We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.
Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.
Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
8
Omega-3s reduce headache frequency
Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial.
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.
Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.
Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol.
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.
While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.
This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Read More
Most Useful Reviews
10
Migraine relief
1 people found this helpful
Amazing!!! I have battled migraine headaches all my life, experiencing 3-5 weekly in severe cases. Since starting Max DHA two months ago, I haven’t had one! I’m a lifetime customer now!
Read More
10
Migraine relief
The migraine is gone; headaches have ceased entirely. Smoker's must-try.
Read More
9
Headache relief
The capsules are transparent and have no taste unless chewed. They are quite large at 2.5 cm but swallowing them is easy. I took one Jarrow Formulas EPA-DHA balance capsule every morning with breakfast. Occasionally, I would forget them during meals and take them afterward. The jar lasts for four months. My results include more hydrated hair and skin, no more cracking heels, reduced illness, and headaches that have ceased. I've also lost a bit of weight. I highly recommend it. 👍🏼
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.
Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.
Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
Read More
9
Omega-3 diet improves headaches
Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial.
We examined how adjusting omega-3 and omega-6 fatty acids influences chronic headaches and overall well-being. In a randomized trial with 67 participants suffering from severe headaches, those who increased omega-3 intake while decreasing omega-6 saw significant improvements in their headaches and reductions in psychological distress.
Over 12 weeks, participants in this dietary intervention reported better mental and physical health, which also helped decrease the number of headache days. Overall, this approach not only targets headache relief but also enhances quality of life.
Read More
9
Omega-3s reduce chronic headaches
Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
Read More
8
Omega-3s reduce headache frequency
Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial.
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.
Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.
Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
Read More
8
Omega-3 fish oil reduces headaches
Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol.
We explored the effects of a 12-week omega-3 fish oil supplement, Omega3Q10, among older adults dealing with high blood pressure and cholesterol. The study included 97 participants, who were split between the omega-3 group and a control group receiving soybean oil.
While both groups saw improvements in cholesterol levels, those taking Omega3Q10 experienced greater benefits in managing blood pressure and reported fewer headaches. An impressive 95.5% of omega-3 participants were headache-free after the trial, compared to just 71.4% in the soybean oil group.
This suggests that omega-3 fish oil may be a valuable addition for older adults looking to improve both heart health and reduce headache symptoms.
Amazing!!! I have battled migraine headaches all my life, experiencing 3-5 weekly in severe cases. Since starting Max DHA two months ago, I haven’t had one! I’m a lifetime customer now!
Read More
10
Migraine relief
The migraine is gone; headaches have ceased entirely. Smoker's must-try.
Read More
9
Headache relief
The capsules are transparent and have no taste unless chewed. They are quite large at 2.5 cm but swallowing them is easy. I took one Jarrow Formulas EPA-DHA balance capsule every morning with breakfast. Occasionally, I would forget them during meals and take them afterward. The jar lasts for four months. My results include more hydrated hair and skin, no more cracking heels, reduced illness, and headaches that have ceased. I've also lost a bit of weight. I highly recommend it. 👍🏼
Read More
9
Headache cessation
I really liked the omega; the headaches that troubled me nearly every day have now stopped. My skin has become clear and moisturised, and my hair is shiny. I definitely recommend this product.
Read More
6
Suppressed headaches
2 people found this helpful
I don't take it every day, but sometimes I have a headache before and after my period. When I take it, I feel that it is suppressed. I want to take Omega 3 daily if the quality is good. It is difficult to determine quality, so I often change manufacturers. Ultimately, I believe that if you select a highly regarded product, the freshness should be good. Some might struggle without it.
A headache is a common condition characterized by pain or discomfort in the head, scalp, or neck. It can vary in intensity, frequency, and duration, and is often classified into two primary categories: primary and secondary headaches. Primary headaches, such as tension-type headaches, migraines, and cluster headaches, are not caused by other medical conditions. Instead, they are conditions in themselves, often resulting from factors like stress, hormonal changes, or environmental triggers. Secondary headaches, on the other hand, are symptoms of an underlying issue, such as an infection, injury, or other medical conditions.
