Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Moderately Good
Based on 46 Reviews
7.9
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
Read More
8
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Read More
7
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More
Most Useful Reviews
7.5
Reduced hair loss
33 people found this helpful
My research led me to this better form of folic acid. The small pill is easy to take, and since using it, my hair loss has significantly decreased and I sleep more soundly.
Read More
9
Mood and hair loss
10 people found this helpful
Methylfolate or vitamin B9 is of excellent quality with small capsules for easy swallowing. After using it for women's health, I've experienced improved mood, increased energy, and my hair loss has stopped.
Read More
9
Reduces hair loss
9 people found this helpful
Excellent! It has notably reduced my hair loss, but you must consume it on an empty stomach half an hour before breakfast. Please give a like.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
- All Researches
8
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Read More
8
Folic acid treatment shows promise
We explored the effects of folic acid on hair loss in a three-week-old Charolais calf showing signs typical of folic acid deficiency. After starting daily folic acid therapy at a dose of 1 mg/kg, we observed that the crusts and patches diminished within two weeks. Remarkably, hair growth resumed, and within two months, the calf returned to a normal state. This indicates that folic acid could be an effective treatment for certain types of alopecia related to deficiencies in this essential nutrient.
Read More
7
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Read More
7
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 46 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced hair loss
33 people found this helpful
My research led me to this better form of folic acid. The small pill is easy to take, and since using it, my hair loss has significantly decreased and I sleep more soundly.
Read More
9
Mood and hair loss
10 people found this helpful
Methylfolate or vitamin B9 is of excellent quality with small capsules for easy swallowing. After using it for women's health, I've experienced improved mood, increased energy, and my hair loss has stopped.
Read More
9
Reduces hair loss
9 people found this helpful
Excellent! It has notably reduced my hair loss, but you must consume it on an empty stomach half an hour before breakfast. Please give a like.
Read More
9
Moods improved
4 people found this helpful
Suffering from hair loss, I found that folic acid is crucial for healthy cell growth in skin, nails, and hair. After using this product, not only has my hair loss ceased, but my mood has also improved. Highly recommend!
Read More
9
Stops hair loss
1 people found this helpful
Truly wonderful! It stopped my hair loss quickly, even though that wasn't the primary aim of my purchase. I highly recommend it.
Read More
Frequently Asked Questions
10
Hair loss stopped
Excellent! My hair loss stopped immediately after starting this. It's the best folic acid for women, with superior absorption compared to pharmacy alternatives. You will definitely benefit from it!
9
Restored hair growth
An excellent supplement ordered to eliminate B9 deficiency. The active form of folic acid ensures better absorption. After two months, my hair loss has been restored, and growth has accelerated!
9
Moods improved
4 people found this helpful
Suffering from hair loss, I found that folic acid is crucial for healthy cell growth in skin, nails, and hair. After using this product, not only has my hair loss ceased, but my mood has also improved. Highly recommend!
7.5
Reduced hair loss
33 people found this helpful
My research led me to this better form of folic acid. The small pill is easy to take, and since using it, my hair loss has significantly decreased and I sleep more soundly.
9
Mood and hair loss
10 people found this helpful
Methylfolate or vitamin B9 is of excellent quality with small capsules for easy swallowing. After using it for women's health, I've experienced improved mood, increased energy, and my hair loss has stopped.
9
Enhanced hair health
Methylfolate enhances hair health, halts hair loss, provides a natural shine, and strengthens the nail plate, preventing brittleness and peeling.
8
Visible improvement
Taking this along with other vitamins, I am fighting hair loss. The results are visible, and I am very pleased!
9
Hair improvement noted
Methyl folate is akin to folic acid and is beneficial for hair, nails, and skin. I noticed improvements in my hair, hair loss ceased, and my nails became better during its use.
9
Daily requirement met
Excellent, it has stopped my hair loss, and 400 mg is the daily requirement for folic acid.
9
Reduces hair loss
9 people found this helpful
Excellent! It has notably reduced my hair loss, but you must consume it on an empty stomach half an hour before breakfast. Please give a like.
8
We explored the effectiveness of two nutritional supplements for treating telogen effluvium (TE), a common form of hair loss. Over 180 days, female participants received either a nutrient-rich supplement containing folic acid or an alternative formulation.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
Our clinical evaluations revealed significant improvements in hair loss, volume, and overall hair health in the group receiving the first supplement, especially noticeable within the first 90 days. The second group, however, did not show substantial changes in all parameters.
This study suggests that nutrition plays a crucial role in managing TE, reaffirming the benefits of specific supplements.
7
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
References
- Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. 10.2147/CCID.S173082
- Bouvet A, Baird JD, Basrur PK. Folic acid therapy for alopecia in a Charolais calf. Vet Rec. 1988;123:533.
- Riegel K, Hengl T, Krischok S, Schlinzig K, Abts HF. L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes. Clin Cosmet Investig Dermatol. 2020;13:499. 10.2147/CCID.S254720
- Rah YC, Park S, Koun S, Park HC, Choi J. In vivo assay of the ethanol-induced embryonic hair cell loss and the protective role of the retinoic and folic acid in zebrafish larvae (Danio rerio). Alcohol. 2019;75:113. 10.1016/j.alcohol.2018.07.008
