There are already such wonderfully detailed reviews here that say everything positive that I want to say about Lugol's Solution, so I will let them do the talking. As for myself and my husband, we each take 4 drops in a shot glass of water every morning. If it can help anyone else, here is a little background: After losing 70lb (in a healthy way) to my goal weight a few years ago, and after reaching the age of premenopause a few months ago, I have suffered with freezing cold hands and feet as well as a total intolerance of cold weather. I could barely tolerate having the A/C on! That alone was miserable, but add to it terrible Hot flashes and night sweats, and I just felt like my internal thermostat needed to be replaced. :) I had also been diagnosed last year with a small growth (so far benign) on my thyroid, although my lab levels are normal to date. Well, after only a few months, my icy hands and feet are finally warming up, I no longer need a sweater in 70 - 75 degree temperatures, and with the help of a few other natural supplements, the Hot flashes and night sweats are GONE! I have also noticed a significant improvement in the clarity of my skin and my overall energy level. My husband works around heavy metals and somehow managed to absorb a great deal of Arsenic over the years. Through a 24-hour urine collection, he was diagnosed last year with a body Arsenic level of well over 800, which is more than double the normal level for any human. His doctors began looking into how to purge his system of the Arsenic, as it apparently will not dissipate on its own. In the meantime, I discovered Lugol's Solution and advised him to try it as well. After only a few months, his repeat 24-hour urine collection has revealed that his Arsenic level is normal again! He also has been enjoying a significant improvement in his overall energy level. I should say, too, that I now drink ALLOT of water all day long. . .every time I think about it. I keep a squeeze bottle of water with me at all times, which really increases the amount that I get (kind of like shotgunning. . .you've drunk almost half the bottle in one squeeze before you know it!). Most folks don't realize how much water the human body truly needs on a daily basis. The majority of us don't drink anywhere near enough water to support the proper functioning of our systems. Greatly increasing my water intake has certainly been a revelation to me. The digestive issues, skin complexion issues, blood sugar issues, lack of energy, weight gain and poor immunity that I have struggled with most of my life have been VASTLY improved. . . .Just a little FYI