Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
Top Medical Research Studies
9
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Read More
9
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.
Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.
In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.
In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Read More
4
We explored the effectiveness of a short course of oral ranitidine compared to probiotics in treating toddler's diarrhea. In a carefully designed trial, 40 participants were randomly assigned to three groups: those receiving ranitidine, those taking probiotics with vitamin C, and a placebo group.
Our main focus was to see if any of these options could reduce the frequency of stools and improve their consistency after ten days of treatment. While the results showed that oral ranitidine outperformed probiotics in managing toddler's diarrhea, the role of vitamin C was less clear.
It's important to highlight that in this study, the probiotics were combined with vitamin C, making it difficult to isolate its individual effects on diarrhea. Overall, we found that ranitidine was more effective than the probiotics, but we can't confidently say how vitamin C contributed to the outcomes. We recommend further studies to investigate these treatments in more detail.
Our main focus was to see if any of these options could reduce the frequency of stools and improve their consistency after ten days of treatment. While the results showed that oral ranitidine outperformed probiotics in managing toddler's diarrhea, the role of vitamin C was less clear.
It's important to highlight that in this study, the probiotics were combined with vitamin C, making it difficult to isolate its individual effects on diarrhea. Overall, we found that ranitidine was more effective than the probiotics, but we can't confidently say how vitamin C contributed to the outcomes. We recommend further studies to investigate these treatments in more detail.
Read More
Most Useful Reviews
0
Horrible diarrhoea experience
42 people found this helpful
The product works as advertised, but expect diarrhoea. I have a background in fitness and supplementation, and despite my extensive experience, this product has resulted in continuous diarrhoea. Discontinuing stopped the issue, but restarting brings it back. I don’t know whether this is a standard reaction or a fault in the batch, but it’s very frustrating and has never happened to me before.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
- All Researches
9
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Read More
9
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.
Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.
In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.
In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Read More
4
We explored the effectiveness of a short course of oral ranitidine compared to probiotics in treating toddler's diarrhea. In a carefully designed trial, 40 participants were randomly assigned to three groups: those receiving ranitidine, those taking probiotics with vitamin C, and a placebo group.
Our main focus was to see if any of these options could reduce the frequency of stools and improve their consistency after ten days of treatment. While the results showed that oral ranitidine outperformed probiotics in managing toddler's diarrhea, the role of vitamin C was less clear.
It's important to highlight that in this study, the probiotics were combined with vitamin C, making it difficult to isolate its individual effects on diarrhea. Overall, we found that ranitidine was more effective than the probiotics, but we can't confidently say how vitamin C contributed to the outcomes. We recommend further studies to investigate these treatments in more detail.
Our main focus was to see if any of these options could reduce the frequency of stools and improve their consistency after ten days of treatment. While the results showed that oral ranitidine outperformed probiotics in managing toddler's diarrhea, the role of vitamin C was less clear.
It's important to highlight that in this study, the probiotics were combined with vitamin C, making it difficult to isolate its individual effects on diarrhea. Overall, we found that ranitidine was more effective than the probiotics, but we can't confidently say how vitamin C contributed to the outcomes. We recommend further studies to investigate these treatments in more detail.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
0
Horrible diarrhoea experience
42 people found this helpful
The product works as advertised, but expect diarrhoea. I have a background in fitness and supplementation, and despite my extensive experience, this product has resulted in continuous diarrhoea. Discontinuing stopped the issue, but restarting brings it back. I don’t know whether this is a standard reaction or a fault in the batch, but it’s very frustrating and has never happened to me before.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Zakariya MR, Ghasemi E, Hashemzadeh F, Ghorbani GR, Ahmadi F. Does vitamin C supplementation in milk improve growth and health of diarrheic calves?. Prev Vet Med. 2024;224:106122. doi:10.1016/j.prevetmed.2024.106122
- Uwaezuoke SN, Ndu IK, Eneh CI, Anusiem CA, Ayuk AC. A short course of oral ranitidine as a novel treatment for toddler's diarrhea: a parallel-group randomized controlled trial. BMC Pediatr. 2020;20:380. doi:10.1186/s12887-020-02267-7
- Zhang Y, Liu J, Li M, Dong Y, Li Z, et al. Zinc Oxide Administration Relieves the Diarrhea of ETEC K88-Infected Piglets by Reducing Ileal Apoptosis and Maintaining Gut Microbial Balance. Vet Sci. 2025;12. doi:10.3390/vetsci12020115
