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SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 1 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Lactoferrin (as Apolactoferrin)
250 mg
†
Top Medical Research Studies
8
Lactoferrin combats oral candidiasis
Lactoferrin as a potential therapeutic for the treatment of Candida-associated denture stomatitis.
Highly relevant antifungal study
We investigated how lactoferrin, a multifunctional protein found in saliva, impacts the treatment of candidiasis, particularly in the context of denture stomatitis caused by Candida. This condition is often challenging to manage due to lingering factors and the potential for repeated occurrences.
Our findings highlight that lactoferrin is believed to be a first line of defense against microbial threats on mucosal surfaces. We discovered that lactoferrin and its derivatives have the potential to tackle a wide range of Candida species effectively.
Given the rise in drug resistance among fungi, the search for new treatments is crucial. Lactoferrin presents an interesting option, either on its own or alongside established medications, for improving outcomes in oral candidiasis treatment. This review sheds light on the current understanding and efficacy of lactoferrin's antifungal properties in dealing with oral candidiasis.
Our findings highlight that lactoferrin is believed to be a first line of defense against microbial threats on mucosal surfaces. We discovered that lactoferrin and its derivatives have the potential to tackle a wide range of Candida species effectively.
Given the rise in drug resistance among fungi, the search for new treatments is crucial. Lactoferrin presents an interesting option, either on its own or alongside established medications, for improving outcomes in oral candidiasis treatment. This review sheds light on the current understanding and efficacy of lactoferrin's antifungal properties in dealing with oral candidiasis.
Read More
8
Lactoferrin reduces Candida pathogenicity
Impact of Brief Exposure to Lysozyme and Lactoferrin on Pathogenic Attributes of Oral Candida.
Direct investigation of lactoferrin effects
We investigated the impact of lactoferrin on oral Candida species, specifically focusing on how it affects their ability to cause infections. To do this, we treated 20 isolates of Candida albicans and Candida dubliniensis with lactoferrin for one hour, and then assessed various pathogenic characteristics after a 48-hour incubation period.
Our study looked at important factors like the adherence of these Candida isolates to buccal epithelial cells and denture surfaces, the formation of germ tubes, cell surface hydrophobicity, and the production of haemolysin. We found that even brief exposure to lactoferrin significantly reduced these pathogenic traits in vitro.
These findings suggest that lactoferrin could have a lasting antifungal effect by diminishing the ability of these yeasts to adhere and produce harmful substances. Given the growing resistance to traditional antifungal medications, these results open up exciting avenues for developing alternative therapies for managing oral candidosis.
However, further research is needed to fully understand how lactoferrin works and its potential for use in clinical settings. We see this study as a stepping stone toward creating new topical antifungal treatments that could be more effective against resistant strains.
Our study looked at important factors like the adherence of these Candida isolates to buccal epithelial cells and denture surfaces, the formation of germ tubes, cell surface hydrophobicity, and the production of haemolysin. We found that even brief exposure to lactoferrin significantly reduced these pathogenic traits in vitro.
These findings suggest that lactoferrin could have a lasting antifungal effect by diminishing the ability of these yeasts to adhere and produce harmful substances. Given the growing resistance to traditional antifungal medications, these results open up exciting avenues for developing alternative therapies for managing oral candidosis.
However, further research is needed to fully understand how lactoferrin works and its potential for use in clinical settings. We see this study as a stepping stone toward creating new topical antifungal treatments that could be more effective against resistant strains.
Read More
4
Salivary proteins and candidiasis
Salivary proteins modulate Candida albicans virulence and may prevent oropharingeal candidiasis.
Lactoferrin's effects unclear
We delved into how two proteins found in saliva, histatin 5 and lactoferrin, influence the survival and harmfulness of Candida albicans, the primary cause of oral thrush. Our focus was on a specific strain of C. albicans that is resistant to fluconazole, a common antifungal medication.
We discovered that while both proteins contributed to reducing the yeast's cell viability, lactoferrin didn't significantly alter its effectiveness in the same way as histatin 5. In fact, histatin 5 was responsible for decreasing the presence of certain proteins on the surface of C. albicans, showcasing a stronger impact overall.
Although lactoferrin showed some degree of antifungal activity, it lacked the remarkable capacity of histatin 5. Therefore, we believe that maintaining appropriate levels of these salivary proteins could be crucial in preventing oropharyngeal candidiasis. Their administration might serve as a potential therapy, especially for cases resistant to traditional treatments, despite lactoferrin's less clear impact.
We discovered that while both proteins contributed to reducing the yeast's cell viability, lactoferrin didn't significantly alter its effectiveness in the same way as histatin 5. In fact, histatin 5 was responsible for decreasing the presence of certain proteins on the surface of C. albicans, showcasing a stronger impact overall.
Although lactoferrin showed some degree of antifungal activity, it lacked the remarkable capacity of histatin 5. Therefore, we believe that maintaining appropriate levels of these salivary proteins could be crucial in preventing oropharyngeal candidiasis. Their administration might serve as a potential therapy, especially for cases resistant to traditional treatments, despite lactoferrin's less clear impact.
