Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.9
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
8
We examined a patient who experienced severe anemia following COVID-19, presenting with both cold agglutinin and cryoglobulin. Testing showed positivity for C3d but no significant signs of hemolytic anemia or thrombosis.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Read More
Most Useful Reviews
7.5
Improved cold tolerance
47 people found this helpful
I have suffered from Chronic Fatigue Syndrome for many years. I tried a comparable product from Solgar, Metafolin, which worked but upset my stomach. This product does the same without causing any discomfort. It essentially alters my perception and tolerance to cold; I no longer feel it penetrating my bones as I did before. While it hasn't completely removed my brain fog, it has subtly improved my ability to focus, allowing me to concentrate better without the haze I previously experienced.
Read More
9
Prevented winter colds
These excellent vitamins come in a powerful dosage. Since I began taking them in January, I’ve noticed significant improvements. My energy levels have increased, leading to better sleep quality. Furthermore, I’ve not caught a cold during winter, a time when I typically get ill. Thanks to the dosage, I don’t have to take them daily, and it will last a long time.
Read More
7.5
Reduced cold extremities
1 people found this helpful
During winter, my fingertips would hurt from cold extremities. Since I’ve started taking methylfolic acid, this has improved remarkably. The capsule size is quite small, which I appreciate.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We examined a patient who experienced severe anemia following COVID-19, presenting with both cold agglutinin and cryoglobulin. Testing showed positivity for C3d but no significant signs of hemolytic anemia or thrombosis.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved cold tolerance
47 people found this helpful
I have suffered from Chronic Fatigue Syndrome for many years. I tried a comparable product from Solgar, Metafolin, which worked but upset my stomach. This product does the same without causing any discomfort. It essentially alters my perception and tolerance to cold; I no longer feel it penetrating my bones as I did before. While it hasn't completely removed my brain fog, it has subtly improved my ability to focus, allowing me to concentrate better without the haze I previously experienced.
Read More
9
Prevented winter colds
These excellent vitamins come in a powerful dosage. Since I began taking them in January, I’ve noticed significant improvements. My energy levels have increased, leading to better sleep quality. Furthermore, I’ve not caught a cold during winter, a time when I typically get ill. Thanks to the dosage, I don’t have to take them daily, and it will last a long time.
Read More
7.5
Reduced cold extremities
1 people found this helpful
During winter, my fingertips would hurt from cold extremities. Since I’ve started taking methylfolic acid, this has improved remarkably. The capsule size is quite small, which I appreciate.
Read More
9
Strengthened immunity
Though I've taken methyl folate for a short time, I’ve noticed improvements in my mood and immunity. I contracted a virus, but it barely affected me; I experienced just minor symptoms. Previously, my colds lasted longer. Doubling my daily dose has kept my strength intact, and I'm pleased with the supplement's quality and my improved sleep.
Read More
9
Quick recovery
I’ve been taking this supplement for a short period, and I’ve already noticed enhanced immunity. When I caught a virus, my symptoms were minimal and cleared up within two days. Previously, I would suffer from colds lasting much longer. After increasing my dose, I felt no residual weakness and was delighted with the quality of this product.
Read More
Frequently Asked Questions
9
Quick recovery
I’ve been taking this supplement for a short period, and I’ve already noticed enhanced immunity. When I caught a virus, my symptoms were minimal and cleared up within two days. Previously, I would suffer from colds lasting much longer. After increasing my dose, I felt no residual weakness and was delighted with the quality of this product.
9
Prevented winter colds
These excellent vitamins come in a powerful dosage. Since I began taking them in January, I’ve noticed significant improvements. My energy levels have increased, leading to better sleep quality. Furthermore, I’ve not caught a cold during winter, a time when I typically get ill. Thanks to the dosage, I don’t have to take them daily, and it will last a long time.
7.5
Effective viral support
I have taken this supplement for a short while and noticed a boost in my immune system. After catching a common virus, I recovered swiftly with only mild symptoms. I previously dealt with longer-lasting colds. Increasing my zinc intake also helped, and I remained strong throughout.
7.5
Improved cold tolerance
47 people found this helpful
I have suffered from Chronic Fatigue Syndrome for many years. I tried a comparable product from Solgar, Metafolin, which worked but upset my stomach. This product does the same without causing any discomfort. It essentially alters my perception and tolerance to cold; I no longer feel it penetrating my bones as I did before. While it hasn't completely removed my brain fog, it has subtly improved my ability to focus, allowing me to concentrate better without the haze I previously experienced.
7.5
Reduced cold extremities
1 people found this helpful
During winter, my fingertips would hurt from cold extremities. Since I’ve started taking methylfolic acid, this has improved remarkably. The capsule size is quite small, which I appreciate.
7.5
Quick cold recovery
I've taken this excellent methyl folate supplement for a short time and have noticed improved immunity. I recently caught a viral infection—possibly the most prevalent virus of 2020—but I recovered with minimal symptoms like a stuffy nose and general weakness, which lasted only 2 days. Previously, I had colds that lasted much longer. I doubled my daily dose during this time, and I was pleased to find my strength remained intact when I returned to the gym. I'm satisfied with the quality and ingredients.
7.5
Family cold remedy
This remedy is indispensable in our cold region. My entire family takes it from September to May, and it significantly reduces the frequency of our illnesses.
References
- Kaneko M, Masuda Y, Ishikawa K, Shikata H. Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection. Cureus. 2024;16:e75257. 10.7759/cureus.75257
