Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Moderately Good
Based on 10 Reviews
7
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Vitamin C (from culture of Saccharomyces cerevisiae)
60 mg
67%
Zinc (from Brown Rice Chelate)
30 mg
273%
Raw Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Blueberry (fruit), Organic Ginger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
166 mg
+
Trace Mineral BlendRaw Organic Spirulina, Raw Organic Cracked-Wall Chlorella, Ancient Peat (Trace Minerals)
150 mg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase,  [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU)
60 mg
+

Top Medical Research Studies

9
Zinc reduces migraine symptoms
We conducted a randomized, double-blind, placebo-controlled trial to explore how zinc gluconate affects migraine symptoms in women. Sixty participants, with an average age of 35, were given either 15 mg of zinc per day or a placebo for 12 weeks, allowing us to measure the impact on headache frequency, duration, and intensity.

The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.

Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.

In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
Read More
We explored the impact of zinc on migraine headaches, particularly looking at its effectiveness for those who haven’t found relief from traditional preventive treatments. Our investigation involved four patients suffering from migraine attacks that were resistant to usual prophylactic therapies.

Each of these patients reported a notable improvement in the frequency and severity of their headaches after incorporating zinc supplements into their regimen. This suggests that zinc might serve as a beneficial alternative for those grappling with stubborn migraines.

While our findings are promising, it's crucial to recognize that further research is needed to firmly establish the efficacy of zinc replacement therapy in this context. Nevertheless, zinc administration could offer hope for individuals facing challenges with typical migraine treatment options.
Read More
We explored the connection between zinc intake and migraine through the analysis of cross-sectional data from the National Health and Nutrition Examination Survey conducted between 1999 and 2004. Our aim was to determine if higher dietary zinc could reduce the prevalence of migraines among adults.

In our analysis, we discovered that individuals consuming higher amounts of zinc experienced fewer migraines. Specifically, when comparing participants with the lowest zinc intake to those in higher intake groups, we found significant reductions in migraine occurrence. For example, adjusting for other factors, those in the second and third zinc intake groups had a 27% and 28% lower odds of experiencing migraines, respectively.

We also noted that age plays a role in how zinc intake affects headache prevalence, suggesting that the benefits of dietary zinc may differ depending on age. Interestingly, in adults aged 20 to 50, the relationship between zinc and migraines was not straightforward, indicating a complex interaction.

Overall, this research highlights the potential benefits of increasing zinc in our diets for reducing migraine frequency, and serves as a reminder that dietary choices can have significant health implications.
Read More

Most Useful Reviews

9
Headache-free
Very pleased with fast delivery and high quality. The capsules are a bit large, but easy to swallow. I have started to notice benefits; I was previously worried about frequent headaches, nausea, and fatigue. I've been taking it for 10 days and my headaches have stopped.
Read More
2
Zinc causes headaches
4 people found this helpful
This works as intended, but it's essential to take a copper supplement alongside it since excess zinc can lead to copper deficiency. Unfortunately, I began experiencing headaches with extended use, which is concerning. It's crucial to avoid prolonged use to mitigate this unwanted side effect.
Read More
2
Nausea and headaches
4 people found this helpful
Do not take on an empty stomach! As a holistic health consultant, I prefer high-quality supplements. I added zinc to my routine, but following just one capsule, I felt nauseous and developed a headache. My plans for a pleasant Saturday turned into confusion about this reaction. I shall opt for another brand next time.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
  • All Researches
9
Zinc reduces migraine symptoms
We conducted a randomized, double-blind, placebo-controlled trial to explore how zinc gluconate affects migraine symptoms in women. Sixty participants, with an average age of 35, were given either 15 mg of zinc per day or a placebo for 12 weeks, allowing us to measure the impact on headache frequency, duration, and intensity.

The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.

Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.

In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
Read More
We explored the connection between zinc intake and migraine through the analysis of cross-sectional data from the National Health and Nutrition Examination Survey conducted between 1999 and 2004. Our aim was to determine if higher dietary zinc could reduce the prevalence of migraines among adults.

