Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
Supplement Facts
Serving Size: 2 Softgels
Serving Per Container:  120
Amount Per Serving
%DV
Calories
20
 
Total Fat
2 g
3%‡
Cholesterol
11 mg
4%‡
Protein
<1 g
Fish Oil Concentrate^
2,000 mg
Omega-3 Fatty Acids^
1,200 mg
EPA (Eicosapentaenoic Acid)^
800 mg
DHA (Docosahexaenoic Acid)^
400 mg

Top Medical Research Studies

8
Eicosapentaenoic acid shows potential
We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.

These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
Read More
9
Effective treatment for fatigue syndrome
We conducted a thorough investigation into the effects of essential fatty acids, including eicosapentaenoic acid (EPA), on individuals suffering from postviral fatigue syndrome. In a well-structured trial, 63 adults with this condition participated in a double-blind, placebo-controlled study. They had been living with severe fatigue and other troubling symptoms for one to three years following a viral infection.

Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.

Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.
Read More
8
Eicosapentaenoic acid's potential in CFS
We explored the connection between eicosapentaenoic acid (EPA) and chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis. The research indicates that individuals suffering from CFS may experience complications linked to persistent viral infections, which could hinder their body's ability to produce necessary fatty acids.

Specifically, the issue revolves around the enzyme delta-6 desaturase, which plays a critical role in the conversion of essential fatty acids like alpha-linolenic acid and linoleic acid into longer chain polyunsaturated fatty acids. These fatty acids are vital for maintaining healthy cell membranes and proper cell signaling. If their production is inhibited, it could explain many symptoms associated with CFS.

One intriguing aspect we observed is the potential therapeutic role that EPA could play. By providing EPA directly, we may bypass some of the metabolic restrictions caused by viral infections. This not only aids in generating essential fatty acids needed for bodily functions but also shows promise as a treatment option that could alleviate certain symptoms of CFS.

While the exact impact of EPA treatment on CFS warrants further investigation, the findings suggest that it might offer some benefits worth considering for those affected by this challenging condition.
Read More

Most Useful Reviews

9
Lessened symptoms
3 people found this helpful
This has significantly helped with my chronic mental illness, reducing symptoms and restoring peace. I took four pills daily to reach around 2000mg of EPA. Results appeared within two weeks. I initially started with one pill daily for menstrual cramps and mental fog, and I'm hopeful for further improvements.
Read More
9
Less fatigue
1 people found this helpful
On my doctor’s advice, I began taking these to enhance my well-being and alleviate lethargy. I'm pleased to say it has helped!
Read More
7.5
Enhanced cognition
1 people found this helpful
Since taking the EPA-DHA Balance® fish oil capsules, I’ve noticed less fatigue and improved concentration. They’re easy to swallow without a fishy aftertaste, and this product lasts ages. I highly recommend it for overall cardiovascular health and cognitive function.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
  • All Researches
9
Effective treatment for fatigue syndrome
We conducted a thorough investigation into the effects of essential fatty acids, including eicosapentaenoic acid (EPA), on individuals suffering from postviral fatigue syndrome. In a well-structured trial, 63 adults with this condition participated in a double-blind, placebo-controlled study. They had been living with severe fatigue and other troubling symptoms for one to three years following a viral infection.

Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.

Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.
Read More
8
EPA supplementation shows promise
We investigated the effects of a daily eicosapentaenoic acid (EPA)-rich supplement on a woman suffering from chronic fatigue syndrome for six years. After 16 weeks of treatment, she experienced significant symptom relief starting within the first 6-8 weeks.

Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
Read More
8
Eicosapentaenoic acid shows potential
We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.

These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
Read More
8
Eicosapentaenoic acid's potential in CFS
We explored the connection between eicosapentaenoic acid (EPA) and chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis. The research indicates that individuals suffering from CFS may experience complications linked to persistent viral infections, which could hinder their body's ability to produce necessary fatty acids.

Specifically, the issue revolves around the enzyme delta-6 desaturase, which plays a critical role in the conversion of essential fatty acids like alpha-linolenic acid and linoleic acid into longer chain polyunsaturated fatty acids. These fatty acids are vital for maintaining healthy cell membranes and proper cell signaling. If their production is inhibited, it could explain many symptoms associated with CFS.

One intriguing aspect we observed is the potential therapeutic role that EPA could play. By providing EPA directly, we may bypass some of the metabolic restrictions caused by viral infections. This not only aids in generating essential fatty acids needed for bodily functions but also shows promise as a treatment option that could alleviate certain symptoms of CFS.

While the exact impact of EPA treatment on CFS warrants further investigation, the findings suggest that it might offer some benefits worth considering for those affected by this challenging condition.
Read More
4
Omega-3s may help CFS patients
We explored the connection between omega-3 fatty acids and chronic fatigue syndrome (CFS) by examining serum levels in 22 CFS patients and 12 healthy controls. Our findings revealed that CFS patients had lower omega-3 levels compared to controls, along with higher omega-6 levels.

Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Lessened symptoms
3 people found this helpful
This has significantly helped with my chronic mental illness, reducing symptoms and restoring peace. I took four pills daily to reach around 2000mg of EPA. Results appeared within two weeks. I initially started with one pill daily for menstrual cramps and mental fog, and I'm hopeful for further improvements.
Read More
9
Less fatigue
1 people found this helpful
On my doctor’s advice, I began taking these to enhance my well-being and alleviate lethargy. I'm pleased to say it has helped!
Read More
7.5
Enhanced cognition
1 people found this helpful
Since taking the EPA-DHA Balance® fish oil capsules, I’ve noticed less fatigue and improved concentration. They’re easy to swallow without a fishy aftertaste, and this product lasts ages. I highly recommend it for overall cardiovascular health and cognitive function.
Read More
9
Eliminated fatigue
I've been taking this for several months and have noticed a significant improvement in my condition; the chronic fatigue syndrome symptoms have disappeared.
Read More
7.5
Improved mental health
8 people found this helpful
This product has been beneficial for me; I noticed an antidepressant effect and reduced fatigue since starting. After taking five capsules daily, I've managed to lower my other supplements for depression, indicating I may have had an omega-3 deficiency for years. Now, two capsules suffice to maintain the effect.
Read More

Frequently Asked Questions

9
Lessened symptoms
3 people found this helpful
This has significantly helped with my chronic mental illness, reducing symptoms and restoring peace. I took four pills daily to reach around 2000mg of EPA. Results appeared within two weeks. I initially started with one pill daily for menstrual cramps and mental fog, and I'm hopeful for further improvements.
9
Eliminated fatigue
I've been taking this for several months and have noticed a significant improvement in my condition; the chronic fatigue syndrome symptoms have disappeared.
7.5
Improved mental health
8 people found this helpful
This product has been beneficial for me; I noticed an antidepressant effect and reduced fatigue since starting. After taking five capsules daily, I've managed to lower my other supplements for depression, indicating I may have had an omega-3 deficiency for years. Now, two capsules suffice to maintain the effect.
7.5
Reduced tiredness
I can't tell yet how effective this is, but I've noticed a significant reduction in fatigue. It would be nice to have more energy.
9
Less fatigue
1 people found this helpful
On my doctor’s advice, I began taking these to enhance my well-being and alleviate lethargy. I'm pleased to say it has helped!
7.5
Enhanced cognition
1 people found this helpful
Since taking the EPA-DHA Balance® fish oil capsules, I’ve noticed less fatigue and improved concentration. They’re easy to swallow without a fishy aftertaste, and this product lasts ages. I highly recommend it for overall cardiovascular health and cognitive function.
7.5
Improved well-being
1 people found this helpful
I've been advised by a trichologist to take omega regularly, leading to marked improvements in hair condition and reduced chronic fatigue syndrome symptoms. My skin hydration improved, and I no longer experience eye fatigue, making prolonged screen time much easier.
4
Omega-3s may help CFS patients
We explored the connection between omega-3 fatty acids and chronic fatigue syndrome (CFS) by examining serum levels in 22 CFS patients and 12 healthy controls. Our findings revealed that CFS patients had lower omega-3 levels compared to controls, along with higher omega-6 levels.

Interestingly, we observed that these imbalances correlated with the severity of fatigue and other symptoms. Additionally, lower omega-3 availability linked to poorer immune function was noted. These results suggest that omega-3 supplementation could be beneficial for those suffering from CFS.
8
EPA supplementation shows promise
We investigated the effects of a daily eicosapentaenoic acid (EPA)-rich supplement on a woman suffering from chronic fatigue syndrome for six years. After 16 weeks of treatment, she experienced significant symptom relief starting within the first 6-8 weeks.

Additionally, brain scans revealed a notable reduction in the size of her lateral ventricles, which is promising. This early-stage observation suggests that EPA supplementation might offer benefits for individuals dealing with chronic fatigue syndrome.
8
Eicosapentaenoic acid shows potential
We assessed how eicosapentaenoic acid, an essential fatty acid, impacts chronic fatigue syndrome (CFS). A group of CFS patients took a specific supplement rich in this fatty acid. Remarkably, every participant reported symptom improvement within eight to twelve weeks.

These findings align with other research that shows the positive effects of eicosapentaenoic acid, hinting that it could be a promising treatment option for some individuals living with CFS.
8
Eicosapentaenoic acid's potential in CFS
We explored the connection between eicosapentaenoic acid (EPA) and chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis. The research indicates that individuals suffering from CFS may experience complications linked to persistent viral infections, which could hinder their body's ability to produce necessary fatty acids.

Specifically, the issue revolves around the enzyme delta-6 desaturase, which plays a critical role in the conversion of essential fatty acids like alpha-linolenic acid and linoleic acid into longer chain polyunsaturated fatty acids. These fatty acids are vital for maintaining healthy cell membranes and proper cell signaling. If their production is inhibited, it could explain many symptoms associated with CFS.

One intriguing aspect we observed is the potential therapeutic role that EPA could play. By providing EPA directly, we may bypass some of the metabolic restrictions caused by viral infections. This not only aids in generating essential fatty acids needed for bodily functions but also shows promise as a treatment option that could alleviate certain symptoms of CFS.

While the exact impact of EPA treatment on CFS warrants further investigation, the findings suggest that it might offer some benefits worth considering for those affected by this challenging condition.

References

  1. Maes M, Mihaylova I, Leunis JC. In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation. Neuro Endocrinol Lett. 2005;26:745.
  2. Puri BK, Holmes J, Hamilton G. Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes. Int J Clin Pract. 2004;58:297.
  3. Puri BK. The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids. 2004;70:399.
  4. Puri BK. Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). J Clin Pathol. 2007;60:122.
  5. Behan PO, Behan WM, Horrobin D. Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol Scand. 1990;82:209.
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