Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as Thiamine Mononitrate)
25 mg
2,083%
Riboflavin
25 mg
1,923%
Niacin (as Nicotinic Acid)
25 mg NEĀ§
156%
Vitamin B6 (as Pyridoxine HCl [25 mg] and Pyridoxal 5-Phosphate [10 mg])
35 mg
2,059%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFEā”
170%
Vitamin B12 (as Methylcobalamin)
100 mcg
4,167%
Biotin (as d-Biotin)
300 mcg
1,000%
Pantothenic Acid (as Calcium D-Pantothenate)
100 mg
2,000%
Choline (as Choline Bitartrate)
50 mg
9%
Pantethine
25 mg
ā
Inositol
50 mg
ā
Top Medical Research Studies
9
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
Read More
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
Read More
9
We examined how benfotiamine could help protect hearts from damage due to acute myocardial infarction. In a rat model, heart injury was induced using isoproterenol. Benfotiamine was given both before and after this treatment to see if it could reduce the damage.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
Read More
Most Useful Reviews
8
Restores nervous system
3 people found this helpful
Vitamins B effectively restore the nervous system and induce calmness. Absolutely brilliant. I highly recommend it to those who are faint-hearted.
Read More
7.5
Maintains B vitamins
It is vital to maintain B vitamins within a normal range. This complex is beneficial, containing B1, which is necessary for heart health. I recommend it.
Read More
7.5
Supports heart health
It is a good quality complex of B vitamins. It replenishes energy and supports the heart, adrenal glands, and cerebral vessels.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
- All Researches
9
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
Read More
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
Read More
9
We examined how benfotiamine could help protect hearts from damage due to acute myocardial infarction. In a rat model, heart injury was induced using isoproterenol. Benfotiamine was given both before and after this treatment to see if it could reduce the damage.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
Read More
8
D-pinitol shows potential heart protection
We examined the potential of D-pinitol to protect against heart damage caused by isoproterenol in Swiss albino mice. The mice were divided into eight groups, receiving various doses of D-pinitol alongside isoproterenol or other treatments.
We found that higher doses (50mg and 100mg) of D-pinitol significantly reduced markers of oxidative stress and inflammation, improving heart health. However, the lower dose (25mg) did not show any meaningful benefits. Overall, our findings suggest D-pinitol may have protective effects against heart damage.
We found that higher doses (50mg and 100mg) of D-pinitol significantly reduced markers of oxidative stress and inflammation, improving heart health. However, the lower dose (25mg) did not show any meaningful benefits. Overall, our findings suggest D-pinitol may have protective effects against heart damage.
Read More
7
We investigated how folic acid (FA) could protect against heart injury caused by isoprenaline (ISO) in rats. Over a week, the rats were given FA before being exposed to ISO, which is known to induce heart muscle damage.
The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
8
Restores nervous system
3 people found this helpful
Vitamins B effectively restore the nervous system and induce calmness. Absolutely brilliant. I highly recommend it to those who are faint-hearted.
Read More
7.5
Maintains B vitamins
It is vital to maintain B vitamins within a normal range. This complex is beneficial, containing B1, which is necessary for heart health. I recommend it.
Read More
7.5
Supports heart health
It is a good quality complex of B vitamins. It replenishes energy and supports the heart, adrenal glands, and cerebral vessels.
Read More
0
Irregular heartbeat warning
Read the warnings on this one! The cautions provided are accurate; I would never use this product again. Irregular heartbeats should be added to that list!
Read More
Frequently Asked Questions
8
Restores nervous system
3 people found this helpful
Vitamins B effectively restore the nervous system and induce calmness. Absolutely brilliant. I highly recommend it to those who are faint-hearted.
7.5
Maintains B vitamins
It is vital to maintain B vitamins within a normal range. This complex is beneficial, containing B1, which is necessary for heart health. I recommend it.
7.5
Supports heart health
It is a good quality complex of B vitamins. It replenishes energy and supports the heart, adrenal glands, and cerebral vessels.
0
Irregular heartbeat warning
Read the warnings on this one! The cautions provided are accurate; I would never use this product again. Irregular heartbeats should be added to that list!
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
9
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
7
We explored how dietary intakes of folate, vitamin B6, and vitamin B12 impact heart disease and overall cardiovascular health. Analyzing data from over 115,000 individuals with no prior heart conditions, we found that higher folate consumption was associated with lower risks of cardiovascular events and mortality. Specifically, each increase in folate was linked to a 5% reduction in total cardiovascular incidents and a 10% decline in related deaths. This highlights folate's potential role in preventing heart issues rather than confirming benefits from other B vitamins in this context.
References
- Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413
- Sobot T, Bajic Z, Skrbic R, Uletilovic S, Mandic-Kovacevic N, et al. Effect of folic acid on isoprenaline-induced myocardial injury in rats. Physiol Int. 2024;111:80. doi:10.1556/2060.2023.00291
- Tannous C, Ghali R, Karoui A, Habeichi NJ, Amin G, et al. Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction. Cardiovasc Drugs Ther. 2024;38:1385. doi:10.1007/s10557-023-07525-1
- Zhang B, Dong H, Xu Y, Xu D, Sun H, et al. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort. Eur J Clin Nutr. 2023;77:299. doi:10.1038/s41430-022-01206-2
- Khan A, Iqubal A, Wasim M, Syed MA, Haque SE. D-pinitol attenuates isoproterenol-induced myocardial infarction by alleviating cardiac inflammation, oxidative stress and ultrastructural changes in Swiss albino mice. Clin Exp Pharmacol Physiol. 2022;49:1232. doi:10.1111/1440-1681.13703
- Evens L, Beliƫn H, D'Haese S, Haesen S, Verboven M, et al. Combinational Therapy of Cardiac Atrial Appendage Stem Cells and Pyridoxamine: The Road to Cardiac Repair?. Int J Mol Sci. 2021;22. doi:10.3390/ijms22179266
- Ahmed LA, Hassan OF, Galal O, Mansour DF, El-Khatib A. Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, inĀ isoproterenol-induced myocardial infarction in rats. PLoS One. 2020;15:e0232413. doi:10.1371/journal.pone.0232413