In our analysis, we discovered that individuals consuming higher amounts of zinc experienced fewer migraines. Specifically, when comparing participants with the lowest zinc intake to those in higher intake groups, we found significant reductions in migraine occurrence. For example, adjusting for other factors, those in the second and third zinc intake groups had a 27% and 28% lower odds of experiencing migraines, respectively.

We also noted that age plays a role in how zinc intake affects headache prevalence, suggesting that the benefits of dietary zinc may differ depending on age. Interestingly, in adults aged 20 to 50, the relationship between zinc and migraines was not straightforward, indicating a complex interaction.

Overall, this research highlights the potential benefits of increasing zinc in our diets for reducing migraine frequency, and serves as a reminder that dietary choices can have significant health implications.
Read More
8
Zinc may help reduce migraines
We explored how dietary zinc intake relates to migraines by analyzing data from the National Health and Nutrition Examination Survey conducted between 1999 and 2004. This cross-sectional study focused on adults who reported experiencing severe headaches or migraines.

Our findings indicated a noteworthy trend: higher intake of dietary zinc was associated with a lower likelihood of having migraines. Specifically, participants with greater zinc consumption—classified into various intake levels—showed a consistent decrease in the odds of experiencing migraine symptoms. For example, those in the highest quintile of zinc intake were 30% less likely to experience migraines compared to those with the lowest intake levels.

This suggests that increasing our zinc intake could be a beneficial strategy for managing migraines. While further research is needed to understand the precise mechanism, the anti-inflammatory and antioxidant properties of zinc may play a crucial role in reducing migraine occurrences.
Read More
8
Zinc chloride may reduce headaches
We evaluated how zinc chloride, used in epipharyngeal abrasive therapy (EAT), might alleviate headaches among patients with long COVID. EAT involves applying zinc chloride to the lining of the epipharynx, where inflammation can linger after COVID-19.

Our study involved 58 patients who received EAT weekly for a month. Before and after the treatment, we measured the intensity of common long COVID symptoms, including fatigue and headaches, using a visual analog scale.

Interestingly, our findings showed that EAT helped reduce inflammation in the epipharynx and significantly improved not only headaches but also fatigue and attention disorders. This suggests that zinc chloride might play a role in easing headache symptoms associated with long COVID.

Overall, we believe this study highlights the potential of EAT as a new treatment avenue for managing long COVID symptoms, particularly headaches, which can often be debilitating for many.
Read More
8
Zinc improves headache symptoms
We observed the use of intravenous calcium and zinc in patients diagnosed with gadolinium deposition disease, with a focus on how this treatment affected their headaches. In our preliminary report involving 25 patients, we noted significant improvements in headache symptoms among those receiving treatment, particularly with a regime of calcium-/zinc-diethylene triamine penta-acetic acid (DTPA).

Patients underwent three courses of treatment, and we measured their urinary gadolinium levels and self-reported symptoms before, during, and after these sessions. The findings revealed a noteworthy increase in Gd content in urine, indicating an effective chelation process, as well as moderate symptomatic relief.

Specifically, 13 patients reported a decrease in headache intensity, along with improvements in other symptoms like brain fog and bone pain. For those on a monthly treatment schedule, there were more significant benefits noted compared to the weekly treatment schedule.

