, Morgenstern R, Mittleman MA, et al. Multivitamin use and the risk of myocardial infarction: a population-based cohort of Swedish women. Am J Clin Nutr. 2010;92:1251. 10.3945/ajcn.2010.29371
- Blum S, Vardi M, Brown JB, Russell A, Milman U, et al. Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics. 2010;11:675. 10.2217/pgs.10.17
- Punithavathi VR, Prince PS. Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats. Life Sci. 2010;86:178. 10.1016/j.lfs.2009.11.021
