Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as Thiamine Mononitrate)
25 mg
2,083%
Riboflavin
25 mg
1,923%
Niacin (as Nicotinic Acid)
25 mg NE§
156%
Vitamin B6 (as Pyridoxine HCl [25 mg] and Pyridoxal 5-Phosphate [10 mg])
35 mg
2,059%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
100 mcg
4,167%
Biotin (as d-Biotin)
300 mcg
1,000%
Pantothenic Acid (as Calcium D-Pantothenate)
100 mg
2,000%
Choline (as Choline Bitartrate)
50 mg
9%
Pantethine
25 mg
†
Inositol
50 mg
†
Top Medical Research Studies
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
Most Useful Reviews
9
Hair loss improvement
4 people found this helpful
Very effective. This is my second time ordering this remedy. After surgery, my hair was falling out significantly. After taking it, I quickly noticed a halt to this ‘molting’, which gave me peace of mind.
Read More
7.5
Increased energy
2 people found this helpful
This vitamin B complex has greatly impressed me! I have felt much better throughout the day, and my productivity has surged. My nervous system feels much more stable by day's end, and I appreciate the added energy. Additionally, the niacin doesn't cause flushing, ensuring a top-notch product. I will reorder!
Read More
7.5
Less hair loss
1 people found this helpful
I took these vitamins for about two months, one capsule daily. I've noticed a significant reduction in hair fall; while some hair comes out during washing, it has definitely improved overall. I finished the jar and will be ordering another.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
Biotin deficiency mimics neurological disorders
We explored three cases of biotinidase deficiency (BTD) that were misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD) due to similar symptoms and neuroimaging results. Initially, two patients responded to immune therapy but later relapsed, while one showed no improvement. Interestingly, after timely diagnosis and biotin supplementation, two patients exhibited remarkable recoveries in both motor function and vision. This highlights the critical need for accurate diagnosis, as early treatment of BTD can lead to significant improvements.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Hair loss improvement
4 people found this helpful
Very effective. This is my second time ordering this remedy. After surgery, my hair was falling out significantly. After taking it, I quickly noticed a halt to this ‘molting’, which gave me peace of mind.
Read More
7.5
Increased energy
2 people found this helpful
This vitamin B complex has greatly impressed me! I have felt much better throughout the day, and my productivity has surged. My nervous system feels much more stable by day's end, and I appreciate the added energy. Additionally, the niacin doesn't cause flushing, ensuring a top-notch product. I will reorder!
Read More
7.5
Less hair loss
1 people found this helpful
I took these vitamins for about two months, one capsule daily. I've noticed a significant reduction in hair fall; while some hair comes out during washing, it has definitely improved overall. I finished the jar and will be ordering another.
Read More
7.5
High quality product
I purchased from iHerb and I’m very satisfied with the experience. The product is excellent, and I’ve noticed significant improvement. The quality is superb and prices are reasonable compared to local markets. I appreciated the rapid shipping and great customer service. I highly recommend trying it; I intend to order more in the future!
Read More
0
Negative reaction
6 people found this helpful
Vitamins did not suit me. Although I read reviews claiming these vitamins were excellent for hair loss, I experienced the opposite effect. Instead of feeling energised, I felt lethargic and sleepy after taking them. I consumed them for two weeks at the recommended dosage, but whenever I missed a dose, the drowsiness went away. My hair continued to fall out; perhaps I didn't give them enough time. I won’t be purchasing these again and have opted for different vitamins.
Read More
Frequently Asked Questions
7.5
Less hair loss
1 people found this helpful
I took these vitamins for about two months, one capsule daily. I've noticed a significant reduction in hair fall; while some hair comes out during washing, it has definitely improved overall. I finished the jar and will be ordering another.
7.5
Family benefits
2 people found this helpful
I ordered this for my teenage daughter based on a doctor's recommendation to enhance her intestinal function, bolster her immune system and manage emotional stress. We are starting to notice positive effects, so the whole family has begun taking it as we've heard vitamin B can help reduce panic attacks following our COVID experiences.
6
Minimal improvements
I did not notice significant changes after taking these for two months. I experienced no adverse reactions and there were some improvements, likely indicating no deficiency of vitamin B. My husband and son had no noticeable effects while taking them alongside me. I plan to explore other multivitamins next.
0
Negative reaction
6 people found this helpful
Vitamins did not suit me. Although I read reviews claiming these vitamins were excellent for hair loss, I experienced the opposite effect. Instead of feeling energised, I felt lethargic and sleepy after taking them. I consumed them for two weeks at the recommended dosage, but whenever I missed a dose, the drowsiness went away. My hair continued to fall out; perhaps I didn't give them enough time. I won’t be purchasing these again and have opted for different vitamins.
9
Hair loss improvement
4 people found this helpful
Very effective. This is my second time ordering this remedy. After surgery, my hair was falling out significantly. After taking it, I quickly noticed a halt to this ‘molting’, which gave me peace of mind.
7.5
Increased energy
2 people found this helpful
This vitamin B complex has greatly impressed me! I have felt much better throughout the day, and my productivity has surged. My nervous system feels much more stable by day's end, and I appreciate the added energy. Additionally, the niacin doesn't cause flushing, ensuring a top-notch product. I will reorder!
6
Strengthened immunity
1 people found this helpful
I ordered these for a friend who is thrilled with the capsules. She claims they have significantly boosted her immunity.
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
References
- Jatav VS, Sardana V, Bhushan B, Maheshwari D, Garg S, et al. Correlation of Serum Vitamin B and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure. J Assoc Physicians India. 2025;73:48. doi:10.59556/japi.73.0892
- Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. doi:10.1186/s13256-025-05149-7
- Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. doi:10.1186/s13256-025-05095-4
- Cao AP, Wang YY, Shen YY, Liu YH, Liu JY, et al. Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling. Nutrients. 2024;16. doi:10.3390/nu16162665
- Ali F, Mukhtiar K, Raza M, Ibrahim S. Atypical presentation of biotinidase deficiency: masquerading neuromyelitis optica spectrum disorder. BMJ Case Rep. 2024;17. doi:10.1136/bcr-2023-258703