Read More
Most Useful Reviews
3.5
No improvement
I tried this product for my candidiasis (systemic yeast infection) but received no results and will discontinue use.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
8
Lactoferrin combats oral candidiasis
Lactoferrin as a potential therapeutic for the treatment of Candida-associated denture stomatitis.
Highly relevant antifungal study
We investigated how lactoferrin, a multifunctional protein found in saliva, impacts the treatment of candidiasis, particularly in the context of denture stomatitis caused by Candida. This condition is often challenging to manage due to lingering factors and the potential for repeated occurrences.
Our findings highlight that lactoferrin is believed to be a first line of defense against microbial threats on mucosal surfaces. We discovered that lactoferrin and its derivatives have the potential to tackle a wide range of Candida species effectively.
Given the rise in drug resistance among fungi, the search for new treatments is crucial. Lactoferrin presents an interesting option, either on its own or alongside established medications, for improving outcomes in oral candidiasis treatment. This review sheds light on the current understanding and efficacy of lactoferrin's antifungal properties in dealing with oral candidiasis.
Our findings highlight that lactoferrin is believed to be a first line of defense against microbial threats on mucosal surfaces. We discovered that lactoferrin and its derivatives have the potential to tackle a wide range of Candida species effectively.
Given the rise in drug resistance among fungi, the search for new treatments is crucial. Lactoferrin presents an interesting option, either on its own or alongside established medications, for improving outcomes in oral candidiasis treatment. This review sheds light on the current understanding and efficacy of lactoferrin's antifungal properties in dealing with oral candidiasis.
Read More
8
Lactoferrin reduces Candida pathogenicity
Impact of Brief Exposure to Lysozyme and Lactoferrin on Pathogenic Attributes of Oral Candida.
Direct investigation of lactoferrin effects
We investigated the impact of lactoferrin on oral Candida species, specifically focusing on how it affects their ability to cause infections. To do this, we treated 20 isolates of Candida albicans and Candida dubliniensis with lactoferrin for one hour, and then assessed various pathogenic characteristics after a 48-hour incubation period.
Our study looked at important factors like the adherence of these Candida isolates to buccal epithelial cells and denture surfaces, the formation of germ tubes, cell surface hydrophobicity, and the production of haemolysin. We found that even brief exposure to lactoferrin significantly reduced these pathogenic traits in vitro.
These findings suggest that lactoferrin could have a lasting antifungal effect by diminishing the ability of these yeasts to adhere and produce harmful substances. Given the growing resistance to traditional antifungal medications, these results open up exciting avenues for developing alternative therapies for managing oral candidosis.
However, further research is needed to fully understand how lactoferrin works and its potential for use in clinical settings. We see this study as a stepping stone toward creating new topical antifungal treatments that could be more effective against resistant strains.
Our study looked at important factors like the adherence of these Candida isolates to buccal epithelial cells and denture surfaces, the formation of germ tubes, cell surface hydrophobicity, and the production of haemolysin. We found that even brief exposure to lactoferrin significantly reduced these pathogenic traits in vitro.
These findings suggest that lactoferrin could have a lasting antifungal effect by diminishing the ability of these yeasts to adhere and produce harmful substances. Given the growing resistance to traditional antifungal medications, these results open up exciting avenues for developing alternative therapies for managing oral candidosis.
However, further research is needed to fully understand how lactoferrin works and its potential for use in clinical settings. We see this study as a stepping stone toward creating new topical antifungal treatments that could be more effective against resistant strains.
Read More
4
Salivary proteins and candidiasis
Salivary proteins modulate Candida albicans virulence and may prevent oropharingeal candidiasis.
Lactoferrin's effects unclear
We delved into how two proteins found in saliva, histatin 5 and lactoferrin, influence the survival and harmfulness of Candida albicans, the primary cause of oral thrush. Our focus was on a specific strain of C. albicans that is resistant to fluconazole, a common antifungal medication.
We discovered that while both proteins contributed to reducing the yeast's cell viability, lactoferrin didn't significantly alter its effectiveness in the same way as histatin 5. In fact, histatin 5 was responsible for decreasing the presence of certain proteins on the surface of C. albicans, showcasing a stronger impact overall.
Although lactoferrin showed some degree of antifungal activity, it lacked the remarkable capacity of histatin 5. Therefore, we believe that maintaining appropriate levels of these salivary proteins could be crucial in preventing oropharyngeal candidiasis. Their administration might serve as a potential therapy, especially for cases resistant to traditional treatments, despite lactoferrin's less clear impact.
We discovered that while both proteins contributed to reducing the yeast's cell viability, lactoferrin didn't significantly alter its effectiveness in the same way as histatin 5. In fact, histatin 5 was responsible for decreasing the presence of certain proteins on the surface of C. albicans, showcasing a stronger impact overall.
Although lactoferrin showed some degree of antifungal activity, it lacked the remarkable capacity of histatin 5. Therefore, we believe that maintaining appropriate levels of these salivary proteins could be crucial in preventing oropharyngeal candidiasis. Their administration might serve as a potential therapy, especially for cases resistant to traditional treatments, despite lactoferrin's less clear impact.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Reviews
8
3.5
No improvement
I tried this product for my candidiasis (systemic yeast infection) but received no results and will discontinue use.
