Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Moderately Good
Based on 33 Reviews
7.4
Supplement Facts
Serving Size: 3 Capsules
Serving Per Container:  30
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magnesium L-Threonate)
144 mg
34%

Top Medical Research Studies

We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
We examined how various tocolytic drugs delay preterm birth, analyzing data from 122 trials involving nearly 13,700 women.

Our findings suggest that all classes of tocolytics, including magnesium sulfate, are likely effective for delaying birth up to 7 days compared to no treatment.

While these treatments showed promise, they also carried risks of side effects, such as nausea and headaches, particularly with betamimetics and calcium channel blockers. We found no definitive conclusions on their impact on neonatal outcomes, leaving room for further research.
Read More
7
Magnesium's efficacy for headaches
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.

Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.

Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
Read More

Most Useful Reviews

9
Tension eased
13 people found this helpful
I've tried numerous magnesium supplements, but this one is exceptional. It alleviates my tension headaches and migraines, particularly the severe muscle spasms following a brain injury. I've learned that consuming carbonated drinks can exacerbate magnesium issues, leading to agonising muscle spasms. By taking this supplement after such beverages, I can avoid significant discomfort and enjoy its beneficial effects.
Read More
9
Headache relief
11 people found this helpful
The magnesium L-threonate supplement is the most absorbable form in the body. After a month of taking three capsules a day, I've noticed a significant reduction in stress and irritability, and I no longer suffer from headaches. My state of calm is now habitual, and my hair has also improved – they seem stronger and shinier. Although it is an expensive form of magnesium, it is high quality and effective. I highly recommend it!
Read More
10
Body aches gone
9 people found this helpful
This product has greatly improved my situation. Within a week, my usual body aches and headaches from insufficient sleep disappeared. Even while working long hours in cold weather, my cognitive abilities improved remarkably. I recommend starting slowly for better acclimation. Additionally, my hormonal balance has improved this month, making me consider never going without this supplement again.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
  • All Researches
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
Read More
We examined the effects of magnesium treatment on individuals suffering from episodic migraine and tension-type headache, aiming to understand its potential benefits alongside other therapeutic approaches. The study involved 104 participants, who were assessed for anxiety, depression, insomnia, and fatigue before and after receiving various treatments, including magnesium.

Our findings indicated that a significant portion of patients reported anxiety and depression, affecting their headache severity. After treatment, we noticed a marked decrease in headache intensity, along with improvements in anxiety and depressive symptoms. However, the specific impact of magnesium alone couldn’t be isolated in this study, as we looked at it alongside other medications like anxiolytics and antidepressants.

Overall, while magnesium was part of the treatment plan and showed potential benefits, we must acknowledge that its individual effectiveness cannot be clearly determined from our research. It appears to contribute to an overall improvement in managing headaches when combined with other treatments.
Read More
9
Multimodal therapy shows promise
We explored a case involving a 36-year-old woman with endometriosis suffering from frequent headaches and debilitating pain. While traditional medications didn't work for her, she started a new treatment plan that included acupuncture and supplements like magnesium and turmeric.

After this multimodal approach, her headache frequency decreased significantly, along with improvements in her lumbopelvic pain, sleep quality, and overall focus. This case indicates that integrating various alternative therapies can provide significant relief for those with challenging symptoms.
Read More
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.

After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.

Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.

Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
Read More
We examined the idea that Meniere's disease (MD) might actually be a form of migraine rather than just a standalone inner ear issue. Interestingly, we found that while only about 12% of the general population deals with migraines, a staggering 51-60% of those with MD also experience migraine headaches regularly.

Furthermore, we learned that endolymphatic hydrops, a key feature often associated with MD, has also been spotted in people suffering from vestibular migraine. This connection hints that treating migraine might also benefit those with MD. A particularly effective approach we've seen involves changes in diet and lifestyle, along with magnesium and riboflavin supplements, and possibly preventative medication to manage migraine symptoms.

