Many doctors don't know the importance of iodine unfortunately. I've been using this iodine for 6 months and one concerned symptom that lasted over a year has completely disappeared soon after I started taking this. But I read reviews about the density issue and safety issue of this iodine sold in Amazon, so I contacted Lugol's about it, and here is their response: "Lugol's is made with distilled water. Color may vary depending on storage. We use a tamper evident one piece cap which reveals a ring that separates upon opening and falls to the shoulder of the bottle. All Amazon sellers are known to us. But in general they store in bins and not upright which is what we suggest. We guarantee our product for the life of the bottle." I told them that nothing fell upon opening my bottle, and sent them a photo of my bottle. They said that the ring is still on the cap, and it's possible the ring did not disengage, but usually it separates. * The Amazon sellers of this iodine seem to change quickly. Iodine (I only trust Lugol's so far) is effective for allergy, depression, fatigue, fertility problems, heart arrhythmia, ovarian problems, psoriasis, type 2 diabetes, blood pressure, Fibromyalgia, and the list goes on. Most of us are deficient in iodine. I take this 3 drops in the morning as this can wake you up. I take Selenium supplement and use Himalayan salt (recommend Sherpa Pink Gourmet Himalayan Salt) that will help its effectiveness and also reduces side effects. I didn't have much side effect, except I got very sleepy. Some get headache, skin disorder, fatigue, and if you get those side effects, reduce the amount and if needed gradually increase the amount (1 drop for 1st week, 2 drops for 2nd week). What I understand is that overtaking iodine also causes health issues, but 1-5 drops would be fine, EXCEPT those who has KIDNEY issue. My mom who has kidney issue takes only 1 drop daily (can start from twice a week depending on the person's condition), and her high blood pressure became stable soon after taking this. * Please do this under your sole responsibility. Hope this info is helpful