We reviewed numerous studies to understand the skin reactions stemming from Methotrexate (MTX). Our analysis included data from over 8,000 papers, ultimately focusing on 31 relevant studies involving 38 patients.
Common skin issues included severe conditions like toxic epidermal necrolysis and erythema multiforme. While we found that immediate withdrawal of MTX and treatments, including folic acid supplementation, were beneficial, it's clear that healthcare providers must recognize these possible reactions to prevent severe consequences.
Read More
Most Useful Reviews
7
Cell growth support
14 people found this helpful
High-quality, strong methylfolate. It promotes cell growth and renewal, enhances the functioning of the brain, heart, and blood vessels, while also preventing fatty infiltration of the liver. This supplement helps women maintain their youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing the skin of rashes, especially beneficial for those pregnant or planning a pregnancy.
Read More
0
Painful side effects
5 people found this helpful
I can't say the pills are effective, as they cause painful rashes on my body after taking them.
Read More
6
Effective for hair
110 people found this helpful
Previously, I thought only pregnant women took folic acid, but I've learned that it aids in the renewal of hair follicles, slows down wrinkle formation, and cleanses the skin of rashes. I ordered folate on a friend's advice, as it is a natural form of vitamin B-9. I am pleased with the results; my hair has strengthened and hardly falls out.
We reviewed numerous studies to understand the skin reactions stemming from Methotrexate (MTX). Our analysis included data from over 8,000 papers, ultimately focusing on 31 relevant studies involving 38 patients.
Common skin issues included severe conditions like toxic epidermal necrolysis and erythema multiforme. While we found that immediate withdrawal of MTX and treatments, including folic acid supplementation, were beneficial, it's clear that healthcare providers must recognize these possible reactions to prevent severe consequences.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 13 Reviews
7
All Reviews
Positive Reviews
Negative Reviews
7
Cell growth support
14 people found this helpful
High-quality, strong methylfolate. It promotes cell growth and renewal, enhances the functioning of the brain, heart, and blood vessels, while also preventing fatty infiltration of the liver. This supplement helps women maintain their youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing the skin of rashes, especially beneficial for those pregnant or planning a pregnancy.
Read More
0
Painful side effects
5 people found this helpful
I can't say the pills are effective, as they cause painful rashes on my body after taking them.
Read More
6
Effective for hair
110 people found this helpful
Previously, I thought only pregnant women took folic acid, but I've learned that it aids in the renewal of hair follicles, slows down wrinkle formation, and cleanses the skin of rashes. I ordered folate on a friend's advice, as it is a natural form of vitamin B-9. I am pleased with the results; my hair has strengthened and hardly falls out.
Read More
6
Better than others
7 people found this helpful
Methylfolate is a B9 vitamin I take to support my eyes, thyroid, and nervous system. I consume it in cycles: two to three times a year, and it works well. Previously, I used another brand, but I find this to be even better in terms of quality and packaging. Metafolin also helps women maintain youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing skin of rashes.
Read More
2
No noticeable benefits
4 people found this helpful
I took folic acid for a long time with no noticeable benefit. Despite being a digestible form that ideally produces results, it wasn't effective for me. It is vital for pregnant women in promoting fetal nerve tube development, but I couldn’t continue with Solar as it gave me rashes.
A rash is a noticeable change in the texture or color of the skin that can manifest in various ways, including redness, swelling, itching, or blistering. Rashes can result from a wide range of causes, such as allergies, irritants, infections, or skin conditions like eczema or psoriasis. While some rashes may be mild and resolve on their own, others might require medical attention, particularly if they are persistent, widespread, or accompanied by other symptoms like fever or pain.
Identifying the underlying cause of a rash is crucial for effective treatment. Over-the-counter antihistamines or hydrocortisone creams can alleviate mild allergic reactions or irritations. However, for more severe cases or rashes that worsen, consulting a healthcare professional is recommended to ensure proper diagnosis and treatment options. Overall, being proactive and understanding the potential triggers of rashes can help in managing and preventing them in the future.
Folic acid, also known as vitamin B9, is a water-soluble vitamin that plays a crucial role in many bodily functions, particularly in the synthesis of DNA and RNA. It is essential for cell division and is especially important during periods of rapid growth, such as during pregnancy and infancy. The body cannot produce folic acid on its own, which is why it must be obtained from dietary sources or supplements. Commonly found in leafy green vegetables, legumes, seeds, and fortified foods, folic acid is vital for preventing neural tube defects in developing fetuses and is often recommended for women of childbearing age.
In addition to its key role in pregnancy, folic acid contributes to the production of red blood cells and can help reduce the risk of certain types of anemia. Research has also suggested that adequate folic acid levels may be associated with lowered risk of heart disease and other health issues. Most health organizations recommend a daily intake of 400 micrograms for adults, with higher amounts suggested for pregnant women. Incorporating folate-rich foods into your diet, or considering supplementation, can help ensure you meet your folic acid needs.