By treating the underlying migraine aspect, we observed that patients with MD can find relief and improvement. This indicates that MD might best be approached as a migraine-related condition, opening up new avenues for effective treatment strategies.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 33 Reviews
7.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Tension eased
13 people found this helpful
I've tried numerous magnesium supplements, but this one is exceptional. It alleviates my tension headaches and migraines, particularly the severe muscle spasms following a brain injury. I've learned that consuming carbonated drinks can exacerbate magnesium issues, leading to agonising muscle spasms. By taking this supplement after such beverages, I can avoid significant discomfort and enjoy its beneficial effects.
Read More
9
Headache relief
11 people found this helpful
The magnesium L-threonate supplement is the most absorbable form in the body. After a month of taking three capsules a day, I've noticed a significant reduction in stress and irritability, and I no longer suffer from headaches. My state of calm is now habitual, and my hair has also improved – they seem stronger and shinier. Although it is an expensive form of magnesium, it is high quality and effective. I highly recommend it!
Read More
10
Body aches gone
9 people found this helpful
This product has greatly improved my situation. Within a week, my usual body aches and headaches from insufficient sleep disappeared. Even while working long hours in cold weather, my cognitive abilities improved remarkably. I recommend starting slowly for better acclimation. Additionally, my hormonal balance has improved this month, making me consider never going without this supplement again.
Read More
7.5
Effective headaches relief
6 people found this helpful
This magnesium type (L-threonate) from Jarrow Formulas is very effective for headaches and migraines, as well as brain fog. It also aids with anxiety, depression, and muscle spasms. I take it alongside magnesium glycinate, potassium glycinate, and taurine with meals.
Read More
9
Headaches reduced
4 people found this helpful
I won't live without this product! Initially purchased for sleep enhancement, I've noticed a significant 90% reduction in my chronic tension headaches since consistent use. What a fantastic bonus.
Read More

Frequently Asked Questions

9
Headache gone
1 people found this helpful
I've been taking MagMind for two weeks and it has greatly improved my sleep quality. Most importantly, the frequent headaches I experienced have disappeared. I’m impressed compared to my previous use of Citrate. I will order more to keep on hand.
9
Headache relief
11 people found this helpful
The magnesium L-threonate supplement is the most absorbable form in the body. After a month of taking three capsules a day, I've noticed a significant reduction in stress and irritability, and I no longer suffer from headaches. My state of calm is now habitual, and my hair has also improved – they seem stronger and shinier. Although it is an expensive form of magnesium, it is high quality and effective. I highly recommend it!
9
Stress and headache
2 people found this helpful
The magnesium L-threonate supplement is incredibly absorbable. After taking three capsules daily for a month, I've noticed increased stress resistance, reduced irritability, and no headaches. My hair has improved too. While it’s a pricier option, it's high quality and effective. I recommend it!
0
Causes headaches
3 people found this helpful
Magtein provides mental clarity; however, it gives me severe headaches that persist for the first day or so. If I stop, I experience withdrawal symptoms such as migraines and lethargy for up to three days. Others may respond better than I do.
0
Slight headache
1 people found this helpful
It gave me a slight headache.
6
Headache control
2 people found this helpful
After a long search for this magnesium form that crosses the blood-brain barrier, I found it helpful for sleep and reducing my convulsions. Best of all, I have not had a headache during the two months of taking it, which is remarkable for me. It is somewhat expensive, so I plan to purchase it only once a year.
10
Headache remedy
3 people found this helpful
This is the best magnesium I have tried, and I've experimented with nearly all magnesium preparations from iHerb. It effectively stops my headaches due to its unique ability to penetrate the blood-brain barrier. I recommend it, especially for those with neurodegenerative and cognitive issues. My family, including my young daughter, takes it for improved brain function.
0
Causes headache
After the first dose, I immediately developed a headache and felt foggy all day. My husband didn't experience these side effects. Now he will take it; it seems to have calmed him.
7.5
Effective headaches relief
6 people found this helpful
This magnesium type (L-threonate) from Jarrow Formulas is very effective for headaches and migraines, as well as brain fog. It also aids with anxiety, depression, and muscle spasms. I take it alongside magnesium glycinate, potassium glycinate, and taurine with meals.
10
Headache relief
The best magnesium! It eliminated my headaches entirely. I've tested it on others too, and they agree.
7
Magnesium's efficacy for headaches
We explored the impact of magnesium treatment on headaches, focusing specifically on its role in preventing migraines. The evidence suggests that magnesium may be beneficial for some individuals in managing headache frequency and intensity. It is often recommended not only for migraine prevention but also for acute treatment when given intravenously.

