5/21/2025
Last update
5/21/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Moderately Good
Based on 24 Reviews
7.8
Supplement Facts
Serving Size: 2 Capsule
Amount Per Serving
%DV
Sulforaphane Glucosinolate(from Broccoli Seed Extract [Brassica oleracea L. Italica] in a Proprietary Blend Containing Myrosinase Enzyme)
35 mg
†
Top Medical Research Studies
9.5
We examined the effects of sulforaphane, a compound in broccoli, on lung cancer treatment. Our research focused on its ability to stop cell growth and induce cell death in lung adenocarcinoma cells, revealing that it can significantly halt tumor growth in animal models.
The study found that sulforaphane led to a marked reduction in tumor weight compared to untreated mice. While these results are promising for broccoli-derived treatments, further research is essential to understand its full potential in human applications, as we still need to see how these findings translate to actual lung cancer patients.
The study found that sulforaphane led to a marked reduction in tumor weight compared to untreated mice. While these results are promising for broccoli-derived treatments, further research is essential to understand its full potential in human applications, as we still need to see how these findings translate to actual lung cancer patients.
Read More
9
We explored the potential of broccoli's polysaccharides to fight lung cancer metastasis. In our study, we isolated three types of polysaccharides and found that BCE-I showed notable anti-metastatic properties when tested in mouse models. This fraction notably boosted immune responses, enhancing the activity of natural killer (NK) cells against tumor cells. While BCE-I demonstrated significant effects in reducing lung metastasis when administered both intravenously and orally, the results suggest that its effectiveness depends largely on active NK cell function. Thus, while promising, the findings warrant further investigation and optimization.
Read More
9
Sulforaphane shows limited lung cancer efficacy
We delved into the effects of sulforaphane, a compound abundant in broccoli, particularly its sprouts, on lung cancer prevention. Our review highlighted various clinical trials demonstrating that sulforaphane shows promise as an antitumor agent across multiple cancer types. While we observed significant results in some instances, the benefits were sometimes reduced in certain animal models.
Overall, while broccoli and its sulforaphane content have exciting potential, findings suggest that further research is necessary to establish consistent benefits for lung cancer specifically.
Overall, while broccoli and its sulforaphane content have exciting potential, findings suggest that further research is necessary to establish consistent benefits for lung cancer specifically.
Read More
Most Useful Reviews
9
Inflammation reduction
3 people found this helpful
Broccoli sprouts are effective in cancer prevention and reducing digestive inflammation. Sulforaphane induces cancer cell apoptosis and diminishes DNA damage. These vegetable capsules serve as a convenient and beneficial alternative for me, as they help maintain intestinal health and prevent cancer.
Read More
9
Effective detoxification
Sulforaphane not only prevents harmful substances from becoming carcinogens but also helps convert them into water-soluble substances that can be eliminated from the body.
Read More
7.5
Slowed progression
10 people found this helpful
Using Jarrow Formulas, Brocco Max has seemingly arrested the growth rate of my Prostate Cancer. While certainty is elusive, I’ve noticed significant improvement since starting this supplement.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
- All Researches
9.5
We examined the effects of sulforaphane, a compound in broccoli, on lung cancer treatment. Our research focused on its ability to stop cell growth and induce cell death in lung adenocarcinoma cells, revealing that it can significantly halt tumor growth in animal models.
The study found that sulforaphane led to a marked reduction in tumor weight compared to untreated mice. While these results are promising for broccoli-derived treatments, further research is essential to understand its full potential in human applications, as we still need to see how these findings translate to actual lung cancer patients.
The study found that sulforaphane led to a marked reduction in tumor weight compared to untreated mice. While these results are promising for broccoli-derived treatments, further research is essential to understand its full potential in human applications, as we still need to see how these findings translate to actual lung cancer patients.
Read More
9
We explored the potential of broccoli's polysaccharides to fight lung cancer metastasis. In our study, we isolated three types of polysaccharides and found that BCE-I showed notable anti-metastatic properties when tested in mouse models. This fraction notably boosted immune responses, enhancing the activity of natural killer (NK) cells against tumor cells. While BCE-I demonstrated significant effects in reducing lung metastasis when administered both intravenously and orally, the results suggest that its effectiveness depends largely on active NK cell function. Thus, while promising, the findings warrant further investigation and optimization.
