Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Good
Based on 10 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as Thiamine Mononitrate)
25 mg
2,083%
Riboflavin 
25 mg
1,923%
Niacin (as Nicotinic Acid)
25 mg NE§
156%
Vitamin B6 (as Pyridoxine HCl [25 mg] and Pyridoxal 5-Phosphate [10 mg])
35 mg
2,059%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
100 mcg
4,167%
Biotin (as d-Biotin)
300 mcg
1,000%
Pantothenic Acid (as Calcium D-Pantothenate)
100 mg
2,000%
Choline (as Choline Bitartrate)
50 mg
9%
Pantethine
25 mg
Inositol
50 mg

Top Medical Research Studies

9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.

Most Useful Reviews

9
No nausea
5 people found this helpful
It’s optimal for the price-quality. I have taken this complex several times. The plus side is that the capsules do not cause nausea. They contain vitamins in a well-digestible form, and the price is low. However, I would prefer a larger quantity of some vitamins.
9
No nausea
1 people found this helpful
Truly low-odour and causes minimal stomach upset. This is the first B product I’ve tried that does not induce slight stomach nausea or gagging during swallowing. I am sticking with this one!
0
Causes dizziness
1 people found this helpful
Not satisfied. Very strong, causes dizziness, clash and nausea.

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
  • All Researches
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No nausea
5 people found this helpful
It’s optimal for the price-quality. I have taken this complex several times. The plus side is that the capsules do not cause nausea. They contain vitamins in a well-digestible form, and the price is low. However, I would prefer a larger quantity of some vitamins.
9
No nausea
1 people found this helpful
Truly low-odour and causes minimal stomach upset. This is the first B product I’ve tried that does not induce slight stomach nausea or gagging during swallowing. I am sticking with this one!
0
Causes dizziness
1 people found this helpful
Not satisfied. Very strong, causes dizziness, clash and nausea.
10
No side effects
The content seems to be the best. I purchased this product and am quite satisfied with its size and capacity. There are no side effects like nausea at all.
9
No nausea
There is no taste, and my children can take it without experiencing nausea or vomiting after meals.

Frequently Asked Questions

9
More energy
The capsule size is large! It lasts six months, with an optimal composition for those who train. I’ve been taking it for 10 days now and have noticed a significant increase in energy, my headaches have ceased, and I have a better mood throughout the day. I recommend it for those interested in fitness.
7.5
More energy
Good composition, fast delivery, and excellent packaging. I take one capsule daily with meals. Before starting, I often faced headaches, nausea, and fatigue. After taking it for 10 days, I feel energetic, my headaches have stopped, and my mood is consistently good. I recommend it for anyone into sports or fitness.
9
No nausea
1 people found this helpful
Truly low-odour and causes minimal stomach upset. This is the first B product I’ve tried that does not induce slight stomach nausea or gagging during swallowing. I am sticking with this one!
9
No nausea
There is no taste, and my children can take it without experiencing nausea or vomiting after meals.
4
Nausea complaints
1 people found this helpful
Be careful with niacin acid! The vitamin composition is good, but B3 is in the form of niacin acid, which causes nausea, red eyes, and poor health for my dad. It would be preferable if B3 were in the no-flush form. The nutriologist mentioned that B3 complexes are unsuitable for him due to high homocysteine levels.
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.

References

  1. Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. doi:10.1097/ALN.0000000000005354
  2. Hayashi E, Matuura T, Takano J, Morofushi K, Toriizuka K, et al. Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi. Palliat Support Care. 2024;22:1511. doi:10.1017/S1478951524000415
  3. Saz-Leal P, Zamorano-Domínguez L, Frías J, Guerra P, Saura-Valls M, et al. Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy. Drugs R D. 2023;23:185. doi:10.1007/s40268-023-00425-7
  4. Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2023;308:1075. doi:10.1007/s00404-023-06925-w
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