Importantly, we noted that magnesium tends to have a good safety profile, with any adverse effects typically being mild and related to gastrointestinal tolerance. This makes it a potentially attractive option for those seeking relief from headaches. However, it's crucial to approach magnesium use with careful consideration, recognizing that responses can vary from person to person.

Overall, our examination highlights magnesium as a valuable tool in the headache management arsenal, although it should be part of a more comprehensive treatment strategy. Knowing its benefits allows us to better inform those struggling with headache disorders.
We conducted a study assessing how nonprescription therapies, particularly a combination product containing magnesium, affect symptoms of vestibular migraine (VM). Our research involved collecting data from patients diagnosed with VM who were given guidance on lifestyle changes, like hydration and nutrition, alongside the supplement.

After three months of treatment, we observed promising results. The severity and frequency of headache-related symptoms showed significant improvement based on assessments using established scales. For instance, participants reported a reduction in dizziness and headache intensity, with many noting a better quality of life.

Notably, half of the patients observed an enhancement in their symptoms, while most tolerated the supplement without any issues. These findings suggest that magnesium, when combined with other nutrients, could contribute positively to managing VM headaches.

Overall, our study offers preliminary support for magnesium's potential role in treating VM, particularly through a holistic approach that includes lifestyle modifications.
7
Magnesium shows potential benefits
The effectiveness of magnesium in treating headaches has garnered attention, particularly when we consider its potential role as a dietary supplement for both children and adults. In examining its impact, studies have indeed explored how magnesium may help alleviate headache symptoms.

Our review highlighted research findings that suggest magnesium may not only reduce headache frequency but also the intensity of pain experienced during episodes. Interestingly, some studies specifically noted that certain dietary supplements, including magnesium, could yield positive outcomes for individuals suffering from headaches.

It’s important to note, however, that while there are promising indications, the evaluation of magnesium's effectiveness often comes paired with other treatments. This raises questions about its isolated impact. Therefore, while there’s evidence pointing to magnesium's benefits, its exact role, particularly when not combined with other therapies, remains to be clarified.
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.

References

  1. Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. 10.3390/nu17040725
  2. Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. 10.1007/s11916-025-01358-3
  3. Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. 10.1111/imj.16314
  4. Mirzaeva LM, Lobzina AS, Akhmedova KN, Shvartsman GI, Kula II, et al. [Therapeutic approaches to comorbid pathology in episodic migraine and tension-type headache]. Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123:52. 10.17116/jnevro202312309152
  5. Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. 10.1007/s00482-023-00738-1
  6. Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. 10.1097/MOO.0000000000000908
  7. Verhaak A, Bakaysa S, Johnson A, Veronesi M, Williamson A, et al. Migraine treatment in pregnancy: A survey of comfort and treatment practices of women's healthcare providers. Headache. 2023;63:211. 10.1111/head.14436
  8. Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. 10.4103/0028-3886.359247
  9. Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, et al. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022;8:CD014978. 10.1002/14651858.CD014978.pub2
  10. Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
  11. Bharadwaj VN, Meyerowitz J, Zou B, Klukinov M, Yan N, et al. Impact of Magnesium on Oxytocin Receptor Function. Pharmaceutics. 2022;14. 10.3390/pharmaceutics14051105
  12. Martin BR. Multimodal Care for Headaches, Lumbopelvic Pain, and Dysmenorrhea in a Woman With Endometriosis: A Case Report. J Chiropr Med. 2021;20:148. 10.1016/j.jcm.2021.10.002
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