Read More
9
Sulforaphane shows limited lung cancer efficacy
We delved into the effects of sulforaphane, a compound abundant in broccoli, particularly its sprouts, on lung cancer prevention. Our review highlighted various clinical trials demonstrating that sulforaphane shows promise as an antitumor agent across multiple cancer types. While we observed significant results in some instances, the benefits were sometimes reduced in certain animal models.
Overall, while broccoli and its sulforaphane content have exciting potential, findings suggest that further research is necessary to establish consistent benefits for lung cancer specifically.
Overall, while broccoli and its sulforaphane content have exciting potential, findings suggest that further research is necessary to establish consistent benefits for lung cancer specifically.
Read More
9
We investigated the impact of cruciferous vegetables, especially broccoli, on lung cancer risk, focusing on genetic factors.
In a study involving over 4,000 participants, we discovered that those with specific genetic profiles (GSTM1 and GSTT1 null) showed a significant reduction in lung cancer risk with regular consumption of these vegetables.
Notably, those avoiding these genes exhibited even greater benefits. However, individuals with both genes present didn’t experience any protective effects. Overall, our findings point to a strong link between eating cruciferous veggies and lower lung cancer risk in certain populations.
In a study involving over 4,000 participants, we discovered that those with specific genetic profiles (GSTM1 and GSTT1 null) showed a significant reduction in lung cancer risk with regular consumption of these vegetables.
Notably, those avoiding these genes exhibited even greater benefits. However, individuals with both genes present didn’t experience any protective effects. Overall, our findings point to a strong link between eating cruciferous veggies and lower lung cancer risk in certain populations.
Read More
8
We explored the potential of sulforaphane (SFN), a compound found in broccoli, to combat lung cancer. Our study used both laboratory tests and mouse models to investigate how SFN affects lung cancer cells.
Results indicated that SFN successfully inhibited an enzyme called HDAC, leading to increased levels of certain proteins that promote cell death. Additionally, SFN slowed down the growth of lung tumors in mice.
While the findings are promising for SFN as a lung cancer treatment, further research is needed to fully understand its efficacy in humans.
Results indicated that SFN successfully inhibited an enzyme called HDAC, leading to increased levels of certain proteins that promote cell death. Additionally, SFN slowed down the growth of lung tumors in mice.
While the findings are promising for SFN as a lung cancer treatment, further research is needed to fully understand its efficacy in humans.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 24 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Inflammation reduction
3 people found this helpful
Broccoli sprouts are effective in cancer prevention and reducing digestive inflammation. Sulforaphane induces cancer cell apoptosis and diminishes DNA damage. These vegetable capsules serve as a convenient and beneficial alternative for me, as they help maintain intestinal health and prevent cancer.
Read More
9
Effective detoxification
Sulforaphane not only prevents harmful substances from becoming carcinogens but also helps convert them into water-soluble substances that can be eliminated from the body.
Read More
7.5
Slowed progression
10 people found this helpful
Using Jarrow Formulas, Brocco Max has seemingly arrested the growth rate of my Prostate Cancer. While certainty is elusive, I’ve noticed significant improvement since starting this supplement.
Read More
9
Prevent recurrence
6 people found this helpful
As a breast cancer survivor, I began taking this product to help prevent recurrence. I found that it also helps avoid hangovers even after moderate drinking. It seems that sulforaphane is effective, and the supplement's quality is quite good and easy to swallow.
Read More
9
Research-backed
6 people found this helpful
Broccoli, hailed as the queen of women's supplements, contains sulforaphane, which exhibits proven anti-cancer and anti-toxic properties. Research regarding sulforaphane is extensive, and its benefits for estrogen balance against mastopathy are well-documented. However, to gain sulforaphane from raw broccoli, preparation is crucial, and Jarrow's supplement includes necessary myrosinase enzyme.
