So I've had a rough year this year and because of all the illnesses and I suspect the use of an antibiotic, my immune system took a dive. Particularly my RBC and WBC were affected. They were so low I was recommended to a hematologist. Before I got the appointment- which took forever, I came across some posts about this supplement. They were all very positive and so are many of the reviews. I got a UTI and while I was on IV antibiotics I was hit with a virus that later caused skin eruptions and then later I came up with another positive urine culture. That time around I opted not to do antibiotics but I was so ill my GP wanted blood work which revealed the low counts. She said you're not iron deficient but it's like you're losing blood. Then my OB took blood work and it revealed the same thing a couple of weeks later and both doctors agree I needed hematology. Hematology took blood and the first test revealed there had been no change and all of the blood tests happened within about a 3 month span. So basically I was stable. I had been taking some vitamin Eand a couple of other immune supporting supps for about a months before the last test. The hematologist put me on polysaccharide iron- which had great reviews, but I had been studying natural healing and many sources said to stay away from iron pills because infection feed on them - I was fighting a couple. What was suggested is lactoferrin because it is supposed to make shire that iron is used by the body without being used by pathogens. I started with 500 mg. I noticed nothing. I was still extremely exhausted and one resistant infection persisted . I was hoping for it to kill Proteus miribalis which had been the source of my UTI among other things. Imagine i took it I noticed nothing at all. Gradually I felt my strength and appetite returning but I never attributed it to lactoferrin. I was also taking Perfect Desicated Liver instead of iron because again among natural healing circles it was better than iron and it you look at the reviews people boast about miracles on this stuff. So I only took very little polysaccharide iron and then none at all just the Perfect and Lactoferrin. Well my next visit indicated my iron levels had dropped-- now they were not even stable like they were when I basically only took Vitamin E and maybe some vitamin C. Of course I was very frustrated and I felt nearly defeated. I stopped lactoferrin and Perfect altogether because I wondered if they had actually contributed to the drop. Fast forward about two weeks later: I had to take a steroid for an ear issue but I noticed that I felt very different. Like my body was missing something. My bladder started to feel weird, but I wanted to complete the steroid without any supplements. And I did but as soon as I could I started with 500 mg lactoferrin. I noticed nothing really... But then I think the r resistant infection started to rage after the steroids and 500mg wasn't going to do it. So after a minute I used 1509 mg the way I had previously been doing and I began to feel slight relief. So while I can't put my finger on it- I think lactoferrin helps me but it didn't help with my iron counts. I think orbit some way helps my bladder health-- possibly because of its ability to inhibit certain pathogens. And it helps at 1500 mg per day- nothing less- which is pricey but I think it's helping. It's a hard decision to choose if I want my RBC to drop because of a supplement because it helps my bladder. Again, I'm not sure if that's what caused the drop- but it is very odd, because I was super sick while it was stable and then with the lactoferrin I didn't feel as sick but the numbers don't lie... But if anyone has ever had a resistant infection and a bladder infection then you understand the toss up here. Bladder issues are the worse. Now I'm getting IV iron and taking the lactoferrin so my next labs are in a month and if it drops again I would be comfortable saying it's the lactoferrin but if not then I'll update and increase ton4or 5 stars