5/30/2025
Last update
5/30/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as Thiamine Mononitrate)
25 mg
2,083%
Riboflavin
25 mg
1,923%
Niacin (as Nicotinic Acid)
25 mg NE§
156%
Vitamin B6 (as Pyridoxine HCl [25 mg] and Pyridoxal 5-Phosphate [10 mg])
35 mg
2,059%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
100 mcg
4,167%
Biotin (as d-Biotin)
300 mcg
1,000%
Pantothenic Acid (as Calcium D-Pantothenate)
100 mg
2,000%
Choline (as Choline Bitartrate)
50 mg
9%
Pantethine
25 mg
â€
Inositol
50 mg
â€
Top Medical Research Studies
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
Read More
5
Limited evidence for vitamin B effectiveness
We explored various treatments for leg cramps during pregnancy, including vitamin B complex. In our findings, oral vitamin B appeared to reduce the frequency and intensity of leg cramps in a small study involving 42 women.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
Read More
Most Useful Reviews
9
Nightly cramps gone
11 people found this helpful
I liked the B complex. After taking it for a month, my nightly cramps have completely disappeared. I will definitely order more.
Read More
9
Legs regenerated well
2 people found this helpful
I've been taking this for a month as directed, and I noticed results by mid-month. The skin on my legs has improved significantly, and the dryness in other areas has also disappeared.
Read More
7.5
Cramps have vanished
This is my favourite complex! It’s balanced and effective! My parents and I have been taking it together, and muscle cramps have vanished. Additionally, my hair and skin look better, and I feel less stressed!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.3
- All Researches
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
Read More
5
Limited evidence for vitamin B effectiveness
We explored various treatments for leg cramps during pregnancy, including vitamin B complex. In our findings, oral vitamin B appeared to reduce the frequency and intensity of leg cramps in a small study involving 42 women.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Nightly cramps gone
11 people found this helpful
I liked the B complex. After taking it for a month, my nightly cramps have completely disappeared. I will definitely order more.
Read More
9
Legs regenerated well
2 people found this helpful
I've been taking this for a month as directed, and I noticed results by mid-month. The skin on my legs has improved significantly, and the dryness in other areas has also disappeared.
Read More
7.5
Cramps have vanished
This is my favourite complex! It’s balanced and effective! My parents and I have been taking it together, and muscle cramps have vanished. Additionally, my hair and skin look better, and I feel less stressed!
Read More
Frequently Asked Questions
9
Nightly cramps gone
11 people found this helpful
I liked the B complex. After taking it for a month, my nightly cramps have completely disappeared. I will definitely order more.
9
Legs regenerated well
2 people found this helpful
I've been taking this for a month as directed, and I noticed results by mid-month. The skin on my legs has improved significantly, and the dryness in other areas has also disappeared.
7.5
Cramps have vanished
This is my favourite complex! It’s balanced and effective! My parents and I have been taking it together, and muscle cramps have vanished. Additionally, my hair and skin look better, and I feel less stressed!
5
Limited evidence for vitamin B effectiveness
We explored various treatments for leg cramps during pregnancy, including vitamin B complex. In our findings, oral vitamin B appeared to reduce the frequency and intensity of leg cramps in a small study involving 42 women.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
References
- Luo L, Zhou K, Zhang J, Xu L, Yin W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2020;12:CD010655. 10.1002/14651858.CD010655.pub3
- Chan P, Huang TY, Chen YJ, Huang WP, Liu YC. Randomized, double-blind, placebo-controlled study of the safety and efficacy of vitamin B complex in the treatment of nocturnal leg cramps in elderly patients with hypertension. J Clin Pharmacol. 1998;38:1151.