Read More
Frequently Asked Questions
7.5
Wellbeing improvement
1 people found this helpful
On my first bottle of Broccomax, I’ve begun experiencing improved energy and liver health. The benefits aren’t immediately evident but accumulate over time, enhancing my overall wellbeing. I believe the anti-cancer properties and liver detox support from sulforaphane are worth adding to my supplement regimen. After finishing my first bottle, I plan to reduce the dosage to manage costs while ensuring a regular supply of sulforaphane.
7.5
Slowed progression
10 people found this helpful
Using Jarrow Formulas, Brocco Max has seemingly arrested the growth rate of my Prostate Cancer. While certainty is elusive, I’ve noticed significant improvement since starting this supplement.
9
Inflammation reduction
3 people found this helpful
Broccoli sprouts are effective in cancer prevention and reducing digestive inflammation. Sulforaphane induces cancer cell apoptosis and diminishes DNA damage. These vegetable capsules serve as a convenient and beneficial alternative for me, as they help maintain intestinal health and prevent cancer.
7.5
Improved liver function
5 people found this helpful
I trust Jarrow's Brocco Max, having used it for a few years since my cancer diagnosis. Sulforaphane has been effective for me in suppressing lung cancer and enhancing liver function. While I don’t attribute my recovery solely to this, I've successfully completed my treatment, and my liver values have remained stable for years. Though broccoli and sulforaphane are superfoods, supplements help with intake, which I plan to continue.
6
Cancer properties noted
7 people found this helpful
I take this supplement for a persistent H. Pylori infection, complemented by other remedies. It has transformed my health from debilitating symptoms to a near-normal state. Additionally, it offers anti-cancer benefits.
7.5
Stronger lung defense
4 people found this helpful
Jarrow Formulas BroccoMax is an excellent product for my COPD. After extensive research, I find this product meets my needs for enhancing lung defence against infections. However, it’s quite difficult to find!
6
Reduces cancer risk
8 people found this helpful
My favourite broccoli is a source of sulforaphane, renowned for its antioxidant, antimicrobial, and anti-inflammatory properties. Consuming it regularly can reduce body fat and lower cancer risk. Although not everyone enjoys its taste and cooking diminishes sulforaphane, I supplement with broccoli extract to aid absorption.
7.5
Belief in benefits
3 people found this helpful
As a cancer survivor, I try to consume as much broccoli as possible, whether in sprouts, raw, or cooked, and now this supplement. I genuinely believe they help me, and my nutritionist agrees.
9.5
We examined the effects of sulforaphane, a compound in broccoli, on lung cancer treatment. Our research focused on its ability to stop cell growth and induce cell death in lung adenocarcinoma cells, revealing that it can significantly halt tumor growth in animal models.
The study found that sulforaphane led to a marked reduction in tumor weight compared to untreated mice. While these results are promising for broccoli-derived treatments, further research is essential to understand its full potential in human applications, as we still need to see how these findings translate to actual lung cancer patients.
The study found that sulforaphane led to a marked reduction in tumor weight compared to untreated mice. While these results are promising for broccoli-derived treatments, further research is essential to understand its full potential in human applications, as we still need to see how these findings translate to actual lung cancer patients.
9
We investigated the impact of cruciferous vegetables, especially broccoli, on lung cancer risk, focusing on genetic factors.
In a study involving over 4,000 participants, we discovered that those with specific genetic profiles (GSTM1 and GSTT1 null) showed a significant reduction in lung cancer risk with regular consumption of these vegetables.
Notably, those avoiding these genes exhibited even greater benefits. However, individuals with both genes present didn’t experience any protective effects. Overall, our findings point to a strong link between eating cruciferous veggies and lower lung cancer risk in certain populations.
In a study involving over 4,000 participants, we discovered that those with specific genetic profiles (GSTM1 and GSTT1 null) showed a significant reduction in lung cancer risk with regular consumption of these vegetables.
Notably, those avoiding these genes exhibited even greater benefits. However, individuals with both genes present didn’t experience any protective effects. Overall, our findings point to a strong link between eating cruciferous veggies and lower lung cancer risk in certain populations.
7
We evaluated whether broccoli-derived vesicles (BDVs) could impact cancer cell activity, specifically in lung cancer. Using an in vitro setup, we isolated BDVs, tested their effects on different cancer cell lines, and measured various indicators of cell metabolism and antioxidant activity.