The experience of a headache can differ widely among individuals. Depending on the type, headaches can be throbbing or constant and may be accompanied by other symptoms like nausea, sensitivity to light, or aura effects before the headache strikes. Effective management strategies vary by headache type and may include over-the-counter pain relievers, lifestyle changes, and in some cases, prescription medications. Understanding the specific triggers and patterns related to your headaches can be crucial for prevention and treatment, so maintaining a headache diary may be beneficial for those experiencing frequent or severe episodes.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Research suggests that Omega-3 fish oil may have potential benefits for reducing certain types of headaches, particularly migraines. Omega-3 fatty acids, found in fish oil, are known for their anti-inflammatory properties, which can play a role in alleviating headache symptoms. A few studies indicate that individuals who consume higher amounts of Omega-3s tend to experience fewer and less severe headaches compared to those with lower intake. However, it's essential to note that while Omega-3 fish oil can be beneficial for overall health, its effectiveness as a treatment for headaches can vary significantly from person to person.
Before incorporating Omega-3 fish oil into your regimen specifically for headaches, it’s advisable to consult with a healthcare professional. They can provide personalized recommendations based on your medical history and the characteristics of your headaches. Additionally, it's crucial to consider that while Omega-3s can be a helpful supplement, they should not replace prescribed medications or treatments for headache management. As with any supplement, moderation and proper dosage are key—overconsumption can lead to side effects. Ultimately, a comprehensive approach that includes lifestyle changes, stress management, and dietary adjustments may yield the best results.
Based on user reviews, many individuals experience positive results regarding headaches from taking this supplement relatively quickly, often within a week. For instance, one user noted that after just a week of taking the supplement, their headaches ceased, and they felt less tired overall Read Review. Another user reported that their headaches had entirely stopped after consistent use Read Review. This suggests that if you are considering this supplement, you might begin to notice a reduction in headache frequency and severity shortly after beginning your regimen.
Additionally, several users highlight long-term benefits, stating that with continued use over months or even years, their headaches have significantly lessened or disappeared entirely. For example, one user mentioned that after three years of taking the supplement, their headaches no longer tormented them Read Review. Thus, while some may experience quick relief within a week, others see more gradual improvements with consistent use, indicating the supplement could be beneficial for various users.
Research supports the use of omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as beneficial supplements for alleviating headache symptoms, especially in those with chronic migraines. Multiple studies indicate significant improvements in headache frequency and severity among participants consuming higher doses of omega-3s. For instance, a trial demonstrated that EPA supplementation reduced the number of migraine days per month by an average of 4.4 days compared to a placebo group [3]. Additionally, dietary changes that included increased omega-3 intake were linked to notable decreases in headache intensity and medication use [6].
Moreover, findings suggest that elevating omega-3 levels while reducing omega-6 fatty acids can enhance overall well-being and lead to improved outcomes for those suffering from chronic headaches [15]. In fact, one study reported that 66.7% of participants using omega-3 alongside standard treatment experienced more than an 80% reduction in headache days [14]. While the evidence is compelling, the necessity for further research to establish definitive guidelines on dosages and long-term efficacy remains. Thus, even though omega-3 supplements show promise in headache management, they should ideally be considered as part of a comprehensive treatment plan.
Based on user reviews, many individuals report significant improvements in headache symptoms after using this supplement. For instance, one user noted that their migraines disappeared entirely, while another shared that their daily headaches ceased after consistent use Read ReviewRead Review. Furthermore, long-term users emphasize that with continued use over months or even years, they have experienced a marked reduction in headache frequency and severity, with one user stating that they no longer suffer from headaches as they used to Read Review.
Additionally, some users report a general improvement in their overall wellness, including reduced fatigue and enhanced skin and hair health alongside headache relief Read ReviewRead Review. However, individual experiences may vary widely, and while some find relief almost immediately, others may need a longer commitment to see similar benefits. The anecdotal nature of these testimonials suggests that the supplement might help a range of users experience enhanced well-being along with relief from headache symptoms.
Users report varying experiences when combining this supplement with other products for headache management. Some individuals, like one who has taken the supplement for three years, mention consistently taking it alongside Vitamin D, which they believe contributes to their significant reduction in headache frequency Read Review. Another user noted that they often take the supplement during specific times, such as before and after their menstrual cycle, which helps to suppress their headaches during this period Read Review.
Additionally, several reviews indicate that users have experienced headaches significantly alleviated or completely resolved when taking this supplement regularly, with some stating that they had positive results when using it in conjunction with other wellness products Read Review. However, the efficacy of combining various supplements may depend on individual needs and health conditions, highlighting the importance of finding a suitable regimen that works for each user.
