We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Reduced mental fatigue
Excellent! I have experienced decreased mental fatigue and forgetfulness.
Read More
7.5
Effective magnesium for fatigue
16 people found this helpful
Symptoms of adrenal fatigue have calmed significantly since I started using Vitamin B and C alongside magnesium. Initially, I used a product from SOLGAR, and although it took about three months to see improvement, my symptoms did subside. After SOLGAR's products were no longer available, I faced challenges until I discovered magnesium. It's proven to be the most effective, whereas other remedies for adrenal fatigue fell short. Despite the importance of vitamins B and C, I believe the inclusion of magnesium is crucial in alleviating chronic fatigue syndrome.
Read More
7.5
Best form for chronic migraines
Magnesium threonate is the best form I've found for managing my severe chronic migraines. Even though it's pricier than other types, the quality and effectiveness make it worthwhile.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Reduced mental fatigue
Excellent! I have experienced decreased mental fatigue and forgetfulness.
Read More
7.5
Effective magnesium for fatigue
16 people found this helpful
Symptoms of adrenal fatigue have calmed significantly since I started using Vitamin B and C alongside magnesium. Initially, I used a product from SOLGAR, and although it took about three months to see improvement, my symptoms did subside. After SOLGAR's products were no longer available, I faced challenges until I discovered magnesium. It's proven to be the most effective, whereas other remedies for adrenal fatigue fell short. Despite the importance of vitamins B and C, I believe the inclusion of magnesium is crucial in alleviating chronic fatigue syndrome.
Read More
7.5
Best form for chronic migraines
Magnesium threonate is the best form I've found for managing my severe chronic migraines. Even though it's pricier than other types, the quality and effectiveness make it worthwhile.
Read More
7.5
Effective during stress
I liked that there are several types of magnesium in the composition. I took it during a stressful period and noted that it was extremely effective even in combating fatigue.
Read More
Frequently Asked Questions
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, the timeframe for experiencing results from supplements for Chronic Fatigue Syndrome can vary significantly. One user reported that it took about three months to see noticeable improvements in symptoms when incorporating Vitamin B and C alongside magnesium into their routine Read Review. This suggests that while some individuals may start feeling better within a few weeks, others might require a longer period to notice tangible benefits.
Additionally, other users have highlighted improvements in mental fatigue and overall well-being shortly after beginning their supplementation, although specific timelines weren't provided Read Review. It's important to note that individual responses can vary widely, which could be influenced by factors such as the specific supplements used, dosage, and an individual’s unique health circumstances. Therefore, patience and consistency with the supplement regimen could play a significant role in seeing effective results.
Magnesium supplementation has emerged as a potential aid for individuals battling Chronic Fatigue Syndrome (CFS), with various studies exploring its effectiveness. A systematic review of randomized controlled trials identified magnesium as a treatment option with some positive effects, although it highlighted that the overall effectiveness of therapies for CFS remains limited. The researchers noted that more robust studies are necessary to confirm magnesium's benefits due to small sample sizes and biases in existing studies [1].
Furthermore, specific trials found that patients with CFS often exhibit lower magnesium levels compared to healthy individuals. In one randomized, double-blind trial involving 32 participants, those who received magnesium sulfate treatment reported notable enhancements in energy, emotional wellbeing, and even pain relief when compared to the placebo group [5]. Another case study highlighted a 29-year-old woman whose fatigue significantly diminished after she received intravenous magnesium sulfate treatment [3]. However, while these findings elucidate magnesium's potential benefits, it’s essential to approach its use cautiously, as it is not a definitive solution for CFS, and further research is warranted to establish its role in treatment plans [4].
Users have reported a variety of improvements in their symptoms associated with chronic fatigue and mental strain after incorporating specific supplements, particularly magnesium and vitamins B and C. One user shared their experience of significant reductions in mental fatigue and forgetfulness, contributing to their overall cognitive clarity and functioning Read Review. Another mentioned that their symptoms of adrenal fatigue calmed significantly after about three months of consistent supplementation with Vitamin B and C, as well as magnesium, underscoring the importance of magnesium in alleviating chronic fatigue syndrome Read Review.
Additionally, some users noted that different forms of magnesium, such as magnesium threonate, have been particularly effective for managing other related issues like migraines, indicating that the choice of supplement can play a crucial role in symptom management Read Review. Others have emphasized the benefits of various types of magnesium, especially during stressful periods where fatigue can be particularly debilitating Read Review. Overall, while these accounts reflect positive outcomes, individual results can vary based on personal health circumstances and the specific supplementation regimen.
Users have reported positive experiences when combining this supplement with a variety of vitamins, particularly B and C, for managing Chronic Fatigue Syndrome. One user shared that their symptoms of adrenal fatigue improved significantly after consistently using Vitamin B and C alongside magnesium, although it took about three months to notice these benefits Read Review. This suggests that while the combination of these supplements can be beneficial, results may vary, and patience is often required in the journey toward symptom relief.
Additionally, the type of magnesium used appears to have an impact on effectiveness. One reviewer emphasized their success with magnesium threonate, particularly for alleviating severe migraines, indicating that choosing high-quality forms of magnesium can enhance overall symptom management Read Review. Other users noted improvements in fatigue during stressful periods with different magnesium formulations Read Review. These insights point to the potential of combining various supplements for tailored approaches to combating Chronic Fatigue Syndrome.
Users have reported varying experiences with magnesium for treating Chronic Fatigue Syndrome, often highlighting its effectiveness when combined with other vitamins. One user noted a significant decrease in mental fatigue and forgetfulness after starting magnesium supplementation Read Review. Another review indicated that while it took about three months to achieve noticeable improvement, magnesium was crucial in alleviating symptoms associated with adrenal fatigue, making it more effective than other remedies Read Review.
Additionally, for those suffering from migraines alongside chronic fatigue, magnesium threonate was emphasized as the best form due to its quality and effectiveness, despite its higher price point Read Review. Those managing stress and fatigue reported success with formulations containing multiple types of magnesium, further suggesting that versatility in magnesium supplementation could be beneficial for a broader range of symptoms Read Review. However, specific dosages were not detailed in the reviews, leaving the ideal amount for treatment somewhat ambiguous.
7.5
Effective magnesium for fatigue
16 people found this helpful
Symptoms of adrenal fatigue have calmed significantly since I started using Vitamin B and C alongside magnesium. Initially, I used a product from SOLGAR, and although it took about three months to see improvement, my symptoms did subside. After SOLGAR's products were no longer available, I faced challenges until I discovered magnesium. It's proven to be the most effective, whereas other remedies for adrenal fatigue fell short. Despite the importance of vitamins B and C, I believe the inclusion of magnesium is crucial in alleviating chronic fatigue syndrome.
9
Reduced mental fatigue
Excellent! I have experienced decreased mental fatigue and forgetfulness.
7.5
Best form for chronic migraines
Magnesium threonate is the best form I've found for managing my severe chronic migraines. Even though it's pricier than other types, the quality and effectiveness make it worthwhile.
7.5
Effective during stress
I liked that there are several types of magnesium in the composition. I took it during a stressful period and noted that it was extremely effective even in combating fatigue.
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.