Overall, while there was a transient worsening of symptoms in some patients at first—a phenomenon referred to as a "flare-up"—the outcome suggests that the combination therapy shows promise in alleviating headaches among individuals suffering from this perplexing condition.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 10 Reviews
7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Headache-free
Very pleased with fast delivery and high quality. The capsules are a bit large, but easy to swallow. I have started to notice benefits; I was previously worried about frequent headaches, nausea, and fatigue. I've been taking it for 10 days and my headaches have stopped.
Read More
2
Zinc causes headaches
4 people found this helpful
This works as intended, but it's essential to take a copper supplement alongside it since excess zinc can lead to copper deficiency. Unfortunately, I began experiencing headaches with extended use, which is concerning. It's crucial to avoid prolonged use to mitigate this unwanted side effect.
Read More
2
Nausea and headaches
4 people found this helpful
Do not take on an empty stomach! As a holistic health consultant, I prefer high-quality supplements. I added zinc to my routine, but following just one capsule, I felt nauseous and developed a headache. My plans for a pleasant Saturday turned into confusion about this reaction. I shall opt for another brand next time.
Read More
9
Headache relief
Zinc cool vitamins. They have helped a lot with my headache.
Read More
7.5
Dizziness improved
Good, I have dizziness and headaches due to a lack of zinc in my body. My wife has used a bottle and is feeling better now. I wonder if it’s just a coincidence.
Read More

Frequently Asked Questions

9
Headache-free
Very pleased with fast delivery and high quality. The capsules are a bit large, but easy to swallow. I have started to notice benefits; I was previously worried about frequent headaches, nausea, and fatigue. I've been taking it for 10 days and my headaches have stopped.
7.5
No headaches
Unlike other brands, this zinc supplement did not cause headaches.
2
Notable side effects
6 people found this helpful
The product has a noticeable effect, but it comes with side effects such as headache and buzzing in the ear, based on several experiences with this manufacturer. Yes, and thanks.
9
No side effects
1 people found this helpful
I have tried other zinc tablets which would make me sick within minutes, causing me headaches and nausea. With this brand, I experienced none of that. Although the pills are large, they are easy to swallow.
7.5
Dizziness improved
Good, I have dizziness and headaches due to a lack of zinc in my body. My wife has used a bottle and is feeling better now. I wonder if it’s just a coincidence.
We explored the impact of zinc in managing migraines, which are often debilitating headaches that many people experience. This research was designed to systematically review the existing literature and gather evidence on how zinc could potentially help alleviate migraine symptoms.

Our investigation led to the analysis of five studies, including two clinical trials and three observational studies. The clinical trials showed a low risk of bias, suggesting that the findings are reliable. Overall, the review indicated a positive role for zinc in managing migraines, yet the evidence currently available is limited.

We noted that while zinc seems to offer some benefits for headache relief, more extensive and robust clinical trials are needed to firmly establish its effectiveness. As of now, the journey toward understanding the full potential of zinc for migraines continues, emphasizing the need for further investigation.
9
Zinc reduces migraine symptoms
We conducted a randomized, double-blind, placebo-controlled trial to explore how zinc gluconate affects migraine symptoms in women. Sixty participants, with an average age of 35, were given either 15 mg of zinc per day or a placebo for 12 weeks, allowing us to measure the impact on headache frequency, duration, and intensity.

The results were quite promising; zinc supplementation significantly reduced how often headaches occurred, shortened their duration, and decreased the severity of the migraines reported. Participants in the zinc group experienced notable improvements, as indicated by their responses to the headache severity scale and a disability assessment questionnaire.

Furthermore, we found that zinc also had a positive effect on certain health markers. The serum levels of low-density lipoprotein (LDL), total cholesterol, and high-sensitivity C-reactive protein (hs-CRP) decreased with zinc supplementation. However, we didn’t observe significant changes in triglycerides or high-density lipoprotein (HDL) levels after adjusting for baseline values.

In conclusion, zinc supplementation appears to hold beneficial effects on migraine severity and frequency, offering a potential alternative for those who seek relief from these debilitating headaches.
8
Zinc may help reduce migraines
We explored how dietary zinc intake relates to migraines by analyzing data from the National Health and Nutrition Examination Survey conducted between 1999 and 2004. This cross-sectional study focused on adults who reported experiencing severe headaches or migraines.

Our findings indicated a noteworthy trend: higher intake of dietary zinc was associated with a lower likelihood of having migraines. Specifically, participants with greater zinc consumption—classified into various intake levels—showed a consistent decrease in the odds of experiencing migraine symptoms. For example, those in the highest quintile of zinc intake were 30% less likely to experience migraines compared to those with the lowest intake levels.

