Last update
3/18/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Iron (from Ionic Plant Based Minerals)
2 mg
10%
HSO Probiotic Blend (5 Billion CFU)¹Saccharomyces boulardii, Organic Barley Grass², Organic Oat Grass², Lactobacillus plantarum, Bacillus subtilis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus rhamnosus, Bifidobacterium breve, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus acidophilus, Lactobacillus brevis, Bifidobacterium longum, Lactobacillus paracasei
410 mg
+
Ionic Plant Based Minerals
290 mg
+
Top Medical Research Studies
8
We conducted a double-blind, placebo-controlled study to assess how Lactobacillus acidophilus might help with stress-related gastrointestinal issues, particularly nausea. Over three weeks, volunteers received either a probiotic called Probio-Stick or a placebo.
We found that consumption of the probiotics significantly eased nausea and abdominal pain linked to stress. However, it didn't have a notable impact on other symptoms like sleep problems or psychological distress. Overall, our findings suggest that Probio-Stick is effective for alleviating certain gastrointestinal symptoms caused by stress.
We found that consumption of the probiotics significantly eased nausea and abdominal pain linked to stress. However, it didn't have a notable impact on other symptoms like sleep problems or psychological distress. Overall, our findings suggest that Probio-Stick is effective for alleviating certain gastrointestinal symptoms caused by stress.
Read More
7
We investigated whether Saccharomyces boulardii could alleviate nausea and other discomforts during a 14-day treatment for Helicobacter pylori. In our study with 124 patients, half received S. boulardii while the other half received a placebo.
Participants reported improvements in gastrointestinal symptoms, such as diarrhea and epigastric discomfort. However, while S. boulardii helped with treatment tolerability and post-treatment nausea, it did not significantly enhance the overall success rate of eradicating H. pylori.
Participants reported improvements in gastrointestinal symptoms, such as diarrhea and epigastric discomfort. However, while S. boulardii helped with treatment tolerability and post-treatment nausea, it did not significantly enhance the overall success rate of eradicating H. pylori.
Read More
8
We explored the effects of Bifidobacterium lactis HN019 on gut transit time and gastrointestinal symptoms among 100 adults with functional GI issues. Participants took either a high dose, a low dose, or a placebo over 14 days.
Our findings revealed significant improvements in gut transit time and a reduction in GI symptoms for those taking B. lactis compared to the placebo group. Interestingly, the high dose showed more pronounced benefits, leading to fewer symptoms and quicker gut transit.
Overall, we found that this probiotic strain is a safe option that may help alleviate digestive discomfort.
Our findings revealed significant improvements in gut transit time and a reduction in GI symptoms for those taking B. lactis compared to the placebo group. Interestingly, the high dose showed more pronounced benefits, leading to fewer symptoms and quicker gut transit.
Overall, we found that this probiotic strain is a safe option that may help alleviate digestive discomfort.
Read More
Most Useful Reviews
9
Nausea relief during chemo
9 people found this helpful
Garden of Life is the best! I began using these while undergoing chemotherapy for stage 3 breast cancer, where the nausea was unbearable. While not a complete remedy, they significantly reduced my nausea and enhanced my immunity. If I stop taking them, I feel bloated and lethargic; resuming use brings back my energy and well-being. Moreover, if my stomach is upset after eating, two of these make it right again, and I can’t emphasise how phenomenal they are for bowel regularity and digestion. Highly recommend!
Read More
7.5
Nausea decreases significantly
22 people found this helpful
Works for me! Since December 2010, I had a persistent "stomach thing," leading to a lack of appetite and digestive issues, including bouts of nausea. After recalling I had some of these vitamins, I started taking one daily. Within weeks, my appetite and digestion normalised. I also experienced fewer painful episodes of gas after eating. I plan on continuing to take these indefinitely, as the excellent value for health benefits is truly worth it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.3
- All Researches
8
We conducted a double-blind, placebo-controlled study to assess how Lactobacillus acidophilus might help with stress-related gastrointestinal issues, particularly nausea. Over three weeks, volunteers received either a probiotic called Probio-Stick or a placebo.
