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SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B12(as Methylcobalamin)
5,000 mcg
208,330%
Top Medical Research Studies
9
Vitamin B12 helps alleviate sciatica
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Directly addresses vitamin B12 efficacy
We conducted a double-blind, randomized, placebo-controlled study to explore the effectiveness of intramuscular vitamin B12 in treating low back pain, including cases of sciatica. A total of 60 patients between the ages of 18 and 65, all suffering from mechanical lumbago or sciatic neuritis, participated in the study over a period of time. Each patient had a solid medical history of back pain lasting from 6 months to 5 years, with significant pain intensity measured on a scale.
Throughout the study, both groups showed notable reductions in pain and disability. However, when we compared the active treatment with the placebo, the results favored vitamin B12 significantly; the differences were strikingly marked in measurement tools used for assessing pain and disability. Furthermore, the placebo group reported higher consumption of paracetamol compared to those receiving vitamin B12, indicating that this vitamin could effectively alleviate pain and the need for additional pain relief medications.
Overall, our findings support the potential of vitamin B12 injections in managing low back pain and sciatica for those without signs of nutritional deficiency.
Throughout the study, both groups showed notable reductions in pain and disability. However, when we compared the active treatment with the placebo, the results favored vitamin B12 significantly; the differences were strikingly marked in measurement tools used for assessing pain and disability. Furthermore, the placebo group reported higher consumption of paracetamol compared to those receiving vitamin B12, indicating that this vitamin could effectively alleviate pain and the need for additional pain relief medications.
Overall, our findings support the potential of vitamin B12 injections in managing low back pain and sciatica for those without signs of nutritional deficiency.
Read More
7
Vitamin B12 aids nerve recovery
Comparative evaluation of the electrophysiological, functional and ultrastructural effects of alpha lipoic acid and cyanocobalamin administration in a rat model of sciatic nerve injury.
Mixed evaluation of benefits
We explored the regenerative and protective effects of vitamin B12 on rats with sciatic nerve injuries. In the study, 40 rats were divided into several groups, including a control group, a sham group, and groups treated with either saline, alpha lipoic acid (ALA), or vitamin B12. Each treatment lasted for 12 weeks following the nerve injury.
Our findings revealed that while vitamin B12 showed some positive effects on nerve recovery, particularly in reducing edema and improving myelination, ALA treatment outperformed it in functional recovery measures. We noted significant improvements in the sciatic functional index for ALA-treated rats compared to those receiving vitamin B12.
The study highlighted the importance of understanding both the structural and functional aspects of nerve recovery. Even though vitamin B12 contributed favorably towards recovery, the results demonstrated that ALA might be a more effective option for enhancing movement and functionality after sciatic nerve injury.
Our findings revealed that while vitamin B12 showed some positive effects on nerve recovery, particularly in reducing edema and improving myelination, ALA treatment outperformed it in functional recovery measures. We noted significant improvements in the sciatic functional index for ALA-treated rats compared to those receiving vitamin B12.
The study highlighted the importance of understanding both the structural and functional aspects of nerve recovery. Even though vitamin B12 contributed favorably towards recovery, the results demonstrated that ALA might be a more effective option for enhancing movement and functionality after sciatic nerve injury.
Read More
Most Useful Reviews
8.8
Helps with sciatica
I truly enjoy this brand of methylcobalamin. The taste is delightful, making it a hit with the kids. I experience twitchy toes due to my nerves, and this product significantly alleviates that discomfort. I also believe it aids with my sciatica.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
9
Vitamin B12 helps alleviate sciatica
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Directly addresses vitamin B12 efficacy
We conducted a double-blind, randomized, placebo-controlled study to explore the effectiveness of intramuscular vitamin B12 in treating low back pain, including cases of sciatica. A total of 60 patients between the ages of 18 and 65, all suffering from mechanical lumbago or sciatic neuritis, participated in the study over a period of time. Each patient had a solid medical history of back pain lasting from 6 months to 5 years, with significant pain intensity measured on a scale.
Throughout the study, both groups showed notable reductions in pain and disability. However, when we compared the active treatment with the placebo, the results favored vitamin B12 significantly; the differences were strikingly marked in measurement tools used for assessing pain and disability. Furthermore, the placebo group reported higher consumption of paracetamol compared to those receiving vitamin B12, indicating that this vitamin could effectively alleviate pain and the need for additional pain relief medications.
Overall, our findings support the potential of vitamin B12 injections in managing low back pain and sciatica for those without signs of nutritional deficiency.
Throughout the study, both groups showed notable reductions in pain and disability. However, when we compared the active treatment with the placebo, the results favored vitamin B12 significantly; the differences were strikingly marked in measurement tools used for assessing pain and disability. Furthermore, the placebo group reported higher consumption of paracetamol compared to those receiving vitamin B12, indicating that this vitamin could effectively alleviate pain and the need for additional pain relief medications.
Overall, our findings support the potential of vitamin B12 injections in managing low back pain and sciatica for those without signs of nutritional deficiency.
Read More
7
Vitamin B12 aids nerve recovery
Comparative evaluation of the electrophysiological, functional and ultrastructural effects of alpha lipoic acid and cyanocobalamin administration in a rat model of sciatic nerve injury.
Mixed evaluation of benefits
We explored the regenerative and protective effects of vitamin B12 on rats with sciatic nerve injuries. In the study, 40 rats were divided into several groups, including a control group, a sham group, and groups treated with either saline, alpha lipoic acid (ALA), or vitamin B12. Each treatment lasted for 12 weeks following the nerve injury.
Our findings revealed that while vitamin B12 showed some positive effects on nerve recovery, particularly in reducing edema and improving myelination, ALA treatment outperformed it in functional recovery measures. We noted significant improvements in the sciatic functional index for ALA-treated rats compared to those receiving vitamin B12.
The study highlighted the importance of understanding both the structural and functional aspects of nerve recovery. Even though vitamin B12 contributed favorably towards recovery, the results demonstrated that ALA might be a more effective option for enhancing movement and functionality after sciatic nerve injury.
Our findings revealed that while vitamin B12 showed some positive effects on nerve recovery, particularly in reducing edema and improving myelination, ALA treatment outperformed it in functional recovery measures. We noted significant improvements in the sciatic functional index for ALA-treated rats compared to those receiving vitamin B12.
The study highlighted the importance of understanding both the structural and functional aspects of nerve recovery. Even though vitamin B12 contributed favorably towards recovery, the results demonstrated that ALA might be a more effective option for enhancing movement and functionality after sciatic nerve injury.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Helps with sciatica
I truly enjoy this brand of methylcobalamin. The taste is delightful, making it a hit with the kids. I experience twitchy toes due to my nerves, and this product significantly alleviates that discomfort. I also believe it aids with my sciatica.