This suggests that increasing our zinc intake could be a beneficial strategy for managing migraines. While further research is needed to understand the precise mechanism, the anti-inflammatory and antioxidant properties of zinc may play a crucial role in reducing migraine occurrences.
We explored the impact of zinc on migraine headaches, particularly looking at its effectiveness for those who haven’t found relief from traditional preventive treatments. Our investigation involved four patients suffering from migraine attacks that were resistant to usual prophylactic therapies.

Each of these patients reported a notable improvement in the frequency and severity of their headaches after incorporating zinc supplements into their regimen. This suggests that zinc might serve as a beneficial alternative for those grappling with stubborn migraines.

While our findings are promising, it's crucial to recognize that further research is needed to firmly establish the efficacy of zinc replacement therapy in this context. Nevertheless, zinc administration could offer hope for individuals facing challenges with typical migraine treatment options.
We conducted a randomized clinical trial involving 80 patients to explore the effects of zinc supplementation on migraine headaches. Over the course of eight weeks, participants received either zinc sulfate or a placebo, allowing us to identify any significant differences in migraine characteristics.

Our findings revealed that those taking zinc experienced a notable drop in the frequency of migraine attacks compared to the placebo group. Specifically, the zinc group had an average reduction of 2.55 attacks, while the placebo group saw a minor reduction of just 0.42 attacks.

Furthermore, we observed some reduction in headache severity among those taking zinc, though this effect lost statistical significance when accounting for other factors. It's also important to note that zinc supplementation did not change the duration of the migraine attacks or daily headache impact for the participants.

Overall, our research suggests that zinc supplementation could be beneficial in reducing the frequency of migraine attacks. However, further studies over longer periods and with varying dosages of zinc would be useful to fully understand its potential.

References

  1. Singhal S, Dutta SB, Bansal S, Dutta S, Shah RB. Zinc as An Emerging Therapy in the Management of Migraine: A Systematic Review. Neurol India. 2024;72:934. doi:10.4103/neurol-india.Neurol-India-D-23-00337
  2. Fukazawa R, Ishii R, Higashimoto Y, Hanya M, Shimizu Y, et al. Zinc Administration Favorably Affects Prophylactic Therapy-refractory Migraine Attacks: A Case Series. Intern Med. 2024;63:1631. doi:10.2169/internalmedicine.2111-23
  3. Zheng H, Tian S, Wu L, Zhong X, Liu M, et al. Dietary zinc intake in relation to migraine among adults: a cross sectional study of NHANES 1999-2004. Nutr Neurosci. 2024;27:667. doi:10.1080/1028415X.2023.2243678
  4. Liu H, Wang Q, Dong Z, Yu S. Dietary zinc intake and migraine in adults: a cross-sectional analysis of the National Health and Nutrition Examination Survey 1999-2004. Headache. 2023;63:127. doi:10.1111/head.14431
  5. Imai K, Yamano T, Nishi S, Nishi R, Nishi T, et al. Epipharyngeal Abrasive Therapy (EAT) Has Potential as a Novel Method for Long COVID Treatment. Viruses. 2022;14. doi:10.3390/v14050907
  6. Mazaheri M, Aghdam AM, Heidari M, Zarrin R. Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women. Clin Nutr Res. 2021;10:127. doi:10.7762/cnr.2021.10.2.127
  7. Ahmadi H, Mazloumi-Kiapey SS, Sadeghi O, Nasiri M, Khorvash F, et al. Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial. Nutr J. 2020;19:101. doi:10.1186/s12937-020-00618-9
  8. Semelka RC, Ramalho M, Jay M, Hickey L, Hickey J. Intravenous Calcium-/Zinc-Diethylene Triamine Penta-Acetic Acid in Patients With Presumed Gadolinium Deposition Disease: A Preliminary Report on 25 Patients. Invest Radiol. 2018;53:373. doi:10.1097/RLI.0000000000000453
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