We found that consumption of the probiotics significantly eased nausea and abdominal pain linked to stress. However, it didn't have a notable impact on other symptoms like sleep problems or psychological distress. Overall, our findings suggest that Probio-Stick is effective for alleviating certain gastrointestinal symptoms caused by stress.
We found that consumption of the probiotics significantly eased nausea and abdominal pain linked to stress. However, it didn't have a notable impact on other symptoms like sleep problems or psychological distress. Overall, our findings suggest that Probio-Stick is effective for alleviating certain gastrointestinal symptoms caused by stress.
Read More
8
We explored the effects of Bifidobacterium lactis HN019 on gut transit time and gastrointestinal symptoms among 100 adults with functional GI issues. Participants took either a high dose, a low dose, or a placebo over 14 days.
Our findings revealed significant improvements in gut transit time and a reduction in GI symptoms for those taking B. lactis compared to the placebo group. Interestingly, the high dose showed more pronounced benefits, leading to fewer symptoms and quicker gut transit.
Overall, we found that this probiotic strain is a safe option that may help alleviate digestive discomfort.
Our findings revealed significant improvements in gut transit time and a reduction in GI symptoms for those taking B. lactis compared to the placebo group. Interestingly, the high dose showed more pronounced benefits, leading to fewer symptoms and quicker gut transit.
Overall, we found that this probiotic strain is a safe option that may help alleviate digestive discomfort.
Read More
8
We examined how adding Saccharomyces boulardii to conventional treatments could aid in eradicating certain gastric infections. Through a thorough search of databases over the past two decades, we focused on outcomes, including nausea and other side effects.
Our findings suggest that incorporating Saccharomyces boulardii significantly enhances eradication rates while also decreasing nausea and other gastrointestinal issues. This gives us hope for better treatment options in battling these prevalent gastric conditions.
Our findings suggest that incorporating Saccharomyces boulardii significantly enhances eradication rates while also decreasing nausea and other gastrointestinal issues. This gives us hope for better treatment options in battling these prevalent gastric conditions.
Read More
8
Saccharomyces boulardii reduces nausea effectively
We explored how Saccharomyces boulardii supplementation, when added to standard triple therapy (STT), can impact children’s nausea during H. pylori treatment. Analyzing data from 15 randomized controlled trials with over 2,000 participants, we found that S. boulardii significantly reduced nausea rates compared to STT alone—down to 12.7% from 21.3%.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
Read More
We conducted a double-blind, placebo-controlled study to see how Saccharomyces boulardii might help in reducing nausea during Helicobacter pylori eradication therapy.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Nausea relief during chemo
9 people found this helpful
Garden of Life is the best! I began using these while undergoing chemotherapy for stage 3 breast cancer, where the nausea was unbearable. While not a complete remedy, they significantly reduced my nausea and enhanced my immunity. If I stop taking them, I feel bloated and lethargic; resuming use brings back my energy and well-being. Moreover, if my stomach is upset after eating, two of these make it right again, and I can’t emphasise how phenomenal they are for bowel regularity and digestion. Highly recommend!