While BDVs showed some ability to reduce harmful reactive oxygen species in certain cell types, we found that their overall anti-cancer effects were not consistently significant, particularly in lung adenocarcinoma cells. More research is needed to fully understand these vesicles' potential for treatment.
While BDVs showed some ability to reduce harmful reactive oxygen species in certain cell types, we found that their overall anti-cancer effects were not consistently significant, particularly in lung adenocarcinoma cells. More research is needed to fully understand these vesicles' potential for treatment.
References
- Hossain MN, De Leo V, Tamborra R, Laselva O, Ingrosso C, et al. Characterization of anti-proliferative and anti-oxidant effects of nano-sized vesicles from Brassica oleracea L. (Broccoli). Sci Rep. 2022;12:14362. 10.1038/s41598-022-17899-1
- García-Lavandeira JA, Ruano-Ravina A, Torres-Durán M, Parente-Lamelas I, Provencio M, et al. Fruits and Vegetables and Lung Cancer Risk in Never Smokers. A Multicentric and Pooled Case-Control Study. Nutr Cancer. 2022;74:613. 10.1080/01635581.2021.1918732
- Manikandan T, Padmalaya G, Mahalakshmi S, Nivethitha AS, Pavithran V, et al. Facile hydrothermal bio-synthesis of cellulose acetate templated CuS nanorods like fibres: antibacterial, cytotoxicity effects and DNA cleavage properties against A549 lung cancer cells. IET Nanobiotechnol. 2020;14:47. 10.1049/iet-nbt.2019.0193
- Kwak BS, Hwang D, Lee SJ, Choi HJ, Park HY, et al. Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation. J Med Food. 2019;22:451. 10.1089/jmf.2018.4286
- Dinkova-Kostova AT, Fahey JW, Kostov RV, Kensler TW. KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane. Trends Food Sci Technol. 2017;69:257. 10.1016/j.tifs.2017.02.002
- Żuryń A, Litwiniec A, Safiejko-Mroczka B, Klimaszewska-Wiśniewska A, Gagat M, et al. The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line. Int J Oncol. 2016;48:2521. 10.3892/ijo.2016.3444
- Jiang LL, Zhou SJ, Zhang XM, Chen HQ, Liu W. Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity. Biomed Pharmacother. 2016;78:74. 10.1016/j.biopha.2015.11.007
- Tarrazo-Antelo AM, Ruano-Ravina A, Abal Arca J, Barros-Dios JM. Fruit and vegetable consumption and lung cancer risk: a case-control study in Galicia, Spain. Nutr Cancer. 2014;66:1030. 10.1080/01635581.2014.936951
- Kalpana Deepa Priya D, Gayathri R, Gunassekaran GR, Murugan S, Sakthisekaran D. Apoptotic role of natural isothiocyanate from broccoli (Brassica oleracea italica) in experimental chemical lung carcinogenesis. Pharm Biol. 2013;51:621. 10.3109/13880209.2012.761242
- Priya DK, Gayathri R, Gunassekaran G, Murugan S, Sakthisekaran D. Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre- and post-initiation phases of experimental lung carcinogenesis. Asian Pac J Cancer Prev. 2011;12:103.
- Carpenter CL, Yu MC, London SJ. Dietary isothiocyanates, glutathione S-transferase M1 (GSTM1), and lung cancer risk in African Americans and Caucasians from Los Angeles County, California. Nutr Cancer. 2009;61:492. 10.1080/01635580902752270
- Liang H, Lai B, Yuan Q. Sulforaphane induces cell-cycle arrest and apoptosis in cultured human lung adenocarcinoma LTEP-A2 cells and retards growth of LTEP-A2 xenografts in vivo. J Nat Prod. 2008;71:1911. 10.1021/np800233q
- Brennan P, Hsu CC, Moullan N, Szeszenia-Dabrowska N, Lissowska J, et al. Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach. Lancet. 2005;366:1558.
- Caicoya M. [Lung cancer and vegetable consumption in Asturias, Spain. A case control study]. Med Clin (Barc). 2002;119:206.
