Medical Researches
Possibly Effective
Based on 2 Researches
Lactoferrin alleviates PEDV diarrheaLactoferrin exhibits PEDV antiviral activity by interfering with spike-heparan sulfate proteoglycans binding and activating mucosal immune response.
Relevant to PEDV diarrhea research
This study aimed to understand how lactoferrin can help reduce the impact of Porcine Epidemic Diarrhea Virus (PEDV), which causes severe diarrhea and high mortality in neonatal piglets. By investigating both laboratory and animal models, we observed that lactoferrin possesses antiviral properties that can inhibit PEDV replication.
Specifically, we found that lactoferrin may work by blocking the virus from binding to specific proteins on the surface of piglet cells. Additionally, our findings indicated that lactoferrin can enhance the immune response in piglets, boosting their intestinal defenses against the virus.
Overall, these results suggest that incorporating lactoferrin into the diets of pregnant sows could provide a layer of protection for their piglets against severe diarrhea caused by PEDV. By improving both direct antiviral action and immune function, lactoferrin represents a promising avenue for minimizing the devastation of this viral infection in young pigs.
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We conducted a comprehensive review and meta-analysis to understand how lactoferrin (LF) supplementation affects diarrhea in children. This involved examining a number of randomized controlled trials involving participants under 18 years old.
From our analysis, which sifted through an impressive 1,594 citations, we identified 25 studies that met our criteria. Notably, out of these, 14 studies focused specifically on diarrhea. Our findings indicated that LF supplementation was linked to fewer children experiencing diarrhea compared to those receiving a placebo.
Specifically, the odds of having diarrhea were reduced (with an odds ratio of 0.56) when children were given LF compared to those who weren't. This suggests that lactoferrin could be helpful in reducing the incidence of diarrhea in the pediatric population. However, it's important to note that while the results are promising, further refinement in trial design is necessary to fully understand LF's potential as a public health tool.
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User Reviews
Medium or Average
Based on 17 Reviews
This is a supplement I frequently buy. Although the price has increased, I continue taking it for my intestinal health. Unless I consume a lot of fatty foods or desserts, I no longer notice any stool odour. I believe this has also eliminated body odour, particularly noticeable in summer. I even give a small amount to my dog, and he too has benefited from reduced stool odour. However, caution is advised when administering it to pets.
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This product is excellent. The capsules are easy to swallow. I took it to increase my iron levels because a prior single iron dose caused diarrhoea. Thankfully, I've seen no diarrhoea since starting this supplement and my iron levels improved. I highly recommend it; lactoferrin is a unique product that could soon replace antibiotics.
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I took lactoferrin after a course of berberine on my doctor's advice to enhance bowel function. The results were positive; my overall health improved and my bowel movements became more regular, resolving my previous issues with constipation and diarrhoea. I plan to reorder it occasionally. Additionally, I've noticed a pleasant side effect: my skin has cleared up and the rashes have diminished.
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I purchased this for my cat, who struggled with dry food. Concerned about the limited lactoferrin content in other products, I found this supplement. After starting with a quarter of a capsule, I've gradually increased it. Now, nine months later, my cat eats more normally without gastrointestinal issues like diarrhoea. There are still some red spots on his gums, but he seems to be doing well.
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As a nutritional supplement for cats, I've noticed that administering small amounts helps prevent diarrhoea. It seems to aid their immunity effectively.