According to research, the optimal dosing for Omega-3 Fish Oil, particularly eicosapentaenoic acid (EPA), appears to be around 2000 mg daily for managing headaches, especially for migraine sufferers. A study involving chronic migraine patients reported significant reductions in the frequency and severity of migraine attacks with this dosage over an eight-week period [2]. Similarly, an additional study found that participants taking 2 grams of fish oil containing 1.8 grams of pure EPA daily experienced a notable decrease in migraine days compared to those receiving a placebo [3].
In general, higher intakes of Omega-3 fatty acids, particularly EPA and docosahexaenoic acid (DHA), are associated with improvements in headache symptoms. The effectiveness of dietary changes that increase omega-3s while decreasing omega-6s has also been suggested, as seen in various studies that indicate a beneficial impact on headache frequency and intensity [19]. Overall, while individual responses to Omega-3 Fish Oil supplementation can vary, these findings support a higher intake of omega-3s, particularly EPA, as a promising strategy for headache management.
9
No more headaches
After a week of use, I became less tired and have no headaches. The capsules are good, and I continue to take them.
9
Headache cessation
I really liked the omega; the headaches that troubled me nearly every day have now stopped. My skin has become clear and moisturised, and my hair is shiny. I definitely recommend this product.
7.5
Less frequent headaches
I have been taking this for three years continuously and have noticed many positive changes. My health has improved and the headaches no longer torment me as they used to. I take it with Vitamin D together. I recommend it.
10
Migraine relief
The migraine is gone; headaches have ceased entirely. Smoker's must-try.
9
Headache relief
The capsules are transparent and have no taste unless chewed. They are quite large at 2.5 cm but swallowing them is easy. I took one Jarrow Formulas EPA-DHA balance capsule every morning with breakfast. Occasionally, I would forget them during meals and take them afterward. The jar lasts for four months. My results include more hydrated hair and skin, no more cracking heels, reduced illness, and headaches that have ceased. I've also lost a bit of weight. I highly recommend it. 👍🏼
7.5
Fatigue and headache
Excellent Omega 3! My mother drinks it in courses and feels very happy as it helps her combat fatigue and headaches.
6
Suppressed headaches
2 people found this helpful
I don't take it every day, but sometimes I have a headache before and after my period. When I take it, I feel that it is suppressed. I want to take Omega 3 daily if the quality is good. It is difficult to determine quality, so I often change manufacturers. Ultimately, I believe that if you select a highly regarded product, the freshness should be good. Some might struggle without it.
9.5
EPA shows promise for migraine relief
A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine.
We examined the effects of eicosapentaenoic acid (EPA) on episodic migraine patients through a 12-week randomized double-blind trial. Seventy participants were divided into two groups, one receiving EPA and the other a placebo.
Those taking the EPA experienced significant decreases in migraine frequency, medication use, headache severity, and improvements in overall quality of life.
Notably, women benefitted particularly from this treatment. Overall, high-dose EPA showed promise as an effective preventive option for episodic migraines, with no major side effects observed.
8
Omega-3s reduce headache frequency
Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial.
We conducted a randomized controlled trial to explore whether increasing omega-3 fatty acids would help reduce headaches in adults suffering from migraines.
Over 16 weeks, 182 participants followed three different dietary plans focusing on varying levels of omega-3s while monitoring headache impact.
Though the diets with higher omega-3 levels did show a reduction in headache frequency and severity, they didn't significantly improve overall quality of life. This suggests that omega-3s may help with headaches but not enhance daily functioning.
8
Omega-3 diet improves headache relief
Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress.
We explored how modifying our diet to increase omega-3 fatty acids while decreasing omega-6 can impact headache pain. In a study involving 55 chronic headache patients, we found that this dietary approach significantly boosted beneficial omega-3-derived compounds in the bloodstream and reduced harmful omega-6 derivatives.
These changes were closely linked to notable improvements in headache intensity and psychological well-being. Ultimately, our findings suggest that adjusting our intake of these fatty acids may offer a valuable method for alleviating chronic headaches and improving overall mental health.
8
Omega-3 reduces migraine frequency
A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline.
We explored the effectiveness of omega-3 fatty acids in preventing chronic migraine attacks through a well-structured double-blind study. Sixty patients diagnosed with chronic migraines were split into two groups: one received omega-3 alongside amitriptyline, while the other got a placebo.
After 60 days, we observed that 66.7% of the omega-3 group reported more than an 80% reduction in headache days, compared to only 33.3% in the control group. This shows promise for omega-3 as a migraine preventive, though further study is needed to solidify these findings.
