Medical Researches
Moderately Effective
Based on 3 Researches
We observed a case involving a 20-year-old woman with Type 1 diabetes experiencing persistent gastrointestinal issues, including diarrhea and nausea. Her medical journey led her to be diagnosed with autoimmune gastritis, an uncommon but important condition.
In the course of her treatment, we noticed her Vitamin B12 levels were not deficient, which is traditionally expected with autoimmune gastritis. Despite this, she was given parenteral Vitamin B12 therapy due to her neurological symptoms.
This case highlights that even when Vitamin B12 deficiency isn’t present, administration of Vitamin B12 can still provide significant relief from symptoms related to autoimmune gastritis. We learned that prompt treatment can prevent further neurological damage and improve overall quality of life for patients with autoimmune conditions.
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We explored the effects of vitamin B12 treatment alongside folic acid supplements in patients suffering from chronic atrophic gastritis (CAG). In a study involving 96 patients, we compared three treatment groups: those receiving weifuchun (a traditional treatment), those given weifuchun and folic acid, and those who had weifuchun, folic acid, and vitamin B12.
Although the presence of vitamin B12 in the treatment regimen was assessed, its isolated impact on gastritis cannot be conclusively determined due to the combination with other treatments. Mainly, we noted that the overall improvement in atrophic lesions was attributed to the combination of treatments rather than specifically to vitamin B12 alone.
The results showed a significant improvement in gastric atrophy, especially for those who received 5 mg of folic acid daily. However, we did not find separate evidence of a notable benefit from vitamin B12 treatment alone. This reveals the complexity of treating gastritis and the need for further research to validate the role of vitamin B12 independently.
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Vitamin B12 deficiency in AIGIron and Vitamin B12 Deficiency in Patients with Autoimmune Gastritis and Helicobacter pylori Gastritis: Results from a Prospective Multicenter Study.
Moderate relevance, treatment not evaluated
We observed a significant connection between vitamin B12 deficiency and autoimmune gastritis (AIG) in our study. By examining groups of patients with AIG, Helicobacter pylori-related gastritis, and healthy controls, we found that vitamin B12 levels were notably lower in those with AIG. Specifically, 13.3% of AIG patients experienced vitamin B12 deficiency compared to just 1.5% and 2.8% in the other groups.
Although our research indicates a clear link between AIG and reduced vitamin B12 levels, we did not evaluate the isolated effectiveness of vitamin B12 treatment on gastritis itself. This lack of specific treatment analysis means we can't definitively say that supplementing with vitamin B12 will alleviate gastritis symptoms.
Overall, the findings emphasize the importance of monitoring vitamin B12 levels in severe cases of atrophic gastritis, particularly for those diagnosed with AIG. Together, we can acknowledge that while there may be a relationship, further investigation is needed to understand the therapeutic potential of vitamin B12 for gastritis effectively.
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