Read More
7.5
Nausea decreases significantly
22 people found this helpful
Works for me! Since December 2010, I had a persistent "stomach thing," leading to a lack of appetite and digestive issues, including bouts of nausea. After recalling I had some of these vitamins, I started taking one daily. Within weeks, my appetite and digestion normalised. I also experienced fewer painful episodes of gas after eating. I plan on continuing to take these indefinitely, as the excellent value for health benefits is truly worth it.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Wu Y, Dong XY, Zhou XZ, Li ZS, Du YQ. Effects of probiotics on gastric microbiota and its precombination with quadruple regimen for Helicobacter pylori eradication. J Dig Dis. 2022;23:462. 10.1111/1751-2980.13138
- Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. 10.1007/s11695-020-04900-x
- Feng JR, Wang F, Qiu X, McFarland LV, Chen PF, et al. Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Eur J Clin Pharmacol. 2017;73:1199. 10.1007/s00228-017-2291-6
- Diop L, Guillou S, Durand H. Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomized trial. Nutr Res. 2008;28:1. 10.1016/j.nutres.2007.10.001
- Han Z, Li Y, Nan X, Zhou T, Li L, et al. Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during eradication: a randomized, double-blind, placebo-controlled trial. Front Nutr. 2024;11:1484646. 10.3389/fnut.2024.1484646
- Michels M, Córneo E, Cucker L, Simon CS, de Jesus GFA, et al. Bifidobacterium lactis CCT 7858 Improves Gastrointestinal Symptoms by Antibiotics Treatment: a Double-Blind, Randomized, Placebo-Controlled Trial. Probiotics Antimicrob Proteins. 2023;15:738. 10.1007/s12602-021-09900-6
- Waller PA, Gopal PK, Leyer GJ, Ouwehand AC, Reifer C, et al. Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scand J Gastroenterol. 2011;46:1057. 10.3109/00365521.2011.584895
- Li M, Xie Y. Efficacy and safety of as an adjuvant therapy for the eradication of : a meta-analysis. Front Cell Infect Microbiol. 2025;15:1441185. 10.3389/fcimb.2025.1441185
- Liu LH, Han B, Tao J, Zhang K, Wang XK, et al. The effect of Saccharomyces boulardii supplementation on Helicobacter pylori eradication in children: a systematic review and meta-analysis of Randomized controlled trials. BMC Infect Dis. 2023;23:878. 10.1186/s12879-023-08896-4
- Naghibzadeh N, Salmani F, Nomiri S, Tavakoli T. Investigating the effect of quadruple therapy with Saccharomyces boulardii or Lactobacillus reuteri strain (DSMZ 17648) supplements on eradication of Helicobacter pylori and treatments adverse effects: a double-blind placebo-controlled randomized clinical trial. BMC Gastroenterol. 2022;22:107. 10.1186/s12876-022-02187-z
- Sirchak YS, Patskun SV, Bedey NV. DYNAMICS OF GASTRIN LEVEL IN PATIENTS WITH DIABETES MELLITUS 2 TYPE AND CHRONIC GASTRITIS AFTER HELICOBACTER PYLORI ERADICATION THERAPY. Wiad Lek. 2020;73:2512. PubMed
- He CX, Kong FT, Liang F, Wang KX, Li H, et al. [Influence of different timing of combined with bismuth quadruple therapy for eradication]. Zhonghua Yi Xue Za Zhi. 2019;99:1731. 10.3760/cma.j.issn.0376-2491.2019.22.010
- Chotivitayatarakorn P, Mahachai V, Vilaichone RK. Effectiveness of 7-Day and 14-Day Moxifloxacin-Dexlansoprazole Based Triple Therapy and Probiotic Supplement for Helicobacter Pylori Eradication in Thai Patients with Non-Ulcer Dyspepsia: A Double-Blind Randomized Placebo-Controlled Study. Asian Pac J Cancer Prev. 2017;18:2839. PubMed
- Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. 10.1016/j.explore.2016.08.015
- Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. 10.1002/14651858.CD004827.pub4
- Szajewska H, Horvath A, Kołodziej M. Systematic review with meta-analysis: Saccharomyces boulardii supplementation and eradication of Helicobacter pylori infection. Aliment Pharmacol Ther. 2015;41:1237. 10.1111/apt.13214
- Zojaji H, Ghobakhlou M, Rajabalinia H, Ataei E, Jahani Sherafat S, et al. The efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of H.pylori: a randomized controlled trial. Gastroenterol Hepatol Bed Bench. 2013;6:S99. PubMed
- Dinleyici EC, Eren M, Dogan N, Reyhanioglu S, Yargic ZA, et al. Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection. Parasitol Res. 2011;108:541. 10.1007/s00436-010-2095-4
- Cindoruk M, Erkan G, Karakan T, Dursun A, Unal S. Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. Helicobacter. 2007;12:309. PubMed
- Cremonini F, Di Caro S, Covino M, Armuzzi A, Gabrielli M, et al. Effect of different probiotic preparations on anti-helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study. Am J Gastroenterol. 2002;97:2744. PubMed
Data last updated:
