Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 13 Reviews
7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%

Top Medical Research Studies

We reviewed numerous studies to understand the skin reactions stemming from Methotrexate (MTX). Our analysis included data from over 8,000 papers, ultimately focusing on 31 relevant studies involving 38 patients.

Common skin issues included severe conditions like toxic epidermal necrolysis and erythema multiforme. While we found that immediate withdrawal of MTX and treatments, including folic acid supplementation, were beneficial, it's clear that healthcare providers must recognize these possible reactions to prevent severe consequences.
Read More

Most Useful Reviews

7
Cell growth support
14 people found this helpful
High-quality, strong methylfolate. It promotes cell growth and renewal, enhances the functioning of the brain, heart, and blood vessels, while also preventing fatty infiltration of the liver. This supplement helps women maintain their youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing the skin of rashes, especially beneficial for those pregnant or planning a pregnancy.
Read More
0
Painful side effects
5 people found this helpful
I can't say the pills are effective, as they cause painful rashes on my body after taking them.
Read More
6
Effective for hair
110 people found this helpful
Previously, I thought only pregnant women took folic acid, but I've learned that it aids in the renewal of hair follicles, slows down wrinkle formation, and cleanses the skin of rashes. I ordered folate on a friend's advice, as it is a natural form of vitamin B-9. I am pleased with the results; my hair has strengthened and hardly falls out.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
We reviewed numerous studies to understand the skin reactions stemming from Methotrexate (MTX). Our analysis included data from over 8,000 papers, ultimately focusing on 31 relevant studies involving 38 patients.

Common skin issues included severe conditions like toxic epidermal necrolysis and erythema multiforme. While we found that immediate withdrawal of MTX and treatments, including folic acid supplementation, were beneficial, it's clear that healthcare providers must recognize these possible reactions to prevent severe consequences.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 13 Reviews
7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7
Cell growth support
14 people found this helpful
High-quality, strong methylfolate. It promotes cell growth and renewal, enhances the functioning of the brain, heart, and blood vessels, while also preventing fatty infiltration of the liver. This supplement helps women maintain their youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing the skin of rashes, especially beneficial for those pregnant or planning a pregnancy.
Read More
0
Painful side effects
5 people found this helpful
I can't say the pills are effective, as they cause painful rashes on my body after taking them.
Read More
6
Effective for hair
110 people found this helpful
Previously, I thought only pregnant women took folic acid, but I've learned that it aids in the renewal of hair follicles, slows down wrinkle formation, and cleanses the skin of rashes. I ordered folate on a friend's advice, as it is a natural form of vitamin B-9. I am pleased with the results; my hair has strengthened and hardly falls out.
Read More
6
Better than others
7 people found this helpful
Methylfolate is a B9 vitamin I take to support my eyes, thyroid, and nervous system. I consume it in cycles: two to three times a year, and it works well. Previously, I used another brand, but I find this to be even better in terms of quality and packaging. Metafolin also helps women maintain youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing skin of rashes.
Read More
2
No noticeable benefits
4 people found this helpful
I took folic acid for a long time with no noticeable benefit. Despite being a digestible form that ideally produces results, it wasn't effective for me. It is vital for pregnant women in promoting fetal nerve tube development, but I couldn’t continue with Solar as it gave me rashes.
Read More

Frequently Asked Questions

2
No noticeable benefits
4 people found this helpful
I took folic acid for a long time with no noticeable benefit. Despite being a digestible form that ideally produces results, it wasn't effective for me. It is vital for pregnant women in promoting fetal nerve tube development, but I couldn’t continue with Solar as it gave me rashes.
6
Effective for hair
110 people found this helpful
Previously, I thought only pregnant women took folic acid, but I've learned that it aids in the renewal of hair follicles, slows down wrinkle formation, and cleanses the skin of rashes. I ordered folate on a friend's advice, as it is a natural form of vitamin B-9. I am pleased with the results; my hair has strengthened and hardly falls out.
6
Better than others
7 people found this helpful
Methylfolate is a B9 vitamin I take to support my eyes, thyroid, and nervous system. I consume it in cycles: two to three times a year, and it works well. Previously, I used another brand, but I find this to be even better in terms of quality and packaging. Metafolin also helps women maintain youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing skin of rashes.
0
Painful side effects
5 people found this helpful
I can't say the pills are effective, as they cause painful rashes on my body after taking them.
7
Cell growth support
14 people found this helpful
High-quality, strong methylfolate. It promotes cell growth and renewal, enhances the functioning of the brain, heart, and blood vessels, while also preventing fatty infiltration of the liver. This supplement helps women maintain their youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing the skin of rashes, especially beneficial for those pregnant or planning a pregnancy.
2
Individual intolerance noticed
A good medication, but unfortunately, I have an individual intolerance to it, resulting in a rash. I gave it to my mother and she has responded well; tests show her folic acid levels are increasing, indicating it is being absorbed.
7
High bioavailability
Metafolin tablets with 400 mcg of folic acid are recommended as a biologically active food supplement. They provide high bioavailability and help compensate for vitamin deficiencies. This supplement promotes cell growth, improves heart and brain function, and prevents fatty liver infiltration. It renews hair follicles, slows wrinkle formation, and clears skin of rashes. My husband and I have been taking it on our doctor’s recommendation.

References

  1. Zuber M, Chhabra M, Venkataraman R, Kumar S, Rashid M. Methotrexate related cutaneous adverse drug reactions: a systematic literature review. J Basic Clin Physiol Pharmacol. 2022;33:549. doi:10.1515/jbcpp-2021-0165
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