Vitamin B12 aids tendon healingBlocking proteinase-activated receptor 2 signaling relieves pain, suppresses nerve sprouting, improves tissue repair, and enhances analgesic effect of B vitamins in rats with Achilles tendon injury.
Moderate relevance to tendonitis treatment
We explored the effects of the vitamin B complex, particularly focusing on vitamin B12, in treating pain and promoting recovery from Achilles tendon injuries. The study showed that tendon injury leads to significant pain and nerve changes, largely due to the activation of proteinase-activated receptor 2 (PAR2). By blocking this receptor, we observed a noteworthy decrease in pain and nerve sprouting, alongside improved structural healing of the tendon.
Vitamin B complex, which includes B12, played a key role by suppressing PAR2 activation. This suppression resulted in reduced pain and offered a boost to the healing process in the affected tendons. The findings suggest that vitamin B12, when used in combination with other vitamins, could indeed provide relief for tendonitis-related pain and help support tissue repair.
Overall, these insights into vitamin B12 and its beneficial effects signal a promising direction for future treatments of tendon injuries. It highlights the potential of integrating such vitamins into pain management strategies for tendon injuries, which often pose significant challenges.
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