SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.6
USERS' SCORE
Good
Based on 4 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Bromelain
500 mg (1,000 GDU‡)

Top Medical Research Studies

9
Bromelain aids in allergy diagnosis
Cross-Reactive Carbohydrate Determinant in , and Venoms: Identification of Allergic Sensitization and Cross-Reactivity.
Significant for allergy testing
We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.

Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.

Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Read More
8
Bromelain reduces allergic airway inflammation
Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.
Highly relevant to allergy treatment
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.

Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.

However, further research is needed to confirm these effects in human subjects.
Read More
9.5
Plant vaccines show no allergy risk
Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines.
Significant relevance to allergies
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.

While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More

Most Useful Reviews

9.5
Symptom relief
For my seasonal allergies, bromelain works exceedingly well; it effectively alleviates all symptoms. I suffered from a dreadful runny nose and itchy eyes that hindered my ability to work, but bromelain, along with quercetin, has been extremely beneficial. All symptoms have vanished, although I still experience minor nasal congestion, which is manageable. I highly recommend it.
Read More
9.5
Fights seasonal allergies
Excellent bromelain that works effectively against seasonal allergies; I appreciate the quality of this brand. I also take it with quercetin.
Read More
8.8
Improvement seen
I purchased this to supplement alongside nettle for alleviating seasonal allergies. I have noticed benefits thus far. It appears to be of top-notch quality, and I would buy it again.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.6
  • All Researches
9.5
Plant vaccines show no allergy risk
Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines.
Significant relevance to allergies
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.

While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More
9
Bromelain aids in allergy diagnosis
Cross-Reactive Carbohydrate Determinant in , and Venoms: Identification of Allergic Sensitization and Cross-Reactivity.
Significant for allergy testing
We examined how bromelain, a pineapple extract, helps in identifying allergies to Hymenoptera venom. By analyzing serum from 51 patients, we found that many presented cross-reactive IgE due to a carbohydrate called CCD.

Bromelain played a key role in revealing these cross-reactions, as seen in cases where it significantly reduced reactivity to venom allergens. However, it didn't change the reactivity to specific allergenic peptide epitopes.

Our findings suggest that bromelain could be a valuable tool in better diagnosing and differentiating true allergies from cross-reactive responses.
Read More
8
Bromelain reduces allergic airway inflammation
Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.
Highly relevant to allergy treatment
We explored how bromelain, a natural extract from pineapples, influences allergic airway disease in a mouse model. Mice were sensitized and treated with bromelain or saline over several days.

Results showed that bromelain significantly reduced inflammation markers and altered key immune cell populations. Consequently, we see potential in bromelain for the management of allergies, asthma, and similar conditions in humans.

However, further research is needed to confirm these effects in human subjects.
Read More
8
Bromelain aids sinusitis recovery
Therapeutic use, efficiency and safety of the proteolytic pineapple enzyme Bromelain-POS in children with acute sinusitis in Germany.
Relevant for pediatric treatment
We examined how bromelain, an enzyme derived from pineapple, affects children under 11 with acute sinusitis. In our study involving 116 patients across Germany, we compared those treated with bromelain alone, standard treatments, and a mix of both.

The results revealed that the bromelain group had the quickest recovery, with symptoms lasting about 6.66 days. Interestingly, only one patient had a mild allergic reaction, which was self-limiting. Overall, bromelain appears to provide a beneficial treatment option for young children suffering from acute sinusitis.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Symptom relief
For my seasonal allergies, bromelain works exceedingly well; it effectively alleviates all symptoms. I suffered from a dreadful runny nose and itchy eyes that hindered my ability to work, but bromelain, along with quercetin, has been extremely beneficial. All symptoms have vanished, although I still experience minor nasal congestion, which is manageable. I highly recommend it.
Read More
9.5
Fights seasonal allergies
Excellent bromelain that works effectively against seasonal allergies; I appreciate the quality of this brand. I also take it with quercetin.
8.8
Improvement seen
I purchased this to supplement alongside nettle for alleviating seasonal allergies. I have noticed benefits thus far. It appears to be of top-notch quality, and I would buy it again.
8.8
Versatile product
Versatile and very effective for my joints and allergies; quality product.

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