Based on user reviews, the timeline for seeing results from methylfolate supplements, particularly in relation to skin rashes, seems to vary. While some users have reported improvements in their skin and overall well-being, others have mentioned a lack of noticeable benefits or even adverse reactions such as rashes. For instance, a user indicated they took folic acid for a long time without seeing any significant results and unfortunately experienced rashes after using it Read Review. Conversely, another user noted that the supplement was effective in cleansing the skin of rashes and praised its overall benefits, suggesting that some users did experience positive changes over time Read Review.
Based on user reviews, many individuals have reported positive improvements in symptoms related to hair health, skin condition, and overall vitality when using methylfolate supplements. Several users noted that their hair became stronger and showed reduced hair loss, reinforcing the supplement's purported ability to renew hair follicles and slow down wrinkle formation Read Review. Additionally, users indicated improvements in skin clarity, with some asserting that it helped cleanse their skin of rashes that they previously struggled with Read Review.
However, it's essential to clarify that individual results can vary widely. While many users celebrated benefits such as enhanced beauty and vitality, others had less favorable experiences, including adverse effects like painful rashes Read Review or no noticeable improvements Read Review. Ultimately, these varied experiences highlight the importance of considering personalized responses to supplements.
Based on user reviews, experiences with combining methylfolate supplements, specifically for managing skin rashes, yield diverse outcomes. Many users have highlighted the benefits of methylfolate supplements in cleansing skin of rashes, as noted by several users who praised its effectiveness in renewing hair follicles, slowing wrinkle formation, and clearing skin issues Read ReviewRead Review. One user reported significant positive changes, such as stronger hair and improved skin conditions Read Review.
However, not all users have experienced similar results. Some reported adverse reactions, including painful rashes that surfaced after taking the supplement. These mixed responses suggest that while methylfolate may be beneficial for some, others might encounter intolerances or side effects, as documented by users who experienced discomfort and rashes Read ReviewRead Review. Overall, combining methylfolate with other supplements appears to be a highly individualized experience, with varying levels of efficacy in managing rashes.
Based on user reviews, there seems to be a general consensus that methylfolate, a strong form of folic acid, is beneficial for skin health and can help clear rashes. Many users noted improvements in their skin condition alongside other benefits such as hair follicle renewal and wrinkle reduction when using methylfolate, particularly in doses around 400 mcg, which are commonly recommended for both pregnant women and general health enhancement Read Review. However, some users did report adverse effects, including painful rashes attributed to taking folic acid, indicating that individual responses can vary greatly Read Review.
Furthermore, while some users espoused positive outcomes with consistent use, others felt it was ineffective or caused undesirable side effects. For instance, one review highlighted a lack of noticeable benefits despite long-term use, suggesting that dosage might not be the sole factor for efficacy, as individual tolerances also play a significant role Read Review. Therefore, while the suggested dosage appears effective for many, it is important for individuals to monitor their own responses and consult with healthcare professionals if they experience any adverse reactions.
2
No noticeable benefits
4 people found this helpful
I took folic acid for a long time with no noticeable benefit. Despite being a digestible form that ideally produces results, it wasn't effective for me. It is vital for pregnant women in promoting fetal nerve tube development, but I couldn’t continue with Solar as it gave me rashes.
6
Effective for hair
110 people found this helpful
Previously, I thought only pregnant women took folic acid, but I've learned that it aids in the renewal of hair follicles, slows down wrinkle formation, and cleanses the skin of rashes. I ordered folate on a friend's advice, as it is a natural form of vitamin B-9. I am pleased with the results; my hair has strengthened and hardly falls out.
6
Better than others
7 people found this helpful
Methylfolate is a B9 vitamin I take to support my eyes, thyroid, and nervous system. I consume it in cycles: two to three times a year, and it works well. Previously, I used another brand, but I find this to be even better in terms of quality and packaging. Metafolin also helps women maintain youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing skin of rashes.
0
Painful side effects
5 people found this helpful
I can't say the pills are effective, as they cause painful rashes on my body after taking them.
7
Cell growth support
14 people found this helpful
High-quality, strong methylfolate. It promotes cell growth and renewal, enhances the functioning of the brain, heart, and blood vessels, while also preventing fatty infiltration of the liver. This supplement helps women maintain their youth and beauty by renewing hair follicles, slowing down wrinkle formation, and cleansing the skin of rashes, especially beneficial for those pregnant or planning a pregnancy.
2
Individual intolerance noticed
A good medication, but unfortunately, I have an individual intolerance to it, resulting in a rash. I gave it to my mother and she has responded well; tests show her folic acid levels are increasing, indicating it is being absorbed.
7
High bioavailability
Metafolin tablets with 400 mcg of folic acid are recommended as a biologically active food supplement. They provide high bioavailability and help compensate for vitamin deficiencies. This supplement promotes cell growth, improves heart and brain function, and prevents fatty liver infiltration. It renews hair follicles, slows wrinkle formation, and clears skin of rashes. My husband and I have been taking it on our doctor’s recommendation.
References
Zuber M, Chhabra M, Venkataraman R, Kumar S, Rashid M. Methotrexate related cutaneous adverse drug reactions: a systematic literature review. J Basic Clin Physiol Pharmacol. 2022;33:549. doi:10.1515/jbcpp-2021-0165