7
EPA supplementation may reduce migraines
Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial.
We conducted a randomized, placebo-controlled trial to explore the effects of daily 2000 mg of eicosapentaenoic acid (EPA) on chronic migraines. Over 8 weeks, participants recorded their headache symptoms, with some taking EPA and others receiving a placebo.
Our findings suggest that EPA may significantly reduce the frequency of migraine attacks and improve overall quality of life for chronic migraine sufferers. However, we believe that more research is needed for a clearer understanding of its benefits and dosage.
9
Omega-3s reduce chronic headaches
Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial.
We conducted a study to understand how changes in the intake of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), can influence chronic headaches. By focusing on one group consuming a high level of omega-3 and low omega-6, while another group maintained a low omega-6 diet, we aimed to identify any significant improvements in headache symptoms over a 12-week period.
Our findings revealed notable advantages in the group that increased their omega-3 intake. This group reported greater reductions in headache days and hours, alongside improved overall quality of life. Specifically, the high omega-3 group showed a remarkable drop in their headache impact scores, suggesting that eicosapentaenoic acid may play a beneficial role in managing headache pain.
These results shed light on the potential of dietary adjustments in fatty acid intake as a proactive approach to treating chronic headaches. Eicosapentaenoic acid, thanks to its effects on pain relief pathways, seems to contribute positively to this outcome, affording patients a new avenue to explore in their headache management strategies.
References
Yeh EL, Yang CP, Lin SW, Wang HF. Feasibility of Fish Oil Supplementation on Headache Symptoms and Blood Lipids in Migraine Patients. Brain Behav. 2024;14:e70149. 10.1002/brb3.70149
Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. 10.1111/head.14808
Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. 10.1016/j.bbi.2024.03.019
Sanders AE, Weatherspoon ED, Ehrmann BM, Soma PS, Shaikh SR, et al. Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions. J Pain. 2023;24:478. 10.1016/j.jpain.2022.10.008
Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. 10.1016/j.cct.2022.106851
Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. 10.1136/bmj.n1448
Honarvar NM, Soveid N, Abdolahi M, Djalali M, Hatami M, et al. Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano- Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial. Endocr Metab Immune Disord Drug Targets. 2021;21:365. 10.2174/1871530320666200729144430
Abdolahi M, Jafarieh A, Sarraf P, Sedighiyan M, Yousefi A, et al. The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Endocr Metab Immune Disord Drug Targets. 2019;19:874. 10.2174/1871530319666190212170140
Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. 10.1016/j.plefa.2018.06.008
Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. 10.1016/j.plefa.2017.11.002
Shen T, Xing G, Zhu J, Zhang S, Cai Y, et al. Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol. Lipids Health Dis. 2017;16:253. 10.1186/s12944-017-0617-0
Soveyd N, Abdolahi M, Djalali M, Hatami M, Tafakhori A, et al. The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients. CNS Neurol Disord Drug Targets. 2018;16:1120. 10.2174/1871527317666171213154749
Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69:371. 10.1007/s00251-017-0992-8
Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. 10.1080/1028415X.2016.1266133
Ramsden CE, Zamora D, Makriyannis A, Wood JT, Mann JD, et al. Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain. 2015;16:707. 10.1016/j.jpain.2015.04.007
Ramsden CE, Faurot KR, Zamora D, Palsson OS, MacIntosh BA, et al. Targeted alterations in dietary n-3 and n-6 fatty acids improve life functioning and reduce psychological distress among patients with chronic headache: a secondary analysis of a randomized trial. Pain. 2015;156:587. 10.1097/01.j.pain.0000460348.84965.47
Sadeghi O, Maghsoudi Z, Khorvash F, Ghiasvand R, Askari G. The relationship between different fatty acids intake and frequency of migraine attacks. Iran J Nurs Midwifery Res. 2015;20:334.
Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, et al. Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools. Prostaglandins Leukot Essent Fatty Acids. 2014;90:151. 10.1016/j.plefa.2014.02.003
Ramsden CE, Faurot KR, Zamora D, Suchindran CM, MacIntosh BA, et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial. Pain. 2013;154:2441. 10.1016/j.pain.2013.07.028
Domenichiello AF, Jensen JR, Zamora D, Horowitz M, Yuan ZX, et al. Identifying oxidized lipid mediators as prognostic biomarkers of chronic posttraumatic headache. Pain. 2020;161:2775. 10.1097/j.pain.0000000000001983