Last update
4/4/2026
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 9 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
9
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
Read More
9
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
Read More
Most Useful Reviews
9
Cycle regularity
1 people found this helpful
Following my doctor's recommendation, I take this folate regularly and have experienced pleasing results: my cycle is now regular, and my pelvic pain has disappeared.
Read More
9
Cramp improvement
I didn’t notice obvious changes while taking this, but my pelvic cramps remarkably improved, changing from excruciating pain to manageable discomfort.
Read More
9
Menstrual pain relief
Very small, convenient capsules that helped alleviate my pelvic pain during menstruation.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
- All Researches
9
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
Read More
9
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cycle regularity
1 people found this helpful
Following my doctor's recommendation, I take this folate regularly and have experienced pleasing results: my cycle is now regular, and my pelvic pain has disappeared.
Read More
9
Cramp improvement
I didn’t notice obvious changes while taking this, but my pelvic cramps remarkably improved, changing from excruciating pain to manageable discomfort.
Read More
9
Menstrual pain relief
Very small, convenient capsules that helped alleviate my pelvic pain during menstruation.
Read More
9
No stomach issues
3 people found this helpful
This product has a natural folic acid formulation and does not cause any stomach pain, which I've appreciated.
Read More
8
Pain reduction
1 people found this helpful
Good gynaecologists keep up with the times. They recommend starting methylfolate instead of folic acid for those planning pregnancy, as folic acid may not absorb well. After taking this vitamin, I noticed my cycle became more regular, with significantly reduced pelvic pain during my periods. This positive change occurred after just one jar for both my husband and me. I believe this vitamin is well absorbed and will yield good results!
Read More
Frequently Asked Questions
9
Cramp improvement
I didn’t notice obvious changes while taking this, but my pelvic cramps remarkably improved, changing from excruciating pain to manageable discomfort.
0
Not effective
1 people found this helpful
To be honest, I didn't like these folates. After taking them, I experienced lower abdominal pain. Perhaps it's a coincidence, but the pain disappeared once I stopped taking the pills.
7.5
Effective remedy
1 people found this helpful
I took this supplement to maintain my women's health, following my doctor's advice. Although I'm not planning a pregnancy yet, I will buy this product when I do. It worked well with evening primrose oil: my pelvic pain during my period decreased, and overall, it seems beneficial for my cardiovascular health.
9
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.
Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
9
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
References
- Zheng J, Hu R, Yang Y, Wang Y, Wang Q, et al. Antibiotic-loaded reactive oxygen species-responsive nanomedicine for effective management of chronic bacterial prostatitis. Acta Biomater. 2022;143:471. 10.1016/j.actbio.2022.02.044
- Macchione N, Bernardini P, Piacentini I, Mangiarotti B, Del Nero A. Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments. Antiinflamm Antiallergy Agents Med Chem. 2019;18:151. 10.2174/1871523018666181128164252